Combined determination of glucose and fructosamine in vitreous humor as a post-mortem tool to identify antemortem hyperglycemia

Review of Diabetic Studies

Volumn 5, Issue 4, 2008, Pages 220-224

  Vivero, Guillermo ^a   Vivero Salmerón, Guillermo ^a   Pérez Cárceles, Maria D ^b   Bedate, Andrés ^c   Luna, Aurelio ^b   Osuna, Eduardo ^b  

^a Hospital Virgen del Rosell   (Spain)

^b UNIVERSITY OF MURCIA   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Diabetes; Diagnosis; Fructosamine; Glucose; Post mortem; Vitreous humor

Indexed keywords

FRUCTOSAMINE; GLUCOSE; LACTIC ACID;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOPSY; CONTROLLED STUDY; DIABETES MELLITUS; DIAGNOSTIC VALUE; FEMALE; HUMAN; HYPERGLYCEMIA; MALE; RELIABILITY; ROC CURVE; SENSITIVITY AND SPECIFICITY; VITREOUS BODY;

EID: 67649243459     PISSN: 16136071     EISSN: 16140575     Source Type: Journal    
DOI: 10.1900/RDS.2008.5.220     Document Type: Article

References (21)

1. Fuller JH, Elford J, Goldblatt P, Adelstein AM. Diabetes mortality: new light on an underestimated public health problem. Diabetologia 1983. 24:336-341.
2. Goldacre MJ. Cause-specific mortality: understanding uncertain tips of the disease iceberg. J Epidemiol Community Health 1999. 47:491-496.
3. Goldacre MJ, Duncan ME, Cook Mozaffari P, Neil HA. Trends in mortality rates for death-certificate-coded diabetes mellitus in an English population 1979-1999. Diabet Med 2004. 21:936-939.
4. Khuu HM, Robinson CA, Brissie RM, Konrad RJ. Postmortem diagnosis of unsuspected diabetes mellitus established by determination of decedent's hemoglobin A1c level. J Forensic Sci 1999. 44:643-646. (Pubitemid 29230768)
5. Peclet C, Picotte P, Jobin F. The use of vitreous humor levels of glucose, lactic acid and blood levels of acetone to establish antemortem hyperglycemia in diabetics. Forensic Sci Int 1994. 65:1-6. (Pubitemid 24112954)
6. Sippel H, Mottönen M. Combined glucose and lactate values in vitreous humor for postmortem diagnosis of diabetes mellitus. Forensic Sci Int 1982. 19:217-222.
7. Banaschak S, Bajanowski T, Brinkmann B. Suicide of a diabetic by inducing hyperglycemic coma. Int J Legal Med 2000. 113:162-163. (Pubitemid 30339654)
8. Brinkmann B, Fechner G, Karger B, DuChesne A. Ketoacidosis and lactic acidosis-frequent cause of death in chronic alcoholics. Int J Legal Med 1998. 111:115-119. (Pubitemid 28197814)
9. Osuna E, García-Víllora A, Perez-Carceles MD, Conejero J, Abenza JM, Martinez P, Luna A. Vitreous humor fructosamine concentrations in the autopsy diagnosis of diabetes mellitus. Int J Legal Med 1999. 112:275-279. (Pubitemid 29409060)
10. Osuna E, García-Villora A, Perez-Carceles MD, Conejero J, Abenza JM, Martinez P, Luna A. Glucose and lactate in vitreous humor compared with the determination of fructosamine for the postmortem diagnosis of diabetes mellitus. Am J Forensic Med Pathol 2001. 22:244-249. (Pubitemid 32845455)
11. Tahara Y, Shima H. Kinetics of HbA1c glycated albumin, and fructosamine and analysis of their weight functions against preceding plasma glucose level. Diabetes Care 1995. 18(4):440-447.
12. John WG, Scott KW, Hawkroft DM. Glycated haemoglobin and glycated protein and glucose concentrations in necropsy blood samples. J Clin Pathol 1988. 41(4):415-418. (Pubitemid 18098416)
13. Valenzuela A. Postmortem diagnosis of diabetes mellitus. Quantitation of fructosamine and glycated haemoglobin. Forensic Sci Int 1988. 38:203-208. (Pubitemid 18245643)
14. Bunn HF, Gaffay KH, Gallop PM. The glycosylation of hemoglobin: relevance of diabetes mellitus. Science 1978. 200:21-27. (Pubitemid 8302924)
15. Winecker RE, Hammet-Stabler CA, Chapman JF, Ropero-Miller JD. HbA1c as a postmortem tool to identify glycemic control. J Forensic Sci 2002. 47:1373-1379. (Pubitemid 35314474)
16. Kennedy AL, Merimee TJ. Glycosylated serum protein and hemoglobin A1 levels to measure control of glycemia. Ann Intern Med 1981. 95:56-58. (Pubitemid 11079021)
17. Landis JR, Koch GG. An application of hierarchical kappa-type statistics in the assessment of majority agreement among multiple observers. Biometrics 1977. 33:363-374. (Pubitemid 8131514)
18. De Letter EA, Piette MH. Can routinely combined analysis of glucose and lactate in vitreous humor be useful in current forensic practice? Am J Forensic Med Pathol 1998. 19(4):335-342. (Pubitemid 29024541)
19. Sturner WQ, Sullivan A, Suzuki K. Lactic acid concentrations in vitreous humor: their use in asphyxial deaths in children. J Forensic Sci 1982. 28:222-230. (Pubitemid 13162248)
20. Schleyer F. Determination of the time of death in the early postmortem interval. In: Lundquist F. Methods of forensic science. Wiley Interscience Publishers, New York, 1963, vol.2, pp. 253-293.
21. Coe JI. Use of chemical determinations on vitreous humor in forensic pathology. J Forensic Sci 1972. 17:541-546.