Gene expression profiling in rat liver treated with compounds inducing elevation of bilirubin

Human and Experimental Toxicology

Volumn 28, Issue 4, 2009, Pages 231-244

  Hirode, M ^a,b   Horinouchi, A ^a,b   Uehara, T ^b   Ono, A ^b,c   Miyagishima, T ^b   Yamada, H ^b   Nagao, T ^d   Ohno, Y ^b,c   Urushidani, T ^b,e  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d Food Safety Commission of Japan   (Japan)

^e DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

Author keywords

Bilirubin; Liver; Principal component analysis; Rat; Toxicogenomics

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; ACETYLSALICYLIC ACID; ALLYL ALCOHOL; BENDAZAC; BILIRUBIN; BIOLOGICAL MARKER; CHLORPROMAZINE; COLCHICINE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; ETHINYLESTRADIOL; GEMFIBROZIL; GLIBENCLAMIDE; INDOMETACIN; IPRONIAZID; ISONIAZID; METHAPYRILENE; METHOTREXATE; METHYLTESTOSTERONE; NITROFURANTOIN; PENICILLAMINE; PHALLOIDIN; RIFAMPICIN; TETRACYCLINE; THIOACETAMIDE; TICLOPIDINE; TRANSCRIPTOME; VALPROIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; GENE; GENE CLUSTER; GENE EXPRESSION PROFILING; HYPERBILIRUBINEMIA; LIVER; MALE; MOLECULAR PROBE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PREDICTOR VARIABLE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; RAT; REPEATED DRUG DOSE; SINGLE DRUG DOSE; UNINDEXED SEQUENCE;

ANIMALS; BILIRUBIN; BLOOD CHEMICAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; GENE EXPRESSION PROFILING; GLUCURONIC ACID; LIVER; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHARMACEUTICAL PREPARATIONS; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

RATTUS;

EID: 67649154479     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1177/0960327109104528     Document Type: Article

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