Identification and characterization of MARVELD1, a novel nuclear protein that is down-regulated in multiple cancers and silenced by DNA methylation

Cancer Letters

Volumn 282, Issue 1, 2009, Pages 77-86

  Wang, Shan ^a   Li, Yu ^a   Han, Fang ^a   Hu, Jianran ^a   Yue, Lei ^a   Yu, Youtao ^b   Zhang, Yubao ^b   He, Jie ^a   Zheng, Hongxia ^a   Shi, Shuliang ^a   Fu, Xiaowei ^b   Wu, Hongjin ^a  

^a HARBIN INSTITUTE OF TECHNOLOGY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; Expression down regulation; MARVELD1; Tumor

Indexed keywords

NUCLEAR PROTEIN; PROTEIN MARVELD1; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL MEMBRANE; CELL NUCLEUS; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE LOCATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MULTIPLE CANCER; NUCLEOTIDE SEQUENCE; PRIMARY TUMOR; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

CELL MEMBRANE; CELL NUCLEUS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 10; DNA METHYLATION; DNA PRIMERS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; LIVER NEOPLASMS; MALE; MEMBRANE PROTEINS; NUCLEAR PROTEINS; OVARIAN NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TESTICULAR NEOPLASMS;

EID: 67649408809     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.03.008     Document Type: Article

References (23)

1. Sánchez-Pulido L., Martín-Belmonte F., Valencia A., and Alonso M.A. MARVEL: a conserved domain involved in membrane apposition events. Trends Biochem. Sci. 27 (2002) 599-601
2. Puertollano R., and Alonso M.A. MAL, an integral element of the apical sorting machinery, is an itinerant protein that cycles between the trans-Golgi network and the plasma membrane. Mol. Biol. Cell 10 (1999) 3435-3447
3. Furuse M., Hirase T., Itoh M., Nagafuchi A., Yonemura S., Tsukita S., and Tsukita S. Occludin: a novel integral membrane proteins localizing at tight junctions. J. Cell Biol. 123 (1993) 1777-1788
4. Arthur C.P., and Stowell M.H. Structure of synaptophysin: a hexameric MARVEL-domain channel protein. Structure 15 (2007) 707-714
5. Jin C., Ding P., Wang Y., and Ma D. Regulation of EGF receptor signaling by the MARVEL domain-containing protein CKLFSF8. FEBS Lett. 579 (2005) 6375-6382
6. Zhong J., Wang Y., Qiu X., Mo X., Liu Y., Li T., Song Q., Ma D., and Han W. Characterization and expression profile of CMTM3/CKLFSF3. J. Biochem. Mol. Biol. 39 (2006) 537-545
7. Shao L., Cui Y., Li H., Liu Y., Zhao H., Wang Y., Zhang Y., Ng K.M., Han W., Ma D., and Tao Q. CMTM5 exhibits tumor suppressor activities and is frequently silenced by methylation in carcinoma cell lines. Clin. Cancer Res. 13 (2007) 5756-5762
8. Wang Y., Li T., Qiu X., Mo X., Zhang Y., Song Q., Ma D., and Han W. CMTM3 can affect the transcription activity of androgen receptor and inhibit the expression level of PSA in LNCaP cells. Biochem. Biophys. Res. Commun. 371 (2008) 54-58
9. Martín-Belmonte F., Martínez-Menárguez J.A., Aranda J.F., Ballesta J., de Marco M.C., and Alonso M.A. MAL regulates clathrin-mediated endocytosis at the apical surface of Madin-Darby canine kidney cells. J. Cell Biol. 163 (2003) 155-164
10. Han W., Lou Y., Tang J., Zhang Y., Chen Y., Li Y., Gu W., Huang J., Gui L., Tang Y., Li F., Song Q., Di C., Wang L., Shi Q., Sun R., Xia D., Rui M., Tang J., and Ma D. Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity. Biochem. J. 357 (2001) 127-135
11. Estrada B., Maeland A.D., Gisselbrecht S.S., Bloor J.W., Brown N.H., and Michelson A.M. The MARVEL domain protein, singles bar, is required for progression past the pre-fusion complex stage of myoblast fusion. Dev. Biol. 307 (2007) 328-339
12. Ikenouchi J., Sasaki H., Tsukita S., Furuse M., and Tsukita S. Loss of occludin affects tricellular localization of tricellulin. Mol. Biol. Cell 19 (2008) 4687-4693
13. Ikenouchi J., Furuse M., Furuse K., Sasaki H., Tsukita S., and Tsukita S. Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J. Cell Biol. 171 (2005) 939-945
14. Mimori K., Shiraishi T., Mashino K., Sonoda H., Yamashita K., Yoshinaga K., Masuda T., Utsunomiya T., Alonso M.A., Inoue H., and Mori M. MAL gene expression in esophageal cancer suppresses motility, invasion and tumorigenicity and enhances apoptosis through the Fas pathway. Oncogene 22 (2003) 3463-3471
15. Riazuddin S., Ahmed Z.M., Fanning A.S., Lagziel A., Kitajiri S., Ramzan K., Khan S.N., Chattaraj P., Friedman P.L., Anderson J.M., Belyantseva I.A., Forge A., Riazuddin S., and Friedman T.B. Tricellulin is a tight-junction protein necessary for hearing. Am. J. Hum. Genet. 79 (2006) 1040-1051
16. Hatada I., Fukasawa M., and Kimura M. Genome-wide profiling of promoter methylation in human. Oncogene 25 (2006) 3059-3064
17. Clement Q.J., Shareen M.L., and Bobby L.W. Gene expression profiling of human epidermal keratinocytes in simulated microgravity and recovery cultures. Geno. Prot. Bioinfo. 6 (2008) 8-28
18. Alves P.M., Lévy N., Stevenson B.J., Bouzourene H., Theiler G., Bricard G., Viatte S., Ayyoub M., Vuilleumier H., Givel J.C., Rimoldi D., Speiser D.E., Jongeneel C.V., Romero P.J., and Lévy F. Identification of tumor-associated antigens by large scale analysis of genes expressed in human colorectal cancer. Cancer Immun. 8 (2008) 11
19. Vagia T., Elena T., and Hara P. Optimized detection of circulating anti-nuclear envelope autoantibodies by immunofluorescence. BMC Immunol. 7 (2006) 20
20. Darchen F., Senyshyn J., Brondyk W.H., Taatjes D.J., Holz R.W., Henry J.P., Denizot J.P., and Macara I.G. The GTPase Rab3a is associated with large dense core vesicles in bovine chromaffin cells and rat PC12 cells. J. Cell Sci. 108 (1995) 1639-1649
21. Delettre C., Yuste V.J., Moubarak R.S., Bras M., Lesbordes-Brion J.C., Petres S., Bellalou J., and Susin S.A. AIFsh, a novel apoptosis-inducing factor (AIF) pro-apoptotic isoform with potential pathological relevance in human cancer. J. Biol. Chem. 281 (2006) 6413-6427
22. Fabbro M., and Henderson B.R. Regulation of tumor suppressors by nuclear-cytoplasmic shuttling. Exp. Cell Res. 282 (2003) 59-69
23. Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3 (2002) 415-428