메뉴 건너뛰기




Volumn 46, Issue 12, 2008, Pages 805-810

Relaxant effects of different fractions from Nigella sativa L. on guinea pig tracheal chains and its possible mechanism(s)

Author keywords

Bronchodilatory; Fractions; Guinea pig; Nigella sativa; Trachea

Indexed keywords

CAVIA; NIGELLA SATIVA;

EID: 67549093936     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (32)

References (29)
  • 1
    • 0000988920 scopus 로고
    • Studies on chemical constitution of Egyptian Nigella sativa L.seeds. II: The essential oil
    • El-Dakhakhny M, Studies on chemical constitution of Egyptian Nigella sativa L.seeds. II: The essential oil, Planta Medica, 11 (1963) 465.
    • (1963) Planta Medica , vol.11 , pp. 465
    • El-Dakhakhny, M.1
  • 2
    • 0028954707 scopus 로고
    • Nigellidine, a new indazol alkaloid from seeds of Nigella sativa
    • Atta U R & Malik S O, Nigellidine, a new indazol alkaloid from seeds of Nigella sativa, Tetrahedron Let, 36 (1995) 1993.
    • (1995) Tetrahedron Let , vol.36 , pp. 1993
    • Atta, U.R.1    Malik, S.O.2
  • 3
    • 0000926036 scopus 로고
    • Nigellimine N-oxide a new isoquinoline alkaloid from the seeds of Nigella sativa
    • Atta U R & Malik S O, Nigellimine N-oxide, a new isoquinoline alkaloid from the seeds of Nigella sativa, Hetrocycles, 23 (1985) 953.
    • (1985) Hetrocycles , vol.23 , pp. 953
    • Atta, U.R.1    Malik, S.O.2
  • 4
    • 0001504914 scopus 로고
    • Structural studies on a saponin isolated from the seeds of Nigella sativa
    • Ansari A K & Sadiy H A S, Structural studies on a saponin isolated from the seeds of Nigella sativa, Phyto Chem, 7 (1989) 377.
    • (1989) Phyto Chem , vol.7 , pp. 377
    • Ansari, A.K.1    Sadiy, H.A.S.2
  • 5
    • 27744476617 scopus 로고    scopus 로고
    • Immunomodulatory and therapeutic properties of the Nigella sativa L. seed
    • Labib Salem M, Immunomodulatory and therapeutic properties of the Nigella sativa L. seed, International Immunopharmacol, 5 (2005) 1749.
    • (2005) International Immunopharmacol , vol.5 , pp. 1749
    • Labib, S.M.1
  • 6
    • 0013438813 scopus 로고
    • Interpreter, Ministry of Culture publication, Teheran
    • Ave-Sina, Law in Medicine, Sharafkhandy A; Interpreter, Ministry of Culture publication, Teheran (1990) 314.
    • (1990) Law in Medicine , pp. 314
    • Ave-Sina1    Sharafkhandy, A.2
  • 7
    • 0002896616 scopus 로고
    • The relaxing effect of volatile oil of Nigella sativa seed on vascular smooth muscle
    • Aqel M B, The relaxing effect of volatile oil of Nigella sativa seed on vascular smooth muscle, Jordan Ser B, 1 (1992) 91.
    • (1992) Jordan Ser B , vol.1 , pp. 91
    • Aqel, M.B.1
  • 8
    • 0027225495 scopus 로고
    • Effects of Nigella sativa seeds on intestinal smooth muscle
    • Aqel M B, Effects of Nigella sativa seeds on intestinal smooth muscle, Int J Pharmacogn, 31 (1993) 55.
    • (1993) Int J Pharmacogn , vol.31 , pp. 55
    • Aqel, M.B.1
  • 9
    • 0022000669 scopus 로고
    • Relaxant effects on tracheal and ileal smooth muscles of the guinea pig.
    • Reiter M & Brandt W, Relaxant effects on tracheal and ileal smooth muscles of the guinea pig., Arzneim Forsch Drug Res, 35 (1985) 408.
    • (1985) Arzneim Forsch Drug Res , vol.35 , pp. 408
    • Reiter, M.1    Brandt, W.2
  • 10
    • 0001651107 scopus 로고
    • Chemical and pharmacological properties of the new anti-asthmatic drug, nigellone
    • Mahfouz M & El-Dakhakhny M, Chemical and pharmacological properties of the new anti-asthmatic drug, nigellone, Egypt Pharm Bull, 42 (1960) 411.
    • (1960) Egypt Pharm Bull , vol.42 , pp. 411
    • Mahfouz, M.1    El-Dakhakhny, M.2
  • 11
    • 2342626583 scopus 로고    scopus 로고
    • Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug
    • Hajhashemi V, Ghannadi A & Jafarabadi H, Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug, Phytothe Res, 18 (2004) 195.
    • (2004) Phytothe Res , vol.18 , pp. 195
    • Hajhashemi, V.1    Ghannadi, A.2    Jafarabadi, H.3
  • 13
    • 0031396009 scopus 로고    scopus 로고
    • Bronchodilatory and anticholinergic effects of Nigella sativa on isolated guineapig tracheal chains
    • Boskabady M H & Shahabi M, Bronchodilatory and anticholinergic effects of Nigella sativa on isolated guineapig tracheal chains, Iran J Med Sci, 22 (1997) 127.
    • (1997) Iran J Med Sci , vol.22 , pp. 127
    • Boskabady, M.H.1    Shahabi, M.2
  • 14
    • 0037003174 scopus 로고    scopus 로고
