Neuropsychological functions and metabolic aspects in subclinical hypothyroidism: The effects of l-thyroxine

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 33, Issue 5, 2009, Pages 854-859

  Baldini, Marina ^a   Colasanti, Alessandro ^a   Orsatti, Alessandra ^b   Airaghi, Lorena ^a   Mauri, Massimo C ^a   Cappellini, Maria Domenica ^a  

^a FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Health status; Neuropsychological functions; Subclinical hypothyroidism

Indexed keywords

LEVOTHYROXINE; LIOTHYRONINE;

ADULT; AGED; ARTICLE; ATTENTION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; GLUCOSE METABOLISM; GOITER; HEALTH BEHAVIOR; HEALTH STATUS; HUMAN; HYPOTHYROIDISM; LIPID METABOLISM; MENTAL FUNCTION; NEUROPSYCHOLOGICAL TEST; SHORT FORM 36;

ADULT; AGED; ENERGY METABOLISM; FEMALE; HUMANS; HYPOTHYROIDISM; LIPID METABOLISM; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; REACTION TIME; STEREOISOMERISM; THYROXINE;

EID: 67649354044     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2009.04.009     Document Type: Article

References (46)

1. Anckarsater R., Zetterberg H., Blennow K., and Anckarsater H. Association between thyroid hormone levels and monoaminergic neurotransmission during surgery. Psychoneuroendocrinology 32 (2007) 1138-1143
2. Andersen S., Pedersen K.M., Bruun N.H., and Laurberg P. Narrow individual variations in serum T(4) and T(3) in normal subjects: a clue to the understanding of subclinical thyroid disease. J Clin Endocrinol Metab 87 (2002) 1068-1072
3. Arinzon Z., Zuta A., Peisakh A., Feldman J., and Berner Y. Evaluation response and effectiveness of thyroid hormone replacement treatment on lipid profile and function in elderly patients with subclinical hypothyroidism. Arch Gerontol Geriatr 44 (2007) 13-19
4. Baldini I.M., Vita A., Mauri M.C., Amodei V., Carrisi M., Bravin S., and Cantalamessa L. Pychopathological and cognitive features in subclinical hypothyroidism. Prog Neuropsychopharmacol Biol Psychiatry 21 (1997) 925-935
5. Bauer M., Heinz A., and Whybrow P.C. Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain. Mol Psychiatry 7 (2002) 140-156
6. Bell R.J., Rivera-Woll L., Davison S., Topliss D.J., Donath S., and Davis S.R. Well-being, health-related quality of life and cardiovascular disease risk profile in women with subclinical thyroid disease - a community-based study. Clin Endocrinol (Oxf) 66 (2007) 548-556
7. Biondi B., and Cooper D.S. The clinical significance of subclinical thyroid dysfunction. Endocr Rev 29 (2008) 76-131
8. Bono G., Fancellu R., Blandini F., Santoro G., and Mauri M. Cognitive and affective status in mild hypothyroidism and interactions with l-thyroxine treatment. Acta Neurol Scand 110 (2004) 59-66
9. Brucker-Davis F., Thayer K., and Colborn T. Significant effects of mild endogenous hormonal changes in humans: considerations for low-dose testing. Environ Health Perspect 109 Suppl 1 (2001) 21-26
10. Canaris G.J., Manowitz N.R., Mayor G., and Ridgway E.C. The Colorado thyroid disease prevalence study. Arch Intern Med 160 (2000) 526-534
11. Danese M.D., Ladenson P.W., Meinert C.L., and Powe N.R. Clinical review 115: effect of thyroxine therapy on serum lipoproteins in patients with mild thyroid failure: a quantitative review of the literature. J Clin Endocrinol Metab 85 (2000) 2993-3001
12. Davis J.D., Stern R.A., and Flashman L.A. Cognitive and neuropsychiatric aspects of subclinical hypothyroidism: significance in the elderly. Curr Psychiatry Rep 5 (2003) 384-390
