-
1
-
-
0036580336
-
How pharmacokinetic and pharmacodynamic drug monitoring can improve outcome in solid organ transplant recipients
-
Klupp J, Holt DW, van Gelder T: How pharmacokinetic and pharmacodynamic drug monitoring can improve outcome in solid organ transplant recipients. Transpl Immunol 9: 211-214, 2002
-
(2002)
Transpl Immunol
, vol.9
, pp. 211-214
-
-
Klupp, J.1
Holt, D.W.2
van Gelder, T.3
-
3
-
-
0033571210
-
The temporal profile of calcineurin inhibition by cyclosporine in vivo
-
Halloran PF, Helms LM, Kung L, Noujaim J: The temporal profile of calcineurin inhibition by cyclosporine in vivo. Transplantation 68: 1356-1361, 1999
-
(1999)
Transplantation
, vol.68
, pp. 1356-1361
-
-
Halloran, P.F.1
Helms, L.M.2
Kung, L.3
Noujaim, J.4
-
4
-
-
8644226828
-
Low-dose cyclosporine with mycophenolate mofetil induces similar calcineurin activity and cytokine inhibition as does standard-dose cyclosporine in stable renal allografts
-
Grinyo JM, Cruzado JM, Millan O, Caldes A, Sabate I, Gil-Vernet S, Seron D, Brunet M, Campistol JM, Torras J, Martorell J: Low-dose cyclosporine with mycophenolate mofetil induces similar calcineurin activity and cytokine inhibition as does standard-dose cyclosporine in stable renal allografts. Transplantation 78: 1400-1403, 2004
-
(2004)
Transplantation
, vol.78
, pp. 1400-1403
-
-
Grinyo, J.M.1
Cruzado, J.M.2
Millan, O.3
Caldes, A.4
Sabate, I.5
Gil-Vernet, S.6
Seron, D.7
Brunet, M.8
Campistol, J.M.9
Torras, J.10
Martorell, J.11
-
5
-
-
0035664199
-
Non-radioactive determination of inosine 5′-monophosphate dehydrogenase (IMPDH) in peripheral mononuclear cells
-
Glander P, Braun KP, Hambach P, Bauer S, Mai I, Roots I, Waiser J, Fritsche L, Neumayer HH, Budde K: Non-radioactive determination of inosine 5′-monophosphate dehydrogenase (IMPDH) in peripheral mononuclear cells. Clin Biochem 34: 543-549, 2001
-
(2001)
Clin Biochem
, vol.34
, pp. 543-549
-
-
Glander, P.1
Braun, K.P.2
Hambach, P.3
Bauer, S.4
Mai, I.5
Roots, I.6
Waiser, J.7
Fritsche, L.8
Neumayer, H.H.9
Budde, K.10
-
6
-
-
0035400375
-
Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: Inhibition by immunosuppressive drugs in vitro
-
Barten MJ, Gummert JF, van Gelder T, Shorthouse R, Morris RE: Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: Inhibition by immunosuppressive drugs in vitro. J Immunol Methods 253: 95-112, 2001
-
(2001)
J Immunol Methods
, vol.253
, pp. 95-112
-
-
Barten, M.J.1
Gummert, J.F.2
van Gelder, T.3
Shorthouse, R.4
Morris, R.E.5
-
7
-
-
0036023133
-
Novel assays of multiple lymphocyte functions in whole blood measure: New mechanisms of action of mycophenolate mofetil in vivo
-
Barten MJ, van Gelder T, Gummert JF, Shorthouse R, Morris RE: Novel assays of multiple lymphocyte functions in whole blood measure: New mechanisms of action of mycophenolate mofetil in vivo. Transpl Immunol 10: 1-14, 2002
-
(2002)
Transpl Immunol
, vol.10
, pp. 1-14
-
-
Barten, M.J.1
van Gelder, T.2
Gummert, J.F.3
Shorthouse, R.4
Morris, R.E.5
-
8
-
-
33847167164
-
Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans
-
Bohler T, Nolting J, Kamar N, Gurragchaa P, Reisener K, Glander P, Neumayer HH, Budde K, Klupp J: Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans. Ther Drug Monit 29: 77-86, 2007
-
(2007)
Ther Drug Monit
, vol.29
, pp. 77-86
-
-
Bohler, T.1
Nolting, J.2
Kamar, N.3
Gurragchaa, P.4
Reisener, K.5
Glander, P.6
Neumayer, H.H.7
Budde, K.8
Klupp, J.9
-
9
-
-
10044283192
-
Pre-transplant inosine monophosphate dehydrogenase activity is associated with clinical outcome after renal transplantation
-
