Differential binding to phospholipid bilayers modulates membrane-damaging activity of Naja naja atra cardiotoxins

Toxicon

Volumn 54, Issue 3, 2009, Pages 321-328

  Kao, Pei Hsiu ^a   Lin, Shinne Ren ^b   Chang, Long Sen ^a  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cardiotoxin; Membrane bound conformation; Membrane bound mode; Membrane damaging activity; Phospholipid component

Indexed keywords

CARDIOTOXIN; CARDIOTOXIN 1; CARDIOTOXIN 2; CARDIOTOXIN 3; CARDIOTOXIN 4; CARDIOTOXIN 5; CARDIOTOXIN N; DIMYRISTOYLPHOSPHATIDYLCHOLINE; PHOSPHATIDIC ACID; PHOSPHATIDYLCHOLINE; SNAKE VENOM; SPHINGOMYELIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BETA SHEET; BINDING AFFINITY; CONTROLLED STUDY; EGG YOLK; ERYTHROCYTE MEMBRANE; FLUORESCENCE; HEMOLYSIS; HUMAN; HUMAN CELL; MEMBRANE DAMAGE; NAJA NAJA ATRA; NONHUMAN; OXIDATION; PHOSPHOLIPID BILAYER; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN LIPID INTERACTION; PROTEIN SECONDARY STRUCTURE; SNAKE; STRUCTURE ANALYSIS; TOXIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CARDIOTOXINS; CELL MEMBRANE; CIRCULAR DICHROISM; COBRA; COBRA VENOMS; HUMANS; LIPID BILAYERS; MEMBRANE LIPIDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOLIPIDS; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID;

NAJA ATRA;

EID: 67649400324     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.04.024     Document Type: Article

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