Immunohistochemical workup of sentinel nodes in endometrial cancer improves diagnostic accuracy

Gynecologic Oncology

Volumn 114, Issue 2, 2009, Pages 284-287

  Altgassen, Christopher ^a   Müller, Nadine ^a   Hornemann, Amadeus ^a   Kavallaris, Andreas ^a   Hornung, Daniela ^a   Diedrich, Klaus ^a   Jarutat, Tiantom ^b  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b Institute of Pathology   (Germany)

Author keywords

Endometrial cancer; Micrometastases; Sentinel node

Indexed keywords

DISULFINE BLUE; EOSIN; HEMATOXYLIN;

ADULT; AGED; ARTICLE; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ENDOMETRIUM CANCER; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYSTERECTOMY; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; LYMPH NODE METASTASIS; PARAAORTIC LYMPH NODE; PELVIS LYMPH NODE; PRIORITY JOURNAL; SALPINGOOOPHORECTOMY; SENSITIVITY AND SPECIFICITY; SENTINEL LYMPH NODE;

AGED; AGED, 80 AND OVER; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; SENSITIVITY AND SPECIFICITY; SENTINEL LYMPH NODE BIOPSY;

EID: 67549127100     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2009.04.020     Document Type: Article

References (28)

1. Berek J., and Hacker N. Practical Gynecologic Oncology (2005), Lippincott Williams & Wilkins, Philadelphia
2. Creasman W., Odicino F., Maisonneuve P., et al. FIGO annual report-Carcinoma of the corpus uteri. J. Epidemiol. Biostat. 6 (2001) 47-86
3. Kilgore L.C., Partridge E.E., Alvarez R.D., et al. Adenocarcinoma of the endometrium: survival comparisons of patients with and without pelvic node sampling. Gynecol. Oncol. 56 (1995) 29-33
4. Gonzalez Bosquet J., Keeney G.L., Mariani A., Webb M.J., and Cliby W.A. Cytokeratin staining of resected lymph nodes may improve the sensitivity of surgical staging for endometrial cancer. Gynecol. Oncol. 91 (2003) 518-525
5. Mohan D.S., Samuels M.A., Selim M.A., et al. Long-term outcomes of therapeutic pelvic lymphadenectomy for stage I endometrial adenocarcinoma. Gynecol. Oncol. 70 (1998) 165-171
6. Sehouli J., Camara O., Stengel D., Kohler G., and Lichtenegger W. [Multi-institutional survey on the value of lymphadenectomy in endometrial carcinoma in Germany]. Gynakol. Geburtshilfliche. Rundsch. 43 (2003) 104-110
7. Chuang L., Burke T.W., Tornos C., et al. Staging laparotomy for endometrial carcinoma: assessment of retroperitoneal lymph nodes. Gynecol. Oncol. 58 (1995) 189-193
8. Morrow C.P., Bundy B.N., Kurman R.J., et al. Relationship between surgical-pathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium: a Gynecologic Oncology Group study. Gynecol. Oncol. 40 (1991) 55-65
9. Franchi M., Ghezzi F., Riva C., Miglierina M., Buttarelli M., and Bolis P. Postoperative complications after pelvic lymphadenectomy for the surgical staging of endometrial cancer. J. Surg. Oncol. 78 (2001) 232-237 discussion 7-40
10. Niikura H., Okamoto S., Yoshinaga K., et al. Detection of micrometastases in the sentinel lymph nodes of patients with endometrial cancers. Gynecol. Oncol. 105 (2007) 683-686
11. Altgassen C., Pagenstecher J., Hornung D., Diedrich K., and Hornemann A. A new approach to label sentinel nodes in endometrial cancer. Gynecol. Oncol. 105 (2007) 457-461
12. Singletary S.E., Allred C., Ashley P., et al. Staging system for breast cancer: revisions for the 6th edition of the AJCC Cancer Staging Manual. Surg. Clin. North Am. 83 (2003) 803-819
13. Alexander-Sefre F., Singh N., Ayhan A., Salveson H.B., Wilbanks G., and Jacobs I.J. Detection of tumour lymphovascular space invasion using dual cytokeratin and CD31 immunohistochemistry. J. Clin. Pathol. 56 (2003) 786-788
14. Liu F.H., Wang Y.F., Wang J., Xue Q., Jiang S., and Ma Y.Y. [Study on cytokeratin and CA125 for diagnosing lymph node micrometastases in endometrial cancer]. Zhonghua Fu Chan Ke Za Zhi 39 (2004) 612-615
15. Fishman A., Klein A., Zemer R., et al. Detection of micrometastasis by cytokeratin-20 (reverse transcription polymerase chain reaction) in lymph nodes of patients with endometrial cancer. Gynecol. Oncol. 77 (2000) 399-404
16. Rampaul R.S., Miremadi A., Pinder S.E., Lee A., and Ellis I.O. Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer. Breast Cancer Res. 3 (2001) 113-116
17. Delpech Y., Cortez A., Coutant C., et al. The sentinel node concept in endometrial cancer: histopathologic validation by serial section and immunohistochemistry. Ann. Oncol. 18 (2007) 1799-1803
18. Amezcua C.A., MacDonald H.R., Lum C.A., et al. Endometrial cancer patients have a significant risk of harboring isolated tumor cells in histologically negative lymph nodes. Int. J. Gynecol. Cancer 16 (2006) 1336-1341
19. Yabushita H., Shimazu M., Yamada H., et al. Occult lymph node metastases detected by cytokeratin immunohistochemistry predict recurrence in node-negative endometrial cancer. Gynecol. Oncol. 80 (2001) 139-144
20. Niikura H., Okamura C., Utsunomiya H., et al. Senitnel lymph node detection in patients with endometrial cancer. Gynecol Oncol 92 (2004) 669-674
21. Burke T.W., Levenback C., Tornos C., Morris M., Wharton J.T., and Gershenson D.M. Intraabdominal lymphatic mapping to direct selective pelvic and paraaortic lymphadenectomy in women with high-risk endometrial cancer: results of a pilot study. Gynecol. Oncol. 62 (1996) 169-173
22. Raspagliesi F., Ditto A., Kusamura S., et al. Hysteroscopic injection of tracers in sentinel node detection of endometrial cancer: a feasibility study. Am. J. Obstet. Gynecol. 191 (2004) 435-439
23. Maccauro M., Lucignani G., Aliberti G., et al. Sentinel lymph node detection following the hysteroscopic peritumoural injection of 99mTc-labelled albumin nanocolloid in endometrial cancer. Eur. J. Nucl. Med. Mol. Imaging 32 (2005) 569-574
24. Pelosi E., Arena V., Baudino B., et al. Preliminary study of sentinel node identification with 99mTc colloid and blue dye in patients with endometrial cancer. Tumori 88 (2002) S9-10
25. Pelosi E., Arena V., Baudino B., et al. Pre-operative lymphatic mapping and intra-operative sentinel lymph node detection in early stage endometrial cancer. Nucl. Med. Commun. 24 (2003) 971-975
26. Ballester M., Dubernard G., Rouzier R., Barranger E., and Darai E. Use of the sentinel node procedure to stage endometrial cancer. Ann. Surg. Oncol. 15 (2008) 1523-1529
27. Lelievre L., Camatte S., Le Frere-belda M.A., et al. Sentinel lymph node biopsy in cervix and corpus uteri cancers. Int. J. Gynecol. Cancer 14 (2004) 271-278
28. Niikura H., Okamura C., Utsunomiya H., et al. Sentinel lymph node detection in patients with endometrial cancer. Gynecol. Oncol. 92 (2004) 669-674