Isolation and characterisation of an anticoagulant oligopeptide from blue mussel, Mytilus edulis

Food Chemistry

Volumn 117, Issue 4, 2009, Pages 687-692

  Jung, Won Kyo ^a   Kim, Se Kwon ^b  

^a Chosun University   (South Korea)

^b Pukyong National University   (South Korea)

Author keywords

Anticoagulant peptide; Blood clotting time; Blue mussel; Intrinsic tenase complex; Mytilus edulis; Prothrombinase complex

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 9; CALMODULIN; INTRINSIC FACTOR; INTRINSIC FACTOR TENASE; MYTILUS EDULIS ANTICOAGULANT PEPTIDE; PROTHROMBIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BLOOD CLOTTING; CHEMICAL STRUCTURE; DOSE RESPONSE; DRUG MECHANISM; ISOLATION PROCEDURE; MOLECULAR WEIGHT; MUSSEL; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PROTEIN DEGRADATION; SCALLOP; THROMBIN TIME;

MYTILUS EDULIS;

EID: 67649336586     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodchem.2009.04.077     Document Type: Article

References (15)

1. Bauer K.A. Activation of the factor VII-tissue factor pathway. Thrombosis and Haemostasis 78 1 (1997) 108-111
2. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 (1976) 248-254
3. Butenas S., van't Veer C., and Mann K.G. Evaluation of the initiation phase of blood coagulation using ultrasensitive assays for serine proteases. Journal of Biological Chemistry 272 (1997) 21527-21533
4. Davie E.W., Fujikawa K., and Kisel W. The coagulation cascade: Initiation, maintenance, and regulation. Biochemistry 30 43 (1991) 10363-10370
5. Jung W.K., Je J.Y., Kim H.J., and Kim S.K. A novel anticoagulant protein from Scapharca broughtonii. Journal of Biochemistry and Molecular Biology 35 2 (2001) 199-205
6. Koyama T., Noguchi K., Aniya Y., and Sakanashi M. Analysis for sites of anticoagulant action of plancinin, a new anticoagulant peptide isolated from the starfish Acanthaster planci, in the blood coagulation cascade. General Pharmacology 31 2 (1998) 277-282
7. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
8. Luchtman-Jones L., and Broze Jr. G.J. The current status of coagulation. Annals of Medicine 27 (1995) 47-52
9. Mann K.G. Prothrombin. Methods in Enzymology 45 (1976) 123-156
10. Mann K.G., Jenny R.J., and Krishnaswamy S. Cofactor proteins in the assembly and expression of blood clotting enzyme complexes. Annual Review of Biochemistry 57 (1988) 915-956
11. Mayer A.M.S., and Hamann M.T. Marine Pharmacology in 2000. Marine Biotechnology 6 (2004) 37-52
12. Rajapakse N., Jung W.K., Mendis E., Moon S.H., and Kim S.K. A novel anticoagulant derived from fish protein hydrolysate inhibits factor XIIa and platelet aggregation. Life Sciences 76 22 (2005) 2607-2619
13. Schmaier A. Contact activation: A revision. Thrombosis and Haemostasis 78 1 (1997) 101-107
14. Shi J., and Gilbert G.E. Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipids-binding sites. Blood 101 (2003) 2628-2636
15. Toda H., Yazawa M., Kondo K., Honma T., Narita K., and Yagi K. Amino acid sequence of calmodulin from scallop (Patinopecten) adductor muscle. Journal of Biochemistry (Tokyo) 90 5 (1981) 1493-1505