The influence of surface morphology and rigidity of the substrata on cell motility

Materials Letters

Volumn 63, Issue 21, 2009, Pages 1872-1875

  Chen, Chien Chang ^a,b   Hsieh, Patrick Chin Ho ^a   Wang, Guo Ming ^a   Chen, Wen Chi ^a   Yeh, Ming Long ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

Author keywords

Cell motility; Directional movement; MEMS; PDMS; Substrate rigidity; Surface morphology

Indexed keywords

CELL IMAGES; CELL MOTILITY; CELL MOVEMENT; CONTROL GROUPS; DIRECTIONAL MOVEMENT; MELANOMA CELLS; MICROELECTROMECHANICAL SYSTEMS; PDMS; POLYDIMETHYLSILOXANE PDMS; SURFACE PATTERN;

CELL MEMBRANES; COMPOSITE MICROMECHANICS; CYTOLOGY; GLASS; MEMS; MICROCHANNELS; MORPHOLOGY; RIGIDITY; SILICONES; STIFFNESS; SUBSTRATES;

SURFACE MORPHOLOGY;

EID: 67649353871     PISSN: 0167577X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.matlet.2009.05.073     Document Type: Article

References (13)

1. Horwitz R., and Webb D. Cell migration. Curr Biol 13 (2003) R756-759
2. Lo C.M., Wang H.B., Dembo M., and Wang Y.L. Cell movement is guided by the rigidity of the substrate. Biophys J 79 (2000) 144-152
3. Curtis A.S., Casey B., Gallagher J.O., Pasqui D., Wood M.A., and Wilkinson C.D. Substratum nanotopography and the adhesion of biological cells. Are symmetry or regularity of nanotopography important?. Biophys Chem 94 (2001) 275-283
4. Ghosh K., Pan Z., Guan E., Ge S., Liu Y., Nakamura T., et al. Cell adaptation to a physiologically relevant ECM mimic with different viscoelastic properties. Biomaterials 28 (2007) 671-679
5. Allen L.T., Fox E.J., Blute I., Kelly Z.D., Rochev Y., Keenan A.K., et al. Interaction of soft condensed materials with living cells: phenotype/transcriptome correlations for the hydrophobic effect. Proc Natl Acad Sci U S A 100 (2003) 6331-6336
6. Sniadecki N.J., Desai R.A., Ruiz S.A., and Chen C.S. Nanotechnology for cell-substrate interactions. Ann Biomed Eng 34 (2006) 59-74
7. Wang J., Hong B., Kai J., Han J., Zou Z., Ahn C.h., et al. Mini sensing chip for point-of-care acute myocardial infarction diagnosis utilizing micro-electro-mechanical system and nano-technology. Adv Exp Med Biol 645 (2009) 101-107
8. Sneddon I.N. The relation between load and penetration in the axisymmetric Boussinesq problem for a punch of arbitrary profile. Int J Eng Sci 3 (1965) 47-57
9. Dalton B.A., Walboomers X.F., Dziegielewski M., Evans M.D., Taylor S., Jansen J.A., et al. Modulation of epithelial tissue and cell migration by microgrooves. J Biomed Mater Res 56 (2001) 195-207
10. Stothard B.W., Madeja Z., Korohoda W., Curtis A., and Wilkinson C. Activation of macrophage-like cells by multiple grooved substrata. Topographical control of cell behaviour. Cell Biol Int 19 (1995) 485-490
11. Lauffenburger D.A., and Horwitz A.F. Cell migration: a physically integrated molecular process. Cell 84 (1996) 359-369
12. Cavalcanti-Adam E.A., Volberg T., Micoulet A., Kessler H., Geiger B., and Spatz J.P. Cell spreading and focal adhesion dynamics are regulated by spacing of integrin ligands. Biophys J 92 (2007) 2964-2974
13. Sheetz M.P., Felsenfeld D.P., and Galbraith C.G. Cell migration: regulation of force on extracellular-matrix integrin complexes. Trends Cell Biol 8 (1998) 51-54