Glander P, Hambach P, Braun KP, Fritsche L, Giessing M, Mai I, Einecke G, Waiser J, Neumayer HH, Budde K: Pre-transplant inosine monophosphate dehydrogenase activity is associated with clinical outcome after renal transplantation. Am J Transplant 4: 2045-2051, 2004
-
(2004)
Am J Transplant
, vol.4
, pp. 2045-2051
-
-
Glander, P.1
Hambach, P.2
Braun, K.P.3
Fritsche, L.4
Giessing, M.5
Mai, I.6
Einecke, G.7
Waiser, J.8
Neumayer, H.H.9
Budde, K.10
-
10
-
-
0032732954
-
Pharmacodynamics of immunosuppression by mycophenolic acid: Inhibition of both lymphocyte proliferation and activation correlates with pharmacokinetics
-
Gummert JF, Barten MJ, Sherwood SW, van Gelder T, Morris RE: Pharmacodynamics of immunosuppression by mycophenolic acid: Inhibition of both lymphocyte proliferation and activation correlates with pharmacokinetics. J Pharmacol Exp Ther 291: 1100-1112, 1999
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 1100-1112
-
-
Gummert, J.F.1
Barten, M.J.2
Sherwood, S.W.3
van Gelder, T.4
Morris, R.E.5
-
11
-
-
0034667746
-
Pharmacodynamics of mycophenolic acid in heart allograft recipients: Correlation of lymphocyte proliferation and activation with pharmacokinetics and graft histology
-
Gummert JF, Barten MJ, van Gelder T, Billingham ME, Morris RE: Pharmacodynamics of mycophenolic acid in heart allograft recipients: Correlation of lymphocyte proliferation and activation with pharmacokinetics and graft histology. Transplantation 70: 1038-1049, 2000
-
(2000)
Transplantation
, vol.70
, pp. 1038-1049
-
-
Gummert, J.F.1
Barten, M.J.2
van Gelder, T.3
Billingham, M.E.4
Morris, R.E.5
-
12
-
-
0036766463
-
Pharmacodynamics of mycophenolate mofetil after heart transplantation: New mechanisms of action and correlations with histologic severity of graft rejection
-
Barten MJ, van Gelder T, Gummert JF, Boeke K, Shorthouse R, Billingham ME, Morris RE: Pharmacodynamics of mycophenolate mofetil after heart transplantation: New mechanisms of action and correlations with histologic severity of graft rejection. Am J Transplant 2: 719-732, 2002
-
(2002)
Am J Transplant
, vol.2
, pp. 719-732
-
-
Barten, M.J.1
van Gelder, T.2
Gummert, J.F.3
Boeke, K.4
Shorthouse, R.5
Billingham, M.E.6
Morris, R.E.7
-
13
-
-
1542617927
-
Sustained suppression of peripheral blood immune functions by treatment with mycophenolate mofetil correlates with reduced severity of cardiac allograft rejection
-
Klupp J, van Gelder T, Dambrin C, Regieli JJ, Boeke K, Billingham ME, Morris RE: Sustained suppression of peripheral blood immune functions by treatment with mycophenolate mofetil correlates with reduced severity of cardiac allograft rejection. J Heart Lung Transplant 23: 334-351, 2004
-
(2004)
J Heart Lung Transplant
, vol.23
, pp. 334-351
-
-
Klupp, J.1
van Gelder, T.2
Dambrin, C.3
Regieli, J.J.4
Boeke, K.5
Billingham, M.E.6
Morris, R.E.7
-
14
-
-
33846072003
-
Effect of mycophenolate mofetil monotherapy on T-cell functions and inosine monophosphate dehydrogenase activity in patients undergoing a kidney transplantation
-
Kamar N, Glander P, Nolting J, Bohler T, Hambach P, Liefeldt L, Neumayer HH, Klupp J, Budde K: Effect of mycophenolate mofetil monotherapy on T-cell functions and inosine monophosphate dehydrogenase activity in patients undergoing a kidney transplantation. Transplant Proc 38: 2292-2294, 2006
-
(2006)
Transplant Proc
, vol.38
, pp. 2292-2294
-
-
Kamar, N.1
Glander, P.2
Nolting, J.3
Bohler, T.4
Hambach, P.5
Liefeldt, L.6
Neumayer, H.H.7
Klupp, J.8
Budde, K.9
-
15
-
-
0036721788
-
Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis
-
