Fucose Is on the TRAIL of Colon Cancer

Gastroenterology

Volumn 137, Issue 1, 2009, Pages 36-39

  Haltiwanger, Robert S ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEATH RECEPTOR 4; DEATH RECEPTOR 5; ENZYME; FUCOSE; FUCOSYLTRANSFERASE; GLYCAN; GLYCAN DERIVATIVE; GUANOSINE DIPHOSPHATE FUCOSE; GUANOSINE DIPHOSPHATE MANNOSE; GUANOSINE DIPHOSPHATE MANNOSE 4 KETO 6 DEOXYMANNOSE 3,5 EPIMERASE 4 REDUCTASE; GUANOSINE DIPHOSPHATE MANNOSE 4,6 DEHYDRATASE; N ACETYLGLUCOSAMINE; O GLYCAN; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; CARBOHYDRATE METABOLISM; CARBOHYDRATE SYNTHESIS; CELL DEATH; CELL STRAIN HCT116; COLON CANCER; EDITORIAL; EXPERIMENTAL MOUSE; FUCOSYLATION; HUMAN; LIVER CELL CARCINOMA; MUTAGENESIS; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 67649217260     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.05.010     Document Type: Editorial

References (20)

1. Varki A., Cummings R.D., and Esko J.D. Essentials of glycobiology (2009), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
2. Becker D.J., and Lowe J.B. Fucose: biosynthesis and biological function in mammals. Glycobiology 13 (2003) 41R-53R
3. Luo Y., Koles K., Vorndam W., et al. Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats. J Biol Chem 281 (2006) 9393-9399
4. Luo Y., and Haltiwanger R.S. O-fucosylation of Notch occurs in the endoplasmic reticulum. J Biol Chem 280 (2005) 11289-11294
5. Smith P.L., Myers J.T., Rogers C.E., et al. Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus. J Cell Biol 158 (2002) 801-815
6. Shi S., and Stanley P. Protein O-fucosyltransferase I is an essential component of Notch signaling pathways. Proc Natl Acad Sci U S A 100 (2003) 5234-5239
7. Du J., Takeuchi H., Leonhard C.L., et al. O-Fucosylation of thrombospondin type 1 repeats is essential for normal gastrulation in mouse embryos. Glycobiology 17 (2007) 1243a
8. Stanley P. Regulation of Notch signaling by glycosylation. Curr Opin Struct Biol 17 (2007) 530-535
9. Wang X., Inoue S., Gu J., et al. Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice. Proc Natl Acad Sci U S A 102 (2005) 15791-15796
10. Wang X., Gu J., Ihara H., et al. Core fucosylation regulates epidermal growth factor receptor-mediated intracellular signaling. J Biol Chem 281 (2006) 2572-2577
11. Lee S.H., Takahashi M., Honke K., et al. Loss of core fucosylation of low-density lipoprotein receptor-related protein-1 impairs its function, leading to the upregulation of serum levels of insulin-like growth factor-binding protein 3 in Fut8-/- mice. J Biochem 139 (2006) 391-398
12. Zhao Y., Itoh S., Wang X., et al. Deletion of core fucosylation on alpha3beta1 integrin down-regulates its functions. J Biol Chem 281 (2006) 38343-38350
13. Moriwaki K., Noda K., Furukawa Y., et al. Deficiency of GMD leads to escape from NK cell-mediated tumor surveillance through modulators of TRAIL signaling. Gastroenterology 137 (2009) 188-198
14. Falschlehner C., Emmerich C.H., Gerlach B., et al. TRAIL signalling: decisions between life and death. Int J Biochem Cell Biol 39 (2007) 1462-1475
15. Ashkenazi A., and Herbst R.S. To kill a tumor cell: the potential of proapoptotic receptor agonists. J Clin Invest 118 (2008) 1979-1990
16. Matsumura K., Higashida K., Ishida H., et al. Carbohydrate binding specificity of a fucose-specific lectin from Aspergillus oryzae: a novel probe for core fucose. J Biol Chem 282 (2007) 15700-15708
17. Wang C., Qi R., Li N., et al. Notch1 signaling sensitizes TRAIL-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression. J Biol Chem (2009) Apr 17 [Epub ahead of print]
18. Wagner K.W., Punnoose E.A., Januario T., et al. Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Nat Med 13 (2007) 1070-1077
19. Yoshida T., Shiraishi T., Horinaka M., et al. Glycosylation modulates TRAIL-R1/death receptor 4 protein: different regulations of two pro-apoptotic receptors for TRAIL by tunicamycin. Oncol Rep 18 (2007) 1239-1242
20. Ripka J., Adamany A., and Stanley P. Two Chinese hamster ovary glycosylation mutants affected in the conversion of GDP-mannose to GDP-fucose. Arch Biochem Biophys 249 (1986) 533-545