    • 1) receptors of isolated guinea pig tracheal chains
    • 1) receptors of isolated guinea pig tracheal chains, Pharmac Biol, 40 (2002) 596.
    • (2002) Pharmac Biol , vol.40 , pp. 596
    • Boskabady, M.H.1    Shiravi, N.2
  • 15
    • 0036054596 scopus 로고    scopus 로고
    • Effect of Nigella Sativa on isolated guinea pig tracheal chains
    • Boskabady M H & Shirmohammadi B, Effect of Nigella Sativa on isolated guinea pig tracheal chains, Arch Iram Med, 5 (2002) 103.
    • (2002) Arch Iram Med , vol.5 , pp. 103
    • Boskabady, M.H.1    Shirmohammadi, B.2
  • 16
    • 2642534478 scopus 로고    scopus 로고
    • Possible mechanisms for relaxant effect of aqueous and macerate extracts from Nigella sativa on tracheal chains of guinea pig
    • Boskabady M H, Shirmohammadi B, Jandaghi P & Kiani S, Possible mechanisms for relaxant effect of aqueous and macerate extracts from Nigella sativa on tracheal chains of guinea pig, BMC Pharmacol, 4 (2004) 3.
    • (2004) BMC Pharmacol , vol.4 , pp. 3
    • Boskabady, M.H.1    Shirmohammadi, B.2    Jandaghi, P.3    Kiani, S.4
  • 19
    • 0022976097 scopus 로고
    • The influence of epithelium on the responsiveness of guinea-pig isolated trachea
    • Holroyde M C, The influence of epithelium on the responsiveness of guinea-pig isolated trachea, British J Pharmacol, 87 (1986) 501.
    • (1986) British J Pharmacol , vol.87 , pp. 501
    • Holroyde, M.C.1
  • 20
    • 0028168548 scopus 로고
    • Beta3 adrenoceptor agonists, BRL 37344 and SR 58611A do not induce relaxation of human, sheep and guinea-pig airway smooth muscle in vitro
    • Martin C A E, Naline E, Bakdach H & Advenier C, Beta3 adrenoceptor agonists, BRL 37344 and SR 58611A do not induce relaxation of human, sheep and guinea-pig airway smooth muscle in vitro, Eur Respir J, 7 (1994) 1610.
    • (1994) Eur Respir J , vol.7 , pp. 1610
    • Martin, C.A.E.1    Naline, E.2    Bakdach, H.3    Advenier, C.4
  • 21
    • 0027379427 scopus 로고
    • Effect of organic and inorganic Ca2+ antagonists on acetylcholine induced contraction in molluscan (Mytilus edulis) smooth muscle
    • Miyahara Y, Kizawa Y, Sano M & Murakami H, Effect of organic and inorganic Ca2+ antagonists on acetylcholine induced contraction in molluscan (Mytilus edulis) smooth muscle, General Pharmacol, 24 (1993) 1419.
    • (1993) General Pharmacol , vol.24 , pp. 1419
    • Miyahara, Y.1    Kizawa, Y.2    Sano, M.3    Murakami, H.4
  • 22
    • 0027329968 scopus 로고
    • Effect of two Ca2+ modulator in normal and albumin sensitized guinea pig trachea
    • McCaig D & DeJonckeere S, Effect of two Ca2+ modulator in normal and albumin sensitized guinea pig trachea, Eur J Pharmacol, 249 (1993) 53.
    • (1993) Eur J Pharmacol , vol.249 , pp. 53
    • McCaig, D.1    DeJonckeere, S.2
  • 23
    • 0027399234 scopus 로고
    • Relaxation effect of potassium channel activators BRL 38227 and Pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by Glibenclamide and BRL 31660
    • Buckle D R, Arch J R S, Boering N E, Foster K A, Taylor J F, Taylor S G & Shaw D J, Relaxation effect of potassium channel activators BRL 38227 and Pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by Glibenclamide and BRL 31660, Pulmon Pharmacol, 6 (1993) 77.
    • (1993) Pulmon Pharmacol , vol.6 , pp. 77
    • Buckle, D.R.1    Arch, J.R.S.2    Boering, N.E.3    Foster, K.A.4    Taylor, J.F.5    Taylor, S.G.6    Shaw, D.J.7
  • 25
    • 0028074792 scopus 로고
    • Cyclic nucleotide phosphodiesterases in the human lung
    • Dent G, Magnussen H & Rabe K, Cyclic nucleotide phosphodiesterases in the human lung. Lung, 172(1994) 129-146.
    • (1994) Lung , vol.172 , pp. 129-146
    • Dent, G.1    Magnussen, H.2    Rabe, K.3
  • 26
    • 0033052113 scopus 로고    scopus 로고
    • Recent advances in our understanding of the use of theophylline in the treatment of asthma
    • Page C P, Recent advances in our understanding of the use of theophylline in the treatment of asthma. J Clin Pharmacol, 39(1999) 237.
    • (1999) J Clin Pharmacol , vol.39 , pp. 237
    • Page, C.P.1
  • 27
    • 0031879999 scopus 로고    scopus 로고
    • Theophylline and airway inflammation
    • Rabe K F & Dent G, Theophylline and airway inflammation. Clin Exp Allergy, 28 (SUPPL. 3) (1998) 35.
    • (1998) Clin Exp Allergy , vol.28 , Issue.SUPPL. 3 , pp. 35
    • Rabe, K.F.1    Dent, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.