Quemeneur L, Flacher M, Gerland LM, Ffrench M, Revillard JP, Bonnefoy-Berard N: Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis. J Immunol 169: 2747-2755, 2002
-
(2002)
J Immunol
, vol.169
, pp. 2747-2755
-
-
Quemeneur, L.1
Flacher, M.2
Gerland, L.M.3
Ffrench, M.4
Revillard, J.P.5
Bonnefoy-Berard, N.6
-
16
-
-
53749100278
-
Mycophenolate mofetil inhibits T-cell proliferation in kidney transplant recipients without lowering intracellular dGTP and GTP
-
Sankatsing SU, Prins JM, Yong SL, Roelofsen J, van Kuilenburg AB, Kewn S, Back DJ, Bemelman FJ, ten Berge IJ: Mycophenolate mofetil inhibits T-cell proliferation in kidney transplant recipients without lowering intracellular dGTP and GTP. Transpl Int 21: 1066-1071, 2008
-
(2008)
Transpl Int
, vol.21
, pp. 1066-1071
-
-
Sankatsing, S.U.1
Prins, J.M.2
Yong, S.L.3
Roelofsen, J.4
van Kuilenburg, A.B.5
Kewn, S.6
Back, D.J.7
Bemelman, F.J.8
ten Berge, I.J.9
-
17
-
-
60949112944
-
-
Bohler T, Canivet C, Le Nguyen PN, Galvani S, Thomsen, Durand D, Salvayre R, Nègre-Salvayre A, Rostaing L, Kamar, N: Cytokines correlate with age in healthy volunteers, dialysis patients and kidney -transplant patients. Cytokines 45: 169-173, 2009
-
Bohler T, Canivet C, Le Nguyen PN, Galvani S, Thomsen, Durand D, Salvayre R, Nègre-Salvayre A, Rostaing L, Kamar, N: Cytokines correlate with age in healthy volunteers, dialysis patients and kidney -transplant patients. Cytokines 45: 169-173, 2009
-
-
-
-
18
-
-
0028941099
-
The critical glycosylation site of human transferrin receptor contains a high-mannose oligosaccharide
-
Hayes GR, Williams A, Costello CE, Enns CA, Lucas JJ: The critical glycosylation site of human transferrin receptor contains a high-mannose oligosaccharide. Glycobiology 5: 227-232, 1995
-
(1995)
Glycobiology
, vol.5
, pp. 227-232
-
-
Hayes, G.R.1
Williams, A.2
Costello, C.E.3
Enns, C.A.4
Lucas, J.J.5
-
19
-
-
0030071890
-
Mycophenolic acid suppresses protein N-linked glycosylation in human monocytes and their adhesion to endothelial cells and to some substrates
-
Laurent AF, Dumont S, Poindron P, Muller CD: Mycophenolic acid suppresses protein N-linked glycosylation in human monocytes and their adhesion to endothelial cells and to some substrates. Exp Hematol 24: 59-67, 1996
-
(1996)
Exp Hematol
, vol.24
, pp. 59-67
-
-
Laurent, A.F.1
Dumont, S.2
Poindron, P.3
Muller, C.D.4
-
20
-
-
0028998724
-
GTP depletion induced by IMP dehydrogenase inhibitors blocks RNA-primed DNA synthesis
-
Catapano CV, Dayton JS, Mitchell BS, Fernandes DJ: GTP depletion induced by IMP dehydrogenase inhibitors blocks RNA-primed DNA synthesis. Mol Pharmacol 47: 948-955, 1995
-
(1995)
Mol Pharmacol
, vol.47
, pp. 948-955
-
-
Catapano, C.V.1
Dayton, J.S.2
Mitchell, B.S.3
Fernandes, D.J.4
-
21
-
-
0023153124
-
GTP dependence of the transduction of mitogenic signals through the T3 complex in T lymphocytes indicates the involvement of a G-protein
-
Mustelin T: GTP dependence of the transduction of mitogenic signals through the T3 complex in T lymphocytes indicates the involvement of a G-protein. FEBS Lett 213: 199-203, 1987
-
(1987)
FEBS Lett
, vol.213
, pp. 199-203
-
-
Mustelin, T.1
-
22
-
-
0028004196
-
Novel mechanisms of brequinar sodium immunosuppression on T cell activation
-
Forrest TL, Ware RE, Howard T, Jaffee BD, Denning SM: Novel mechanisms of brequinar sodium immunosuppression on T cell activation. Transplantation 58: 920-926, 1994
-
(1994)
Transplantation
, vol.58
, pp. 920-926
-
-
Forrest, T.L.1
Ware, R.E.2
Howard, T.3
Jaffee, B.D.4
Denning, S.M.5
-
23
-
-
0029585361
-
