메뉴 건너뛰기




Volumn , Issue , 2008, Pages

Translating multiscale cancer models into clinical trials: Simulating breast cancer tumor dynamics within the framework of the "Trial of Principle" clinical trial and the ACGT project

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; BREAST CANCER TUMORS; CANCER MODELS; CANCER TREATMENT; CLINICAL DATA; CLINICAL INFORMATION; CLINICAL PRACTICES; CLINICAL TRIAL; COMPUTER MODELS; DEAD CELLS; DISCRETE STATE; DYNAMICS MODELS; EPIRUBICIN; EUROPEAN COMMISSION; IN-SILICO; MULTILEVEL MODELING; MULTISCALE; OPTIMIZATION PROCESS; TRANSITION RATES; TREATMENT OPTIMIZATION; TUMOR GROWTH;

EID: 67549122648     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/BIBE.2008.4696758     Document Type: Conference Paper
Times cited : (8)

References (17)
  • 1
    • 0038394851 scopus 로고    scopus 로고
    • World Health Organization International Agency for Research on Cancer June, Retrieved on 2008-06-17
    • World Health Organization International Agency for Research on Cancer (June 2003). World Cancer Report. Retrieved on 2008-06-17.
    • (2003) World Cancer Report
  • 3
    • 0016791386 scopus 로고
    • Mathematic models for cancer chemotherapy: Pharmacokinetic and cell kinetic considerations
    • S. Chuang, "Mathematic models for cancer chemotherapy: pharmacokinetic and cell kinetic considerations," Cancer Chemother. Rep,vol. 59, no. 4, pp. 827-42, 1975.
    • (1975) Cancer Chemother. Rep , vol.59 , Issue.4 , pp. 827-842
    • Chuang, S.1
  • 4
    • 0024327711 scopus 로고
    • Kinetic analysis of cell killing effect induced by cytosine arabinoside and cisplatin in relation to cell cycle phase specificity in human colon cancer and chinese hamster cells
    • S. Ozawa, Y. Sugiyama, J. Mitsuhashi, and M. Inaba, "Kinetic analysis of cell killing effect induced by cytosine arabinoside and cisplatin in relation to cell cycle phase specificity in human colon cancer and chinese hamster cells," Cancer Res., vol. 49, pp. 3823-3828, 1989.
    • (1989) Cancer Res , vol.49 , pp. 3823-3828
    • Ozawa, S.1    Sugiyama, Y.2    Mitsuhashi, J.3    Inaba, M.4
  • 5
    • 0036350193 scopus 로고    scopus 로고
    • Modeling multi-drug chemotherapy: Tailoring treatment to individuals
    • S. N. Gardner, "Modeling multi-drug chemotherapy: Tailoring treatment to individuals," J. Theor. Biol., vol. 214, pp. 181-207, 2002.
    • (2002) J. Theor. Biol , vol.214 , pp. 181-207
    • Gardner, S.N.1
  • 6
    • 7444252789 scopus 로고    scopus 로고
    • V. Durbecq, M. Paesmans, F. Cardoso, C. Desmedt, A. Di Leo, S. Chan, K. Friedrichs, T. Pinter, S. Van Belle, E. Murray, I. Bodrogi, E. Walpole, B. Lesperance, S. Korec, J. Crown,11 P. Simmonds, T. J. Perren, J.-Y. Leroy, G. Rouas, C. Sotiriou, M. Piccart, and D. Larsimont, Topoisomerase-IIA expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel, Mol Cancer Ther, 3, pp. 1207-1214, October 2004
    • V. Durbecq, M. Paesmans, F. Cardoso, C. Desmedt, A. Di Leo, S. Chan, K. Friedrichs, T. Pinter, S. Van Belle, E. Murray, I. Bodrogi, E. Walpole, B. Lesperance, S. Korec, J. Crown,11 P. Simmonds, T. J. Perren, J.-Y. Leroy, G. Rouas, C. Sotiriou, M. Piccart, and D. Larsimont, "Topoisomerase-IIA expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel," Mol Cancer Ther, vol. 3, pp. 1207-1214, October 2004
  • 7
    • 1542287820 scopus 로고    scopus 로고
    • G.S. Stamatakos, D.D. Dionysiou, E.I. Zacharaki, N.A. Mouravliansky, K.S.Nikita, N.K. & Uzunoglu, In silico radiation oncology: combining novel simulation algorithms with current visualization techniques, IEEE Proceedings: Special Issue on Bioinformatics: Advances and Chalenges, 90(11), 1764-1777, 2002.