13. Davis J.D., and Tremont G. Neuropsychiatric aspects of hypothyroidism and treatment reversibility. Minerva Endocrinol 32 (2007) 49-65
14. Evans K.R., Sills T., DeBrota D.J., Gelwicks S., Engelhardt N., and Santor D. An item response analysis of the Hamilton Depression Rating Scale using shared data from two pharmaceutical companies. J Psychiatr Res 38 (2004) 275-284
15. Fitzpatrick R., Fletcher A., Gore S., Jones D., Spiegelhalter D., and Cox D. Quality of life measures in health care. I: Applications and issues in assessment. BMJ 305 (1992) 1074-1077
16. Gharib H., Tuttle R.M., Baskin H.J., Fish L.H., Singer P.A., and Mcdermott M.T. Subclinical thyroid dysfunction: a joint statement on management from the American Association of Clinical Endocrinologists, the American Thyroid Association, and the Endocrine Society. J Clin Endocrinol Metab 90 (2005) 581-585
17. Gordon J.T., Kaminski D.M., Rozanov C.B., and Dratman M.B. Evidence that 3,3',5-triiodothyronine is concentrated in and delivered from the locus coeruleus to its noradrenergic targets via anterograde axonal transport. Neuroscience 93 (1999) 943-954
18. Gulseren S., Gulseren L., Hekimsoy Z., Cetinay P., Ozen C., and Tokatlioglu B. Depression, anxiety, health-related quality of life, and disability in patients with overt and subclinical thyroid dysfunction. Arch Med Res 37 (2006) 133-139
19. Gussekloo J., van Exel E., De Craen A.J., Meinders A.E., Frolich M., and Westendorp R.G. Thyroid status, disability and cognitive function, and survival in old age. Jama 292 (2004) 2591-2599
20. Hak A.E., Pols H.A., Visser T.J., Drexhage H.A., Hofman A., and Witteman J.C. Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam Study. Ann Intern Med 132 (2000) 270-278
21. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol 32 (1959) 50-55
22. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 23 (1960) 56-62
23. Jenkinson C., Coulter A., and Wright L. Short form 36 (SF36) health survey questionnaire: normative data for adults of working age. Bmj 306 (1993) 1437-1440
24. Jensovsky J., Ruzicka E., Spackova N., and Hejdukova B. Changes of event related potential and cognitive processes in patients with subclinical hypothyroidism after thyroxine treatment. Endocr Regul 36 (2002) 115-122
25. Jorde R., Waterloo K., Storhaug H., Nyrnes A., Sundsfjord J., and Jenssen T.G. Neuropsychological function and symptoms in subjects with subclinical hypothyroidism and the effect of thyroxine treatment. J Clin Endocrinol Metab 91 (2006) 145-153
26. Kong W.M., Sheikh M.H., Lumb P.J., Naoumova R.P., Freedman D.B., Crook M., et al. A 6-month randomized trial of thyroxine treatment in women with mild subclinical hypothyroidism. Am J Med 112 (2002) 348-354
27. Lifschytz T., Segman R., Shalom G., Lerer B., Gur E., Golzer T., and Newman M.E. Basic mechanisms of augmentation of antidepressant effects with thyroid hormone. Curr Drug Targets 7 (2006) 203-210
28. Lindeman R.D., Schade D.S., Larue A., Romero L.J., Liang H.C., Baumgartner R.N., et al. Subclinical hypothyroidism in a biethnic, urban community. J Am Geriatr Soc 47 (1999) 703-709
29. Mauri M.C., Gianetti S., Pugnetti L., and Altamura A.C. Quazepam versus triazolam in patients with sleep disorders: a double-blind study. Int J Clin Pharmacol Res 13 (1993) 173-177
