Electrical activity and exocytotic correlates of biphasic insulin secretion from β-cells of canine islets of Langerhans: Contribution of tuning two modes of Ca2+ entry-dependent exocytosis to two modes of glucose-induced electrical activity

Channels

Volumn 3, Issue 3, 2009, Pages 181-193

  Misler, Stanley ^a   Zhou, Zhuan ^a,b   Dickey, Adam S ^a,c   Silva, Amelia M ^a,d   Pressel, David M ^a,e   Barnett, David W ^a,f  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PEKING UNIVERSITY   (China)

^c UNIVERSITY OF CHICAGO   (United States)

^d UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^e NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

^f Saint Louis University   (United States)

Author keywords

Amperometry; Biphasic insulin secretion; Membrane capacitance; Phasic exocytosis; Tonic exocytosis; cell exocytosis; cell heterogeneity

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; FORSKOLIN; GLUCOSE; INSULIN; POTASSIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL; CALCIUM; CALCIUM CHANNEL;

ACTION POTENTIAL; AMPEROMETRY; ANIMAL CELL; ARTICLE; BIPHASIC INSULIN SECRETION; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CHANNEL GATING; CONTROLLED STUDY; CORRELATION ANALYSIS; DOG; ELECTRIC CAPACITANCE; EXOCYTOSIS; GLUCOSE METABOLISM; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PATCH CLAMP; PLATEAU DEPOLARIZATION; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; CYTOLOGY; METABOLISM; PHYSIOLOGY; SECRETION; SECRETORY VESICLE;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CELLS, CULTURED; DOGS; EXOCYTOSIS; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; MEMBRANE POTENTIALS; SECRETORY VESICLES;

EID: 67649383363     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.3.3.8972     Document Type: Article

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