Hair Cell Bundles: Flexoelectric Motors of the Inner Ear

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  Breneman, Kathryn D ^a   Brownell, William E ^b   Rabbitt, Richard D ^a,c  

^a Department of Electrical and Computer Engineering   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c MARINE BIOLOGICAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CYTOLOGY; HAIR CELL; INNER EAR; PHYSIOLOGY;

ANIMALS; EAR, INNER; HAIR CELLS, AUDITORY; MODELS, BIOLOGICAL;

EID: 67649185860     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005201     Document Type: Article

References (58)

1. Mulroy MJ, Williams RS, (1987) Auditory stereocilia in the alligator lizard. Hear Res 25: 11-21.
2. Garfinkle TJ, Saunders JC, (1983) Morphology of inner hair cell stereocilia in C57BL/6J mice as studied by scanning electron microscopy. Otolaryngol Head Neck Surg 91: 421-426.
3. Hackney CM, Fettiplace R, Furness DN, Department of CNeuroscience KUSUK(1993) The functional morphology of stereociliary bundles on turtle cochlear hair cells. Hearing research 69(1-2): 163-175.
4. Petrov AG, (1975) Flexoelectric model for active transport New York Plenum Press pp. 111-125.
5. Petrov AG, (2002) Flexoelectricity of model and living membranes. Biochim Biophys Acta 1561: 1-25.
6. Petrov AG, Usherwood PN, (1994) Mechanosensitivity of cell membranes. Ion channels, lipid matrix and cytoskeleton. Eur Biophys J 23: 1-19.
7. Hudspeth AJ, (1982) Extracellular current flow and the site of transduction by vertebrate hair cells. The Journal of neuroscience: the official journal of the Society for Neuroscience 2(1): 1-10.
8. Anvari B, Zhang R, Qian F, Rajagopalan L, Pereira FA, et al.(2007) Effects of prestin on membrane mechanics and electromechanics. Conf Proc IEEE Eng Med Biol Soc 1: 5384-5386.
9. Hudspeth AJ, (2008) Making an effort to listen: mechanical amplification in the ear. Neuron 59: 530-545.
10. Eguíluz VM, Ospeck M, Choe Y, Hudspeth AJ, Magnasco MO, (2000) Essential nonlinearities in hearing. Phys Rev Lett 84: 5232-5235.
11. Huxley AF, (1974) Muscular contraction. J Physiol 243: 1-43.
12. Holton T, Hudspeth AJ, (1983) A micromechanical contribution to cochlear tuning and tonotopic organization. Science 222(4623): 508-510.
13. Frishkopf LS, DeRosier DJ, (1983) Mechanical tuning of free-standing stereociliary bundles and frequency analysis in the alligator lizard cochlea. Hear Res 12: 393-404.
14. Holt JR, Gillespie SK, Provance DW, Shah K, Shokat KM, et al.(2002) A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells. Cell 108: 371-381.
15. Dallos P, Wu X, Cheatham MA, Gao J, Zheng J, et al.(2008) Prestin-based outer hair cell motility is necessary for mammalian cochlear amplification. Neuron 58: 333-339.
16. Stepanyan R, Belyantseva IA, Griffith AJ, Friedman TB, Frolenkov GI, (2006) Auditory mechanotransduction in the absence of functional myosin-XVa. J Physiol 576: 801-808.
17. Verpy E, Weil D, Leibovici M, Goodyear RJ, Hamard G, et al.(2008) Stereocilin-deficient mice reveal the origin of cochlear waveform distortions. Nature 456: 255-258.
18. Harasztosi C, Gummer AW, (2009) Locating MET Channels in Outer Hair Cells Near the Lower End of the Tip Link Baltimore, MD Association for Research in Otolaryngology.
19. Liberman MC, (1980) Efferent synapses in the inner hair cell area of the cat cochlea: an electron microscopic study of serial sections. Hear Res 3: 189-204.
20. Guinan JJ, Stankovic KM, (1997) Medial efferent inhibition produces the largest equivalent attenuations at moderate to high sound levels in cat auditory-nerve fibers. J Acoust Soc Am 100: 1980-1990.
21. Geisler C, (1974) Model of crossed olivocochlear bundle effects. J Acoust Soc Am 56: 1910-1912.
22. Fuchs P, Murrow B, (1992) Cholinergic inhibition of short (outer) hair cells of the chick's cochlea. J Neurosci 12: 800-809.
23. Flock A, Russell I, (1976) Inhibition by efferent nerve fibres: action on hair cells and afferent synaptic transmission in the lateral line canal organ of the burbot Lota lota. J Physiol 257: 45-62.
24. Benser ME, Marquis RE, Hudspeth AJ, Howard Hughes Medical Institute RUNYNYUSA(1996) Rapid, active hair bundle movements in hair cells from the bullfrog's sacculus. The Journal of neuroscience: the official journal of the Society for Neuroscience 16(18): 5629-5643.
25. Martin P, Hudspeth AJ, Howard Hughes Medical Institute LoSNTRUYANYNYUSA(1999) Active hair-bundle movements can amplify a hair cell's response to oscillatory mechanical stimuli. Proceedings of the National Academy of Sciences of the United States of America 96(25): 14306-14311.
26. Kennedy HJ, Evans MG, Crawford AC, Fettiplace R, (2003) Fast adaptation of mechanoelectrical transducer channels in mammalian cochlear hair cells. Nat Neurosci 6: 832-836.