Importance of ribonucleotide availability to proliferating T-lymphocytes from healthy humans. Disproportionate expansion of pyrimidine pools and contrasting effects of de novo synthesis inhibitors
-
Fairbanks LD, Bofill M, Ruckemann K, Simmonds HA: Importance of ribonucleotide availability to proliferating T-lymphocytes from healthy humans. Disproportionate expansion of pyrimidine pools and contrasting effects of de novo synthesis inhibitors. J Biol Chem 270: 29682-29689, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 29682-29689
-
-
Fairbanks, L.D.1
Bofill, M.2
Ruckemann, K.3
Simmonds, H.A.4
-
24
-
-
0034654108
-
Mycophenolic acid-induced GTP depletion also affects ATP and pyrimidine synthesis in mitogen-stimulated primary human Tlymphocytes
-
Qiu Y, Fairbanks LD, Ruckermann K, Hawrlowicz CM, Richards DF, Kirschbaum B, Simmonds HA: Mycophenolic acid-induced GTP depletion also affects ATP and pyrimidine synthesis in mitogen-stimulated primary human Tlymphocytes. Transplantation 69: 890-897, 2000
-
(2000)
Transplantation
, vol.69
, pp. 890-897
-
-
Qiu, Y.1
Fairbanks, L.D.2
Ruckermann, K.3
Hawrlowicz, C.M.4
Richards, D.F.5
Kirschbaum, B.6
Simmonds, H.A.7
-
25
-
-
0141996252
-
Effect of mycophenolate mofetil on IMP dehydrogenase after the first dose and after long-term treatment in renal transplant recipients
-
Glander P, Hambach P, Braun KP, Fritsche L, Waiser J, Mai I, Neumayer HH, Budde K: Effect of mycophenolate mofetil on IMP dehydrogenase after the first dose and after long-term treatment in renal transplant recipients. Int J Clin Pharmacol Ther 41: 470-476, 2003
-
(2003)
Int J Clin Pharmacol Ther
, vol.41
, pp. 470-476
-
-
Glander, P.1
Hambach, P.2
Braun, K.P.3
Fritsche, L.4
Waiser, J.5
Mai, I.6
Neumayer, H.H.7
Budde, K.8
-
26
-
-
0035993723
-
Pharmacodynamic monitoring of mycophenolate mofetil in stable renal allograft recipients
-
Budde K, Braun KP, Glander P, Bohler T, Hambach P, Fritsche L, Waiser J, Mai I, Neumayer HH: Pharmacodynamic monitoring of mycophenolate mofetil in stable renal allograft recipients. Transplant Proc 34: 1748-1750, 2002
-
(2002)
Transplant Proc
, vol.34
, pp. 1748-1750
-
-
Budde, K.1
Braun, K.P.2
Glander, P.3
Bohler, T.4
Hambach, P.5
Fritsche, L.6
Waiser, J.7
Mai, I.8
Neumayer, H.H.9
-
27
-
-
0035677974
-
Pharmacodynamic monitoring of mycophenolate mofetil in renal allograft recipients
-
Budde K, Glander P, Braun KP, Bohler T, Waiser J, Fritsche L, Mai I, Neumayer H: Pharmacodynamic monitoring of mycophenolate mofetil in renal allograft recipients. Transplant Proc 33: 3313-3315, 2001
-
(2001)
Transplant Proc
, vol.33
, pp. 3313-3315
-
-
Budde, K.1
Glander, P.2
Braun, K.P.3
Bohler, T.4
Waiser, J.5
Fritsche, L.6
Mai, I.7
Neumayer, H.8
-
28
-
-
0029812955
-
Pharmacodynamic assessment of mycophenolic acid-induced immunosuppression in renal transplant recipients
-
Langman LJ, LeGatt DF, Halloran PF, Yatscoff RW: Pharmacodynamic assessment of mycophenolic acid-induced immunosuppression in renal transplant recipients. Transplantation 62: 666-672, 1996
-
(1996)
Transplantation
, vol.62
, pp. 666-672
-
-
Langman, L.J.1
LeGatt, D.F.2
Halloran, P.F.3
Yatscoff, R.W.4
-
29
-
-
32344446094
-
Inosine monophosphate dehydrogenase activity in renal allograft recipients during mycophenolate treatment
-
Vethe NT, Mandla R, Line PD, Midtvedt K, Hartmann A, Bergan S: Inosine monophosphate dehydrogenase activity in renal allograft recipients during mycophenolate treatment. Scand J Clin Lab Invest 66: 31-44, 2006
-
(2006)
Scand J Clin Lab Invest
, vol.66
, pp. 31-44
-
-
Vethe, N.T.1
Mandla, R.2
Line, P.D.3
Midtvedt, K.4
Hartmann, A.5
Bergan, S.6
|