    • G.S. Stamatakos, D.D. Dionysiou, E.I. Zacharaki, N.A. Mouravliansky, K.S.Nikita, N.K. & Uzunoglu, In silico radiation oncology: combining novel simulation algorithms with current visualization techniques, IEEE Proceedings: Special Issue on Bioinformatics: Advances and Chalenges, 90(11), 1764-1777, 2002.
  • 8
    • 3242707711 scopus 로고    scopus 로고
    • A four-dimensional simulation model of tumour response to radiotherapy in vivo: Parametric validation considering radiosensitivity, genetic profile and fractionation
    • D. D. Dionysiou, G. S. Stamatakos, N.K. Uzunoglu, K. S. Nikita, A. Marioli, "A four-dimensional simulation model of tumour response to radiotherapy in vivo: parametric validation considering radiosensitivity, genetic profile and fractionation,"Journal of Theoretical Biology vol. 230, pp. 1-20, 2004
    • (2004) Journal of Theoretical Biology , vol.230 , pp. 1-20
    • Dionysiou, D.D.1    Stamatakos, G.S.2    Uzunoglu, N.K.3    Nikita, K.S.4    Marioli, A.5
  • 9
    • 33746622960 scopus 로고    scopus 로고
    • A Spatiotemporal, Patient Individualized Simulation Model of Solid Tumor Response to Chemotherapy in Vivo: The Paradigm of Glioblastoma Multiforme Treated by Temozolomide
    • August
    • G. S. Stamatakos, V. P. Antipas and N. K. Uzunoglu, "A Spatiotemporal, Patient Individualized Simulation Model of Solid Tumor Response to Chemotherapy in Vivo: The Paradigm of Glioblastoma Multiforme Treated by Temozolomide," IEEE Transactions On Biomedical Engineering, vol. 53, pp. 1467- 1477, August 2006
    • (2006) IEEE Transactions On Biomedical Engineering , vol.53 , pp. 1467-1477
    • Stamatakos, G.S.1    Antipas, V.P.2    Uzunoglu, N.K.3
  • 10
    • 78449294939 scopus 로고    scopus 로고
    • G.S. Stamatakos, D.D. Dionysiou, N.M. Graf, N.A. Sofra, C. Desmedt, A. Hoppe, N. Uzunoglu, M. Tsiknakis, The Oncosimulator: a multilevel, clinically oriented simulation system of tumor growth and organism response to therapeutic schemes. Towards the clinical evaluation of in silico oncology, Proceedings of the 29th Annual International Conference of the IEEE EMBS Cite Internationale, August 23-26, SuB07.1: 6628-6631, Lyon, France, 2007
    • G.S. Stamatakos, D.D. Dionysiou, N.M. Graf, N.A. Sofra, C. Desmedt, A. Hoppe, N. Uzunoglu, M. Tsiknakis, "The Oncosimulator: a multilevel, clinically oriented simulation system of tumor growth and organism response to therapeutic schemes. Towards the clinical evaluation of in silico oncology," Proceedings of the 29th Annual International Conference of the IEEE EMBS Cite Internationale, August 23-26, SuB07.1: 6628-6631, Lyon, France, 2007
  • 11
    • 67549089505 scopus 로고    scopus 로고
    • G. Steel, Basic Clinical Radiobiology. Arnold, London, UK. 2002.
    • G. Steel, Basic Clinical Radiobiology. Arnold, London, UK. 2002.
  • 12
    • 0010417993 scopus 로고    scopus 로고
    • Cancer Chemotherapy
    • B.G. Katzung, ed. Lange Medical Books/McGraw-Hill, International Edition, pp
    • S.E.Salmon and A.C.Sartorelli "Cancer Chemotherapy", in Basic & Clinical Pharmacology, B.G. Katzung, ed. Lange Medical Books/McGraw-Hill, International Edition, pp.923-1044, 2001.
    • (2001) Basic & Clinical Pharmacology , pp. 923-1044
    • Salmon, S.E.1    Sartorelli, A.C.2
  • 14
    • 67549092960 scopus 로고    scopus 로고
    • http://depts.washington.edu/saam2/
  • 15
    • 0003499531 scopus 로고    scopus 로고
    • M.C.Perry ed, USA, Philadelphia: Lippincott Williams &Wilkins
    • M.C.Perry ed. The Chemotherapy Source Book. USA, Philadelphia: Lippincott Williams &Wilkins, 2008.
    • (2008) The Chemotherapy Source Book
  • 16
    • 67549098082 scopus 로고    scopus 로고
    • http://www.fda.gov/cder/foi/nda/99/50-778-Ellence-pharmr.pdf


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.