Topical and transdermal drug products

Pharmacopeial Forum

Volumn 35, Issue 3, 2009, Pages 750-764

  Marques, Margareth ^a   Ueda, Clarence T ^b   Shah, Vinod P ^b   Derdzinski, Kris ^b   Ewing, Gary ^b   Flynn, Gordon ^b   Maibach, Howard ^b   Rytting, Howard ^b   Shaw, Steve ^b   Thakker, Kailas ^b   Yacobi, Avi ^b  

^a UNITED STATES PHARMACOPEIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; TOPICAL AGENT;

DRUG ADMINISTRATION ROUTE; DRUG DETERMINATION; DRUG DOSAGE FORM; DRUG IDENTIFICATION; DRUG IMPURITY; DRUG QUALITY; DRUG RELEASE; DRUG SCREENING; DRUG STABILITY; DRUG STERILITY; EQUIPMENT DESIGN; PADDLE OVER DISK METHOD; RECIPROCATING HOLDER METHOD; REVIEW; ROTATING CYLINDER METHOD; SCREENING TEST; SKIN; TRANSDERMAL PATCH; VERTICAL DIFFUSION CELL METHOD;

EID: 67649354606     PISSN: 03634655     EISSN: 15421945     Source Type: Journal    
DOI: None     Document Type: Review

References (7)

1. Disk assembly (stainless support disk) is available from www.millipore.com.
2. A suitable device is the watchglass-patch-polytef mesh sandwich assembly available as the Transdermal Sandwich from www.hansonresearch.com.
3. Use Dow Corning, MD7-4502 Silicone Adhesive 65% in ethyl acetate, or the equivalent.
4. Use Cuprophan, Type 150 pm, 11 ± 0.5-nm thick, an inert, porous cellulosic material, which is available from www.medicell.co.uk or www.varianinc.com.
5. The cylinder stirring element is available from www.varianinc.com.
6. The materials should not sorb, react with, or interfere with the specimen being tested.
7. The reciprocating disk sample holder is available at www.varianinc.com.