The role of positive flow cytometry crossmatch in late renal allograft loss

Human Immunology

Volumn 70, Issue 7, 2009, Pages 502-505

  Graff, Ralph J ^a,b   Xiao, Huiling ^c   Schnitzler, Mark A ^c   Ercole, Patrick ^c   Solomon, Harvey ^b   Pessin, Tracy ^c   Lentine, Krista L ^c  

^a Division of Abdominal Organ Transplantation   (United States)

^b S LOUIS UNIV HLTH SCIENCES CENTER   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Crossmatch; Flow cytometry crossmatch; Graft failure; Kidney transplant; Registries

Indexed keywords

ARTICLE; B LYMPHOCYTE; BLOOD GROUP TYPING; CADAVER DONOR; CELL DAMAGE; CONTROLLED STUDY; EFFECTOR CELL; FLOW CYTOMETRY; HUMAN; KIDNEY TRANSPLANTATION; LIVING DONOR; MEMORY CELL; OUTCOME ASSESSMENT; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RENAL GRAFT DYSFUNCTION; RISK ASSESSMENT; T LYMPHOCYTE;

B-LYMPHOCYTES; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; GRAFT REJECTION; GRAFT SURVIVAL; HISTOCOMPATIBILITY TESTING; HUMANS; KAPLAN-MEIER ESTIMATE; KIDNEY TRANSPLANTATION; REGISTRIES; T-LYMPHOCYTES; TISSUE AND ORGAN PROCUREMENT; TRANSPLANTATION, HOMOLOGOUS;

EID: 67449168130     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2009.04.002     Document Type: Article

References (11)

1. Patel R., and Terasaki P.I. Significance of the positive crossmatch test in kidney transplantation. N Engl J Med 280 (1969) 735-739
2. Lentine K.L., Graff R.J., Xiao H., Modanlou K.A., Salvalaggio P.R., Brennan D.C., et al. Flow cytometry crossmatch before kidney transplantation in contemporary practice: target cell utilization, results patterns, and associated long-term graft survival. Clin Transpl (2008) 253-266
3. Gebel H.M., Bray R.A., and Nickerson P. Pre-transplant assessment of donor-reactive, HLA-specific antibodies in renal transplantation: contraindication vs. risk. Am J Transplant 3 (2003) 1488-1500
4. Wilmonton-Hosey L., Chapman P., Holcomb J., and Bray R. Flow cytometry crossmatch and antibody detection. ASHI Laboratory Manual (2000) B.1.
5. Mahoney R.J., Ault K.A., Given S.R., Adams R.J., Breggia A.C., Paris P.A., et al. The flow cytometric crossmatch and early renal transplant loss. Transplantation 49 (1990) 527-535
6. Eng H.S., Bennett G., Tsiopelas E., Lake M., Humphreys I., Chang S.H., et al. Anti-HLA donor-specific antibodies detected in positive B-cell crossmatches by Luminex predict late graft loss. Am J Transplant 8 (2008) 2335-2342
7. Scornik J.C., LeFor W.M., Cicciarelli J.C., Brunson M.E., Bogaard T., Howard R.J., et al. Hyperacute and acute kidney graft rejection due to antibodies against B cells. Transplantation 54 (1992) 61-64
8. Comeaux A., Rogers J., Lavingia B., and Stastny P. Effect of donor-specific HLA antibodies and B-cell flow XM on outcome of renal transplants. Hum Immunol 69 (2008) S22
9. Kaliss N. Immunological enhancement and inhibition of tumor growth: relationship to various immunological mechanisms. Fed Proc 24 (1965) 1024-1029
10. Newton W.T., and Anderson C.B. Planned preimmunization of renal allograft recipients. Surgery 74 (1973) 430-436
11. Jordan S.C., Tyan D., Stablein D., McIntosh M., Rose S., Vo A., et al. Evaluation of intravenous immunoglobulin as an agent to lower allosensitization and improve transplantation in highly sensitized adult patients with end-stage renal disease: report of the NIH IG02 trial. J Am Soc Nephrol 15 (2004) 3256-3262