Fast and automated large-area imaging MALDI mass spectrometry in microprobe and microscope mode

International Journal of Mass Spectrometry

Volumn 285, Issue 1-2, 2009, Pages 19-25

  Klerk, Leendert A ^a   Altelaar, A F Maarten ^a   Froesch, Martin ^a   McDonnell, Liam A ^a   Heeren, Ron M A ^a  

^a FOM INSTITUTE AMOLF   (Netherlands)

Author keywords

MALDI; Microscope imaging mass spectrometry; TRIFT

Indexed keywords

EID: 67649363297     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2009.02.032     Document Type: Article

References (25)

1. Hillenkamp F., Karas M., Beavis R.C., and Chait B.T. Matrix-assisted laser desorption ionization mass-spectrometry of biopolymers. Analytical Chemistry 63 (1991) A1193
2. Karas M., Bachmann D., Bahr U., and Hillenkamp F. Matrix-assisted ultraviolet laser desorption of non-volatile compounds. International Journal of Mass Spectrometry 78 (1987) 53
3. Stahl B., Linos A., Karas M., Hillenkamp F., and Steup M. Analysis of fructans from higher plants by matrix-assisted laser desorption/ionization mass spectrometry. Analytical Biochemistry 246 (1997) 195
4. Montaudo G., Samperi F., and Montaudo M.S. Characterization of synthetic polymers by MALDI-MS. Progress in Polymer Science 31 (2006) 277
5. Dekoster C.G., Duursma M.C., Vanrooij G.J., Heeren R.M.A., and Boon J.J. Endgroup analysis of polyethylene-glycol polymers by matrix-assisted laser-desorption ionization Fourier-transform ion-cyclotron resonance mass-spectrometry. Rapid Communications in Mass Spectrometry 9 (1995) 957
6. Griesser H.J., Kingshott P., McArthur S.L., McLean K.M., Kinsel G.R., and Timmons R.B.R.B. Surface-MALDI mass spectrometry in biomaterials research. Biomaterials 25 (2004) 4861
7. Jasminka Godovac-Zimmermann L.R.B. Perspectives for mass spectrometry and functional proteomics. Mass Spectrometry Reviews 20 (2001) 1
8. McDonnell L.A., and Heeren R.M.A. Imaging mass spectrometry. Mass Spectrometry Reviews 26 (2007) 606
9. Cornett D.S., Reyzer M.L., Chaurand P., and Caprioli R.M. MALDI imaging mass spectrometry: molecular snapshots of biochemical systems. Nature Methods 4 (2007) 828
10. Stoeckli M., Staab D., and Schweitzer A. Compound and metabolite distribution measured by MALDI mass spectrometric imaging in whole-body tissue sections. International Journal of Mass Spectrometry Imaging Mass Spectrometry Special Issue 260 (2007) 195
11. Khatib-Shahidi S., Andersson M., Herman J.L., Gillespie T.A., and Caprioli R.M. Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry. Analytical Chemistry 78 (2006) 6448
12. Jurchen J.C., Rubakhin S.S., and Sweedler J.V. MALDI-MS imaging of features smaller than the size of the laser beam. Journal of the American Society for Mass Spectrometry 16 (2005) 1654
13. Altelaar A.F., Luxembourg S.L., McDonnell L.A., Piersma S.R., and Heeren R.M. Imaging mass spectrometry at cellular length scales. Natural Protocol 2 (2007) 1185
14. McDonnell L.A., Piersma S.R., Altelaar A.F.M., Mize T.H., Luxembourg S.L., Verhaert P.D.E.M., van Minnen J., and Heeren R.M.A. Subcellular imaging mass spectrometry of brain tissue. Journal of Mass Spectrometry 40 (2005) 160
15. Spengler B., and Hubert M. Scanning microprobe matrix-assisted laser desorption ionization (SMALDI) mass spectrometry: instrumentation for sub-micrometer resolved LDI and MALDI surface analysis. Journal of the American Society for Mass Spectrometry 13 (2002) 735
16. Dreisewerd K., Schurenberg M., Karas M., and Hillenkamp F. Influence of the laser intensity and spot size on the desorption of molecules and ions in matrix-assisted laser-desorption ionization with a uniform beam profile. International Journal of Mass Spectrometer 141 (1995) 127
17. Luxembourg S.L., Mize T.H., McDonnell L.A., and Heeren R.M.A. High-spatial resolution mass spectrometric imaging of peptide and protein distributions on a surface. Analytical Chemistry 76 (2004) 5339
18. Ingendoh A., Karas M., Killenkamp F., and Giessmann U. Factors affecting the resolution in matrix-assisted laser-desorption ionization mass-spectrometry. International Journal of Mass Spectrometry 131 (1994) 345
19. Altelaar A.F.M., Taban I.M., McDonnell L.A., Verhaert P.D.E.M., de Lange R.P.J., Adan R.A.H., Mooi W.J., Heeren R.M.A., and Piersma S.R. High-resolution MALDI imaging mass spectrometry allows localization of peptide distributions at cellular length scales in pituitary tissue sections. International Journal of Mass Spectrometry 260 (2007) 203
20. Altelaar A.F.M., Klinkert I., Jalink K., de Lange R.P.J., Adan R.A.H., Heeren R.M.A., and Piersma S.R. Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry. Analytical Chemistry 78 (2006) 734
21. Klinkert I., McDonnell L.A., Luxembourg S.L., Altelaar A.F.M., Amstalden E.R., Piersma S.R., and Heeren R.M.A. Tools and strategies for visualization of large image data sets in high-resolution imaging mass spectrometry. Review of Scientific Instruments 78 (2007) 053716
22. Vickerman J.C.B., and David. ToF-SIMS: Surface Analysis by Mass Spectrometry (2001), IM Publications and SurfaceSpectra Ltd.
23. Meier R., and Eberhardt P. Velocity and ion species dependence of the gain of microchannel plates. International Journal of Mass Spectrometry 123 (1993) 19
24. Ens Y.M.W., Mayer F., and Standing K.G. Properties of matrix-assisted laser desorption. Measurements with a time-to-digital converter. Rapid Communications in Mass Spectrometry 5 (1991) 117
25. M. Stoeckli, D. Staab, S. Capretta, Automated Matrix Deposition for MALDI MSI, 54th ASMS Conference on Mass Spectrometry and Allied Topics, Seattle, WA, 2006.