Spatial Distribution of Ultrasound Targeted Microbubble Destruction Increases Cardiac Transgene Expression But Not Capillary Permeability

Ultrasound in Medicine and Biology

Volumn 35, Issue 7, 2009, Pages 1119-1126

  Geis, Nicolas A ^a   Mayer, Christian R ^a   Kroll, Richard D ^a   Hardt, Stefan E ^a   Katus, Hugo A ^a   Bekeredjian, Raffi ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Capillary permeability; Drug delivery; Echocardiography; Gene therapy; Heart; Microbubble; Ultrasound

Indexed keywords

CAPILLARY PERMEABILITY; GENE THERAPY; HEART; MICROBUBBLE; ULTRASOUND;

ACOUSTIC WAVES; CAPILLARITY; DRUG DELIVERY; ECHOCARDIOGRAPHY; GELATION; GENE EXPRESSION; GENETIC ENGINEERING; HARVESTING; NUCLEIC ACIDS; PROBES; RATS; SIZE DISTRIBUTION; ULTRASONIC TRANSMISSION;

ULTRASONICS;

DNA; EVANS BLUE; LUCIFERASE; PLASMID DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAPILLARY PERMEABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FEASIBILITY STUDY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSFECTION; MOLECULAR PROBE; NONHUMAN; PLASMID; PRIORITY JOURNAL; RAT; REPORTER GENE; TRANSGENE; TWO DIMENSIONAL ECHOCARDIOGRAPHY; ULTRASOUND TARGETED MICROBUBBLE DESTRUCTION;

ANIMALS; CAPILLARY PERMEABILITY; COLORING AGENTS; EVANS BLUE; GENE EXPRESSION REGULATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; HEART; MICROBUBBLES; MYOCARDIUM; RANDOM ALLOCATION; RATS; SONICATION; TRANSGENES;

EID: 67649220696     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2009.01.008     Document Type: Article

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