27. Ricci AJ, Crawford AC, Fettiplace R, (2000) Active hair bundle motion linked to fast transducer adaptation in auditory hair cells. J Neurosci 20: 7131-7142.
28. Murugasu E, Russell IJ, (1996) The effect of efferent stimulation on basilar membrane displacement in the basal turn of the guinea pig cochlea. J Neurosci 16(1): 325-332.
29. Lin HW, Schneider ME, Kachar B, (2005) When size matters: the dynamic regulation of stereocilia lengths. Curr Opin Cell Biol 17: 55-61.
30. Hudspeth AJ, (2005) How the ear's works work: mechanoelectrical transduction and amplification by hair cells. C R Biol 328: 155-162.
31. Glassinger E, Lee AC, Raphael RM, (2005) Electromechanical effects on tether formation from lipid membranes: a theoretical analysis. Phys Rev E Stat Nonlin Soft Matter Phys 72: 041926.
32. Nam JH, Cotton JR, Peterson EH, Grant W, (2006) Mechanical properties and consequences of stereocilia and extracellular links in vestibular hair bundles. Biophys J 90: 2786-2795.
33. Hochmuth RM, Evans EA, (1982) Extensional flow of erythrocyte membrane from cell body to elastic tether. I. Analysis. Biophys J 39: 71-81.
34. Hochmuth RM, Wiles HC, Evans EA, McCown JT, (1982) Extensional flow of erythrocyte membrane from cell body to elastic tether. II. Experiment. Biophys J 39: 83-89.
35. Tiersten H, (1969) Linear piezoelectric plate vibrations; elements of the linear theory of piezoelectricity and the vibrations of piezoelectric plates New York Plenum Press.
36. Breneman KD, Brownell WE, Rabbitt RD, (submitted 08/2008) Stereocilia: Flexoelectric Motors of The Inner Ear. Science.
37. Weiss T, (1996) Cellular Biophysics. Vol. 2: Electrical Properties Cambridge MIT Press.
38. Meirovitch L, (1967) Analytical Methods in Vibrations New York McMillian.
39. Rabbitt RD, Clifford S, Breneman KD, Farrell BF, Brownell W, (2008) Power Efficiency of Outer Hair Cell Somatic Electromotility. submitted PLCB.
40. Zetes DE, Steele CR, (1997) Fluid-structure interaction of the stereocilia bundle in relation to mechanotransduction. J Acoust Soc Am 101: 3593-3601.
41. ten Kate JH, Kuiper JW, (1970) The Viscosity of Pike's Endolymph. J Exp Biol 53: 495-500.
42. Fung YC, (1979) A First Course in Continuum Mechanics Englewood Cliffs, New Jersey Prentice-Hall, Inc.
43. Raphael RM, Popel AS, Brownell WE, (2000) A membrane bending model of outer hair cell electromotility. Biophys J 40(4): 2844-2862.
44. Muller M, von Hunerbein K, Hoidis S, Smolders JW, (2005) A physiological place-frequency map of the cochlea in the CBA/J mouse. Hear Res 202: 63-73.
45. Wright A, (1984) Dimensions of the cochlear stereocilia in man and guinea pig. Hear Res 13(1): 89-98.
46. Vater M, Kossl M, (1996) Further studies on the mechanics of the cochlear partition in the mustached bat. I. Ultrastructural observations on the tectorial membrane and its attachments. Hear Res 94: 63-77.
47. Tilney LG, Egelman EH, DeRosier DJ, Saunder JC, (1983) Actin filaments, stereocilia, and hair cells of the bird cochlea. II. Packing of actin filaments in the stereocilia and in the cuticular plate and what happens to the organization when the stereocilia are bent. J Cell Biol 96: 822-834.
48. Weiss TF, Mulroy MJ, Turner RG, Pike CL, (1976) Tuning of single fibers in the cochlear nerve of the alligator lizard: relation to receptor morphology. Brain Res 115: 71-90.
49. Hackney CM, Fettiplace R, Furness DN, (1993) The functional morphology of stereociliary bundles on turtle cochlear hair cells. Hear Res 69: 163-175.
50. Happel J, Brenner H, (1983) Low Reynolds Number Hydrodynamics with special applications to particulate media. pp. 572.
51. Breneman KD, Highstein SM, Boyle RD, Rabbitt RD, (2008) The Passive Cable Properties of Hair Cell Stereocilia and Their Contribution to Somatic Capacitance Measurements. Biophys J.
52. Hudspeth AJ, (1985) The cellular basis of hearing: the biophysics of hair cells. Science 230(4727): 745-752.
53. Rattay F, Gebeshuber IC, Gitter AH, (1998) The mammalian auditory hair cell: a simple electric circuit model. J Acoust Soc Am 103: 1558-1565.
54. Cotton J, Grant W, (2004) Computational models of hair cell bundle mechanics: II. Simplified bundle models. Hear Res 197: 105-111.
55. Cotton JR, Grant JW, (2000) A finite element method for mechanical response of hiar cell ciliary bundles. J Biomech Eng 144: 44-50.
56. Halter JA, Kruger RP, Yium MJ, Brownell WE, (1997) The influence of the subsurface cisterna on the electrical properties of the outer hair cell. Neuroreport 8: 2517-2521.
57. Nam JH, Cotton JR, Grant W, (2007) A virtual hair cell, I: addition of gating spring theory into a 3-D bundle mechanical model. Biophys J 92: 1918-1928.
58. Freeman DM, Abnet CC, (2000) Deformations of the isolated mouse tectorial membrane produced by oscillatory forces. Hear Res 144: 29-46.