Mitochondrial toxicity of the phyotochemicals daphnetoxin and daphnoretin - Relevance for possible anti-cancer application

Toxicology in Vitro

Volumn 23, Issue 5, 2009, Pages 772-779

  Diogo, Cátia V ^a   Félix, Luís ^b   Vilela, Sérgio ^b   Burgeiro, Ana ^a   Barbosa, Inês A ^a   Carvalho, Maria J M ^c   Oliveira, Paulo J ^a   Peixoto, Francisco P ^b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^c UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

Author keywords

Cancer cells; Daphnetoxin; Daphnoretin; Mitochondria; Toxicology

Indexed keywords

DAPHNETOXIN; DAPHNORETIN; DITERPENE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG SELECTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER MITOCHONDRION; MELANOMA; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TOXICITY; MOUSE; NONHUMAN; RAT; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; COUMARINS; DAPHNE; DOSE-RESPONSE RELATIONSHIP, DRUG; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; MELANOMA; MICE; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; RATS; RATS, WISTAR;

FABACEAE; RATTUS NORVEGICUS; RUTACEAE; THYMELAEACEAE;

EID: 67649401716     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.04.002     Document Type: Article

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