Structure of the inhibitor W7 bound to the regulatory domain of cardiac troponin C

Biochemistry

Volumn 48, Issue 24, 2009, Pages 5541-5552

  Hoffman, Ryan M B ^a   Sykes, Brian D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BLOCKING MECHANISMS; BOUND STATE; CARDIAC TROPONIN C; CONFORMATIONAL CHANGE; MULTIPLE DATA; REGULATORY DOMAIN; STERIC INTERACTIONS; STRIATED MUSCLES; STRUCTURE ACTIVITY RELATIONSHIPS; STRUCTURE DETERMINATION; TARGET FUNCTIONS; TROPONIN C; TROPONIN I;

CALCIUM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

MUSCLE;

LEVOSIMENDAN; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; TRIFLUOPERAZINE; TROPONIN C;

ARTICLE; CALCIUM BINDING; CARBON NUCLEAR MAGNETIC RESONANCE; CONFORMATIONAL TRANSITION; ELECTRICITY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTON NUCLEAR MAGNETIC RESONANCE; SKELETAL MUSCLE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TROPONIN C;

EID: 67649214132     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9001826     Document Type: Article

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