Nesiritide, heart failure, and renal dysfunction: Irrational exuberance or throwing the baby out with the bathwater : Eo: Impact of "nesiritide on renal function and mortality in patients suffering from heart failure by Dontas" et al.

Cardiovascular Drugs and Therapy

Volumn 23, Issue 3, 2009, Pages 183-186

  Witteles, Ronald M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERYL TRINITRATE; NESIRITIDE; PLACEBO;

ACUTE HEART FAILURE; BOLUS INJECTION; CLINICAL TRIAL; DIURESIS; DRUG EFFECT; DRUG HALF LIFE; EDITORIAL; HEART FAILURE; HUMAN; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; MORTALITY; NATRIURESIS; PRIORITY JOURNAL;

HEART FAILURE; HUMANS; KIDNEY; KIDNEY FAILURE; NATRIURETIC AGENTS; NATRIURETIC PEPTIDE, BRAIN;

EID: 67649097095     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10557-009-6169-4     Document Type: Editorial

References (20)

1. Dontas I, Xanthos T, Dontas I, Lelovas P, Papadimitriou L. Impact of nesiritide on renal function and mortality in patients suffering from heart failure. Cardiovasc Drugs Ther. 2009;23: This issue.
2. NC Davidson AD Struthers 1994 Brain natriuretic peptide J Hypertens 12 329 36
3. SJ Holmes EA Espiner AM Richards TG Yandle C Frampton 1993 Renal, endocrine, and hemodynamic effects of human brain natriuretic peptide in normal man J Clin Endocrinol Metab 76 91 6
4. LS Marcus D Hart M Packer 1996 Hemodynamic and renal excretory effects of human brain natriuretic peptide infusion in patients with congestive heart failure. A double-blind, placebo-controlled, randomized crossover trial Circulation 94 3184 9
5. RM Mills TH LeJemtel DP Horton 1999 Sustained hemodynamic effects of an infusion of nesiritide (human b-type natriuretic peptide) in heart failure: a randomized, double-blind, placebo-controlled clinical trial. Natrecor Study Group J Am Coll Cardiol 34 155 62
6. TA Scriven JC Burnett Jr 1985 Effects of synthetic atrial natriuretic peptide on renal function and renin release in acute experimental heart failure Circulation 72 892 7
7. Natrecor (nesiritide) for Injection: Package Insert. (Accessed February 8, 2009, at http://www.fda.gov/cder/foi/label/2006/020920s012lbl.pdf.)
8. Publication Committee for the VMAC Investigators (Vasodilatation in the Management of Acute CHF) 2002 Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial JAMA 287 1531 40
9. EJ Topol 2005 Nesiritide-not verified N Engl J Med 353 113 6
10. PJ Hauptman MA Schnitzler J Swindle TE Burroughs 2006 Use of nesiritide before and after publications suggesting drug-related risks in patients with acute decompensated heart failure JAMA 296 1877 84
11. CW Yancy MT Saltzberg RL Berkowitz 2004 Safety and feasibility of using serial infusions of nesiritide for heart failure in an outpatient setting (from the FUSION I trial) Am J Cardiol 94 595 601 (Pubitemid 39165837)
12. Gellene D. For Scios CEO, sale is close to the heart. Los Angeles Times February 11, 2003:C-1.
13. DJ Wang TC Dowling D Meadows 2004 Nesiritide does not improve renal function in patients with chronic heart failure and worsening serum creatinine Circulation 110 1620 5
14. JD Sackner-Bernstein M Kowalski M Fox K Aaronson 2005 Short-term risk of death after treatment with nesiritide for decompensated heart failure: a pooled analysis of randomized controlled trials JAMA 293 1900 5
15. JD Sackner-Bernstein HA Skopicki KD Aaronson 2005 Risk of worsening renal function with nesiritide in patients with acutely decompensated heart failure Circulation 111 1487 91
16. WT Abraham KF Adams GC Fonarow 2005 In-hospital mortality in patients with acute decompensated heart failure requiring intravenous vasoactive medications: an analysis from the Acute Decompensated Heart Failure National Registry (ADHERE) J Am Coll Cardiol 46 57 64 (Pubitemid 40905130)
17. RR Arora PK Venkatesh J Molnar 2006 Short and long-term mortality with nesiritide Am Heart J 152 1084 90
18. RM Witteles D Kao D Christopherson 2007 Impact of nesiritide on renal function in patients with acute decompensated heart failure and pre-existing renal dysfunction a randomized, double-blind, placebo-controlled clinical trial J Am Coll Cardiol 50 1835 40
19. CW Yancy H Krum BM Massie 2008 Safety and efficacy of outpatient nesiritide in patients with advanced heart failure: Results of the second follow-up serial infusions of nesiritide (FUSION II) trial Circ Heart Fail 1 9 16
20. RM Mentzer Jr MC Oz RN Sladen 2007 Effects of perioperative nesiritide in patients with left ventricular dysfunction undergoing cardiac surgery:the NAPA Trial J Am Coll Cardiol 49 716 26