A highly reproducible continuous process for hydroxyapatite nanoparticles synthesis

Journal of Nanoscience and Nanotechnology

Volumn 9, Issue 6, 2009, Pages 3387-3395

  Gomes, Paulo J ^a,b   Silva, Viviana M T M ^a   Quadros, Paulo A ^a   Dias, Madalena M ^b   Lopes, Jose C B ^a,b  

^a Fluidlnova Engenharia de Fluidos SA   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Hydroxyapatite; Micromixing; Nanoparticles; NanoXIM; NETmix

Indexed keywords

ALKALINE SOLUTIONS; BIOCEMENTS; BONE GRAFT; BONE REPLACEMENT; CALCIUM PHOSPHATE NANOPARTICLES; CONTINUOUS PROCESS; CRYSTALLINITY; DISTRIBUTION SCHEME; METALLIC IMPLANTS; MICROMIXING; MILLING PROCESS; MOLAR RATIO; NANOMETRIC STRUCTURE; NANOPARTICLES SYNTHESIS; NANOXIM; NETWORK REACTORS; NUTRITIONAL SUPPLEMENTS; SUPERSATURATION DEGREE; TISSUE FORMATION;

APATITE; BIOLOGICAL MATERIALS; BONE; CALCIUM; CALCIUM ALLOYS; CALCIUM PHOSPHATE; GRAFTS; HYDROXYAPATITE; MILLING (MACHINING); NANOPARTICLES; PHOSPHORUS; SINTERING;

BIOMATERIALS;

EID: 67649216932     PISSN: 15334880     EISSN: None     Source Type: Journal    
DOI: 10.1166/jnn.2009.NS06     Document Type: Conference Paper

References (32)

1. W. Paul and C. P. Sharma, J. Mater. Sci.-Mater. Med. 10, 383 (1999).
2. B. Palazzo, M. Iafisco, M. Laforgia, N. Margiotta, G. Natile, C. L. Bianchi, D. Walsh, S. Mann, and N. Roveri, Adv. Fund. Mater. 17, 2180 (2007).
3. W. Paul, J. Nesamony, and C. P. Sharma, J. Biomed. Mater. Res. 61, 660 (2002).
4. P. N. Kumta, C. Sfeir, D. Lee, D. Olton, and D. Choi, Acta Bioma-terialia 1, 65 (2005).
5. M. B. Nair, S. S. Babu, H. K. Varma, and A. John, Acta Biomateri-alia 4, 173 (2008).
6. Y. Z. Wan, Y. Huang, C. D. Yuan, S. Raman, Y. Zhu, H. J. Jiang, F. He, and C. Gao, Mater. Sci. Eng., C 27, 855 (2007).
7. C. Balcik, T. Tokdemir, A. Senkoylu, N. Koc, M. Timucin, S. Akin, P. Korkusuz, and F. Korkusuz, Acta Biomaterialia 3, 985 (2007).
8. O. S. Schindler, S. R. Cannon, T. W. R. Briggs, and G. W. Blunn, The Knee 14, 458 (2007).
9. M. B. Conz, J. M. Granjeiro, and G. de Almeida Soares, J. Appl. Oral Sci. 13, 136 (2005).
10. L. C. Chow and S. Takagi, J. Res. Natl. Inst. Stand. Technol. 106, 1029 (2001).
11. C. E. Wen, W. Xu, W. Y. Hu, and P. D. Hodgson, Acta Biomaterialia 3, 403 (2007).
12. A. Bishop, Cs. Balazsi, and P. Gouma, Proceeding of the 8th Polymers for Advanced Technologies International Symposium, Budapest, Hungary, September (2005).
13. K. Ozeki, H. Aoki, and Y. Fukui, Journal of Materials Science 40, 2837 (2005).
14. R. Z. Le Geros, Calcium Phosphates in Oral Biology and Medicine, edited by H. M. Myers, Karger, Basel (1991), Chap. 6, pp. 110-118.
15. L. C. Chow, L. Sun, and B. Hockey, J. Res. Natl. Inst. Stand. Technol. 109, 543 (2004).
16. M. Sinha, S. B. Qadri, and C. P. Singh, 10th Foresight Conference on Molecular Nanotechnology, Maryland, USA (2002).
17. J. Gómez-Morales, J. Torrent-Burguós, T. Boix, J. Fraile, and R. Rodrfguez-Clemente, Cryst. Res. Technol. 36, 15 (2001).
18. D. Yang, Z. Yang, X. Li, L.-Z. Di, and H. Zhao, Ceram. Int. 31, 1021 (2005).
19. C. Liu, Y. Huang, W. Shen, and J. Cui, Biomaterials 22, 301 (2001).
20. J. F. Conn and L. A. Jessen, Patent US4324772 (1982).
21. V. N. Rudin, V. F. Komarov, I. V. Melikhov, V. V. Minaev, A. Y. Orlov, and V. E. Bozhevoinov, Patent WO0202461 (2002).
22. J. Y. Ying, E. S. Ahn, and A. Nakahira, Patent US6013591 (2000).
23. E. S. Ahn, Patent US2005031704 (2005).
24. M. Ramakingam and S. Ramakrishna, Patent US2005226939 (2005).
25. J. Ren and X. Zhou, Patent CN1587195 (2005).
26. P. Luo, Patent US5858318 (1999).
27. Y. E. Greish and P. W. Brown, Journal of Biomedical Materials Research-Part B: Applied Biomaterials 67B, 632 (2003).
28. R. Kumar, K. H. Prakash, P. Cheang, and K. A. Khor, Langnmir 20, 5196 (2004).
29. J. Gómez-Morales, J. Torrent-Burguesand R. Rodrfguez-Clemente, Cryst. Res. Technol. 36, 1065 (2001).
30. J. C. B. Lopes, P. E. M. S. C. Laranjeira, M. M. Q. Dias, and A. A. A. Martins, Patent WO 2005/077508 (2005).
31. J. C. B. Lopes, M. M. Q. Dias, V. M. T. M. Silva, P. A. Q. O. Santos, F. J. M. Monteiro, P. J. C. Gomes, and A. Y. P. Mateus, PT Patent 103528 (pending) (2006).
32. A. L. Patterson, Phys. Rev. 56, 978 (1939).