ORAOV1-A correlates with poor differentiation in oral cancer

Journal of Dental Research

Volumn 88, Issue 5, 2009, Pages 433-438

  Jiang, L ^a   Yang, H S ^b   Wang, Z ^a   Zhou, Y ^a   Zhou, M ^a   Zeng, X ^a   Chen, Q M ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Differentiation; Oral squamous cell carcinoma; ORAOV1; ORAOV1 A; Splice variant

Indexed keywords

ISOPROTEIN; MESSENGER RNA; ORAOV1 PROTEIN, HUMAN; TUMOR PROTEIN;

ARTICLE; BASE PAIRING; CANCER STAGING; CELL TRANSFORMATION; EXON; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LYMPH NODE METASTASIS; MALE; MIDDLE AGED; MOLECULAR GENETICS; MOUTH MUCOSA; MOUTH TUMOR; OPEN READING FRAME; PATHOLOGY; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; STOP CODON; TUMOR CELL LINE;

BASE PAIRING; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CODON, TERMINATOR; EXONS; FEMALE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MOUTH MUCOSA; MOUTH NEOPLASMS; NEOPLASM PROTEINS; NEOPLASM STAGING; OPEN READING FRAMES; PROGNOSIS; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 67649158221     PISSN: 00220345     EISSN: None     Source Type: Journal    
DOI: 10.1177/0022034509336994     Document Type: Article

References (21)

1. Black DL (2003). Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem 72:291-336. (Pubitemid 36930448)
2. Chang JT, Wang HM, Chang KW, Chen WH, Wen MC, Hsu YM, et al. (2005). Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC): overexpression of NPM, CDK1 and NDRG1 and underexpression of CHES1. Int J Cancer 114:942-949. (Pubitemid 40504475)
3. Choi S, Myers JN (2008). Molecular pathogenesis of oral squamous cell carcinoma: implications for therapy. J Dent Res 87:14-32.
4. Engels K, Knauer SK, Metzler D, Simf C, Struschka O, Bier C, et al. (2007). Dynamic intracellular survivin in oral squamous cell carcinoma: underlying molecular mechanism and potential as an early prognostic marker. J Pathol 211:532-540. (Pubitemid 46502429)
5. Etoh T, Kanai Y, Ushijima S, Nakagawa T, Nakanishi Y, Sasako M, et al. (2004). Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. Am J Pathol 164:689-699. (Pubitemid 38364682)
6. Faustino NA, Cooper TA (2003). Pre-mRNA splicing and human disease. Genes Dev 17:419-437.
7. Garcia-Blanco MA, Baraniak AP, Lasda EL (2004). Alternative splicing in disease and therapy. Nat Biotechnol 22:535-546.
8. Holmila R, Fouquet C, Cadranel J, Zalcman G, Soussi T (2003). Splice mutations in the p53 gene: case report and review of the literature. Hum Mutat 21:101-102.
9. Honda K, Yamada T, Seike M, Hayashida Y, Idogawa M, Kondo T, et al. (2004). Alternative splice variant of actinin-4 in small cell lung cancer. Oncogene 23:5257-5262. (Pubitemid 38980358)
10. Huang X, Gollin SM, Raja S, Godfrey TE (2002). High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells. Proc Natl Acad Sci USA 99:11369-11374. (Pubitemid 34920932)
11. Jiang L, Zeng X, Yang H, Wang Z, Shen J, Bai JP, et al. (2008). Oral cancer overexpressed 1 (ORAOV1): a regulator for the cell growth and tumor angiogenesis in oral squamous cell carcinoma. Int J Cancer 123:1779-1786.
12. Lewin F, Norell SE, Johansson H, Gustavsson P, Wennerberg J, Biorklund A, et al. (1998). Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck. Cancer 82:1367-1375.
13. Maniatis T, Tasic B (2002). Alternative pre-mRNA splicing and proteome expansion in metazoans. Nature 418:236-243. (Pubitemid 34773783)
14. Massiello A, Salas A, Pinkerman RL, Roddy P, Roesser JR, Chalfant CE (2004). Identification of two RNA cis-elements that function to regulate the 5′ splice site selection of Bcl-x pre-mRNA in response to ceramide. J Biol Chem 279:15799-15804. (Pubitemid 38509266)
15. Miller CS, Johnstone BM (2001). Human papillomavirus as a risk factor for oral squamous cell carcinoma: a meta-analysis, 1982-1997. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 91:622-635. (Pubitemid 33601674)
16. Neville BW, Day TA (2002). Oral cancer and precancerous lesions. CA Cancer J Clin 52:195-215.
17. Pagani F, Baralle FE (2004). Genomic variants in exons and introns: identifying the splicing spoilers. Nat Rev Genet 5:389-396. (Pubitemid 38529410)
18. Scully C (2002). Oral squamous cell carcinoma: from a hypothesis about a virus to concern about possible sexual transmission. Oral Oncol 38:227-234.
19. Venables JP (2004). Aberrant and alternative splicing in cancer. Cancer Res 64:7647-7654.
20. Wang Z, Jiang L, Huang C, Li Z, Chen L, Gou L, et al. (2008). Comparative proteomic approach to screening of potential diagnostic and therapeutic targets for oral squamous cell carcinoma. Mol Cell Proteomics 7:1639-1650.
21. Xia J, Chen QM, Li BQ, Zeng X (2007). Amplifications of TAOS1 and EMS1 genes in oral carcinogenesis: association with clinicopathological features. Oral Oncol 43:508-514. (Pubitemid 46561436)