30. Meier C., Staub J.J., Roth C.B., Guglielmetti M., Kunz M., Miserez A.R., et al. TSH-controlled l-thyroxine therapy reduces cholesterol levels and clinical symptoms in subclinical hypothyroidism: a double blind, placebo-controlled trial (Basel Thyroid Study). J Clin Endocrinol Metab 86 (2001) 4860-4866
31. Monti M, Bellini A, Tosi E. Un apparato elettronico per la determinazione collettiva dei tempi di reazione. Ing Ferroviaria 1964;6:1-12.
32. Ochs N., Auer R., Bauer D.C., Nanchen D., Gussekloo J., Cornuz J., and Rodondi N. Meta-analysis: subclinical thyroid dysfunction and the risk for coronary heart disease and mortality. Ann Intern Med 148 (2008) 832-845
33. Parle J.V., Maisonneuve P., Sheppard M.C., Boyle P., and Franklyn J.A. Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study. Lancet 358 (2001) 861-865
34. Razvi S., Ingoe L., Keeka G., Oates C., Mcmillan C., and Weaver J.U. The beneficial effect of l-thyroxine on cardiovascular risk factors, endothelial function, and quality of life in subclinical hypothyroidism: randomized, crossover trial. J Clin Endocrinol Metab 92 (2007) 1715-1723
35. Razvi S., McMillan C.V., and Weaver J.U. Instruments used in measuring symptoms, health status and quality of life in hypothyroidism: a systematic qualitative review. Clin Endocrinol (Oxf) 63 (2005) 617-624
36. Razvi S., Shakoor A., Vanderpump M., Weaver J.U., and Pearce S.H. The influence of age on the relationship between subclinical hypothyroidism and ischemic heart disease: a metaanalysis. J Clin Endocrinol Metab 93 (2008) 2998-3007
37. Roberts L.M., Pattison H., Roalfe A., Franklyn J., Wilson S., Hobbs F.D., and Parle J.V. Is subclinical thyroid dysfunction in the elderly associated with depression or cognitive dysfunction?. Ann Intern Med 145 (2006) 573-581
38. Rodondi N., Bauer D.C., Cappola A.R., Cornuz J., Robbins J., Fried L.P., et al. Subclinical thyroid dysfunction, cardiac function, and the risk of heart failure. The Cardiovascular Health study. J Am Coll Cardiol 52 (2008) 1152-1159
39. Saravanan P., Visser T.J., and Dayan C.M. Psychological well-being correlates with free thyroxine but not free 3,5,3′-triiodothyronine levels in patients on thyroid hormone replacement. J Clin Endocrinol Metab 91 (2006) 3389-3393
40. Surks M.I., Ortiz E., Daniels G.H., Sawin C.T., Col N.F., Cobin R.H., et al. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. Jama 291 (2004) 228-238
41. Vanderpump M.P., Tunbridge W.M., French J.M., Appleton D., Bates D., Clark F., et al. The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clin Endocrinol (Oxf) 43 1 (1995) 55-68
42. Walsh J.P., Bremner A.P., Bulsara M.K., O'leary P., Leedman P.J., Feddema P., and Michelangeli V. Thyroid dysfunction and serum lipids: a community-based study. Clin Endocrinol (Oxf) 63 (2005) 670-675
43. Watt T., Groenvold M., Rasmussen A.K., Bonnema S.J., Hegedus L., Bjorner J.B., and Feldt-Rasmussen U. Quality of life in patients with benign thyroid disorders. A review. Eur J Endocrinol 154 (2006) 501-510
44. Wechsler D. Wais-R. Wechsler Adult Intelligence Scale, Revised. Manuale, Adattamento Italiano (2003), Edizioni Giunti OS, Firenze
45. Zhu D.F., Wang Z.X., Zhang D.R., Pan Z.L., He S., Hu X.P., et al. fMRI revealed neural substrate for reversible working memory dysfunction in subclinical hypothyroidism. Brain 129 (2006) 2923-2930
46. Zulewski H., Muller B., Exer P., Miserez A.R., and Staub J.J. Estimation of tissue hypothyroidism by a new clinical score: evaluation of patients with various grades of hypothyroidism and controls. J Clin Endocrinol Metab 82 (1997) 771-776