Association of the progesterone receptor gene with endometrial cancer risk in a Chinese population

Cancer

Volumn 115, Issue 12, 2009, Pages 2693-2700

  Xu, Wang Hong ^a,b   Long, Ji Rong ^c   Zheng, Wei ^c   Ruan, Zhi Xian ^a   Cai, Qiuyin ^c   Cheng, Jia Rong ^a   Xiang, Yong Bing ^a   Shu, Xiao Ou ^c,d  

^a SHANGHAI CANCER INSTITUTE   (China)

^b FUDAN UNIVERSITY   (China)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endometrial cancer; Genotype; Haplotype; Progesterone receptor gene; Single nucleotide polymorphism

Indexed keywords

CYTOSINE; DNA; GUANINE; PROGESTERONE RECEPTOR; THYMINE;

ADULT; AGED; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CHINESE; CONTROLLED STUDY; ENDOMETRIUM CANCER; FEMALE; GENETIC IDENTIFICATION; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; POPULATION RESEARCH; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ASIAN CONTINENTAL ANCESTRY GROUP; ENDOMETRIAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, PROGESTERONE; RISK FACTORS;

EID: 67649158198     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.24289     Document Type: Article

References (23)

1. Siiteri PK. Steroid hormones and endometrial cancer. Cancer Res. 1978;38:4360-4366. (Pubitemid 9054232)
2. Key TJ, Pike MC. The dose-effect relationship between 'unopposed' oestrogens and endometrial mitotic rate: its central role in explaining and predicting endometrial cancer risk. Br J Cancer. 1988;57:205-212.
3. Gielen SC, Hanekamp EE, Hanifi-Moghaddam P, et al. Growth regulation and transcriptional activities of estrogen and progesterone in human endometrial cancer cells. Int J Gynecol Cancer. 2006;16:110-120.
4. Smid-Koopman E, Kuhne LC, Hanekamp EE, et al. Progesterone-induced inhibition of growth and differential regulation of gene expression in PRA- and/or PRB-expressing endometrial cancer cell lines. J Soc Gynecol Investig. 2005;12:285-292. (Pubitemid 40615100)
5. Kastner P, Krust A, Turcotte B, et al. Two distinct estrogen-regulated promoters generate transcripts encoding the 2 functionally different human progesterone receptor forms A and B. EMBO J. 1990;9:1603-1614. (Pubitemid 20137018)
6. Vegeto E, Allan GF, Schrader WT, Tsai MJ, McDonnell DP, O'Malley BW. The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. Cell. 1992;69:703-713.
7. De Vivo I, Huggins GS, Hankinson SE, et al. A functional polymorphism in the promoter of the progesterone receptor gene associated with endometrial cancer risk. Proc Natl Acad Sci U S A. 2002;99:12263-12268.
8. Junqueira MG, da Silva ID, Nogueira-de-Souza NC, et al. Progesterone receptor (PROGINS) polymorphism and the risk of endometrial cancer development. Int J Gynecol Cancer. 2007;17:229-232.
9. Sartorius CA, Melville MY, Hovland AR, Tung L, Takimoto GS, Horwitz KB. A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform. Mol Endocrinol. 1994;8:1347-1360. (Pubitemid 24335078)
10. Dossus L, Canzian F, Kaaks R, Boumertit A, Weiderpass E. No association between progesterone receptor gene +331G/A polymorphism and endometrial cancer. Cancer Epidemiol Biomarkers Prev. 2006;15:1415-1416. (Pubitemid 44125304)
11. Couzin J. Genomics. The HapMap gold rush: researchers mine a rich deposit [serial online]. Science. 2006;312:1131. (Pubitemid 43801114)
12. Xu WH, Shrubsole MJ, Xiang YB, et al. Dietary folate intake, MTHFR genetic polymorphisms and the risk of endometrial cancer among Chinese women. Cancer Epidemiol Biomarkers Prev. 2007;16:281-287.
13. Cheng JR, Guan SF, Wang XL, Han LH, Gao YT. Feasibility of genetic polymorphisms analysis using genomic DNA obtained from human buccal cells. Ai Zheng. 2005;24:893-897.
14. Laine ML, Farre MA, Crusius JB, van Winkelhoff AJ, Pena AS. The mouthwash: a non-invasive sampling method to study cytokine gene polymorphisms. J Periodontol. 2000;71:1315-1318.
15. de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, Altshuler D. Efficiency and power in genetic association studies. Nat Genet. 2005;37:1217-1223.
16. Hardenbol P, Yu F, Belmont J, et al. Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay. Genome Res. 2005;15:269-275. (Pubitemid 40309391)
17. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263-265. (Pubitemid 40202029)
18. Gabriel SB, Schaffner SF, Nguyen H, et al. The structure of haplotype blocks in the human genome. Science. 2002;296:2225-2229. (Pubitemid 34680308)
19. Lin DY, Zeng D, Millikan R. Maximum likelihood estimation of haplotype effects and haplotype-environment interactions in association studies. Genet Epidemiol. 2005;29:299-312. (Pubitemid 41720949)
20. Kumar NS, Richer J, Owen G, Litman E, Horwitz KB, Leslie KK. Selective down-regulation of progesterone receptor isoform B in poorly differentiated human endometrial cancer cells: implications for unopposed estrogen action. Cancer Res. 1998;58:1860-1865. (Pubitemid 28217459)
21. Lattuada D, Somigliana E, Vigano P, Candiani M, Pardi G, Di Blasio AM. Genetics of endometriosis: a role for the progesterone receptor gene polymorphism PROGINS? Clin Endocrinol (Oxf). 2004;61:190-194.
22. Wieser F, Schneeberger C, Tong D, Tempfer C, Huber JC, Wenzl R. PROGINS receptor gene polymorphism is associated with endometriosis. Fertil Steril. 2002;77:309-312. (Pubitemid 34083553)
23. De Carvalho CV, Nogueira-De-Souza NC, Costa AM, et al. Genetic polymorphisms of cytochrome P450cl7alpha (CYP17) and progesterone receptor genes (PROGINS) in the assessment of endometriosis risk. Gynecol Endocrinol. 2007;23:29-33. (Pubitemid 46269306)