Biomarker discovery in glomerular diseases using urinary proteomics

Proteomics - Clinical Applications

Volumn 2, Issue 10-11, 2008, Pages 1413-1421

  Thongboonkerd, Visith ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Biomarker discovery; Glomerular; Glomerulonephritis; Kidney

Indexed keywords

ALBUMIN; ALPHA 1 ANTITRYPSIN; ALPHA 1 MICROGLOBULIN; ALPHA2 GLYCOPROTEIN; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; BIOLOGICAL MARKER; HAPTOGLOBIN; HEMOPEXIN; IMMUNOGLOBULIN A; OROSOMUCOID; PREALBUMIN; RETINOL BINDING PROTEIN; TRANSFERRIN; UNCLASSIFIED DRUG; ZINC ALPHA2 GLYCOPROTEIN;

ALBUMIN BLOOD LEVEL; BODY FLUID; DIABETIC NEUROPATHY; FOCAL GLOMERULOSCLEROSIS; GLOMERULOPATHY; GOODPASTURE SYNDROME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOASSAY; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY DISEASE; LUPUS ERYTHEMATOSUS NEPHRITIS; MASS SPECTROMETRY; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; MEMBRANOUS GLOMERULONEPHRITIS; MICROALBUMINURIA; MICROFLUIDIC ANALYSIS; NEPHRITIS; NEPHROTIC SYNDROME; NON INVASIVE PROCEDURE; NONHUMAN; PASSIVE HEYMANN NEPHRITIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; PROTEINURIA; PROTEOMICS; REVIEW; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS; URINALYSIS; URINARY EXCRETION; URINE LEVEL;

EID: 67449141120     PISSN: 18628346     EISSN: None     Source Type: Journal    
DOI: 10.1002/prca.200800036     Document Type: Review

References (63)

1. Fuiano, G., Mazza, G., Comi, N., Caglioti, A. et al., Current indications for renal biopsy: A questionnaire-based survey. Am. J. Kidney Dis. 2000, 35, 448-457.
2. Whittier, W. L., Korbet, S. M., Renal biopsy: Update. Curr. Opin. Nephrol. Hypertens. 2004, 13, 661-665.
3. Amann, K., Haas, C. S., What you should know about the work-up of a renal biopsy. Nephrol. Dial. Transplant. 2006, 21, 1157-1161.
4. Walker, P. D., Cavallo, T., Bonsib, S. M., Practice guidelines for the renal biopsy. Mod. Pathol. 2004, 17, 1555-1563.
5. Seeley, E. H., Caprioli, R. M., Imaging mass spectrometry: Towards clinical diagnostics. Proteomics Clin. Appl. 2008, 2, doi: 10.1002/prca.200800013.
6. Xu, X., Veenstra, T. D., Analysis of biofluids for biomarker research. Proteomics Clin. Appl. 2008, 2, doi: 10.1002/ prca.200780173.
7. Good, D. M., Thongboonkerd, V., Novak, J., Bascands, J. L. et al., Body fluid proteomics for biomarker discovery: Lessons from the past hold the key to success in the future. J Proteome. Res. 2007, 6, 4549-4555.
8. Ping, P., Vondriska, T. M., Creighton, C. J., Gandhi, T. K. et al., A functional annotation of subproteomes in human plasma. Proteomics 2005, 5, 3506-3519.
9. Anderson, N. L., Anderson, N. G., The human plasma proteome: History, character, and diagnostic prospects. Mol. Cell. Proteomics 2002, 1, 845-867.
10. Marshall, T., Williams, K. M., Electrophoretic analysis of Bence Jones proteinuria. Electrophoresis 1999, 20, 1307-1324.
11. Stone, M. J., Henry Bence Jones and his protein. J. Med. Biogr. 1998, 6, 53-57.
12. Kyle, R. A., The monoclonal gammopathies. Clin. Chem. 1994, 40, 2154-2161.
13. Veenstra, T. D., Global and targeted quantitative proteomics for biomarker discovery. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci 2007, 847, 3-11.
14. Duncan, M. W., Hunsucker, S. W., Proteomics as a tool for clinically relevant biomarker discovery and validation. Exp. Biol. Med. (Maywood) 2005, 230, 808-817.
15. Thongboonkerd, V., Recent progress in urinary proteomics. Proteomics Clin. Appl. 2007, 1, 780-791.
16. Tryggvason, K., Pettersson, E., Causes and consequences of proteinuria: The kidney filtration barrier and progressive renal failure. J. Intern. Med. 2003, 254, 216-224.
17. D'Amico, G., Bazzi, C., Pathophysiology of proteinuria. Kidney Int. 2003, 63, 809-825.
18. Foley, R. N., Collins, A. J., End-stage renal disease in the United States: An update from the United States Renal Data System. J. Am. Soc. Nephrol. 2007, 18, 2644-2648.
19. Caramori, M. L., Fioretto, P., Mauer, M., The need for early predictors of diabetic nephropathy risk: Is albumin excretion rate sufficient? Diabetes 2000, 49, 1399-1408.
20. Chavers, B. M., Bilous, R.W., Ellis, E. N., Steffes, M.W. et al., Glomerular lesions and urinary albumin excretion in type I diabetes without overt proteinuria. N. Engl. J. Med. 1989, 320, 966-970.
21. Fioretto, P., Steffes, M. W., Mauer, M., Glomerular structure in nonproteinuric IDDM patients with various levels of albuminuria. Diabetes 1994, 43, 1358-1364.
22. Bangstad, H. J., Osterby, R., Dahl-Jorgensen, K., Berg, K. J. et al., Early glomerulopathy is present in young, type 1 (insulin-dependent) diabetic patients with microalbuminuria. Diabetologia 1993, 36, 523-529.
23. Comper, W. D., Osicka, T.M., Jerums, G., High prevalence of immuno-unreactive intact albumin in urine of diabetic patients. Am. J. Kidney Dis. 2003, 41, 336-342.
24. Candiano, G., Musante, L., Bruschi, M., Petretto, A. et al., Repetitive fragmentation products of albumin and alpha1-antitrypsin in glomerular diseases associated with nephrotic syndrome. J. Am. Soc. Nephrol. 2006, 17, 3139-3148.
25. Thongboonkerd, V., Klein, J. B., Jevans, A. W., McLeish, K. R., Urinary proteomics and biomarker discovery for glomerular diseases. Contrib. Nephrol. 2004, 141, 292-307.
26. Varghese, S. A., Powell, T. B., Budisavljevic, M. N., Oates, J. C. et al., Urine biomarkers predict the cause of glomerular disease. J. Am. Soc. Nephrol. 2007, 18, 913-922.
27. Sharma, K., Lee, S., Han, S., Lee, S. et al., Two-dimensional fluorescence difference gel electrophoresis analysis of the urine proteome in human diabetic nephropathy. Proteomics 2005, 5, 2648-2655.
28. Rao, P. V., Lu, X., Standley, M., Pattee, P. et al., Proteomic identification of urinary biomarkers of diabetic nephropathy. Diabetes Care 2007, 30, 629-637.
29. Dihazi, H., Muller, G. A., Lindner, S., Meyer, M. et al., Characterization of diabetic nephropathy by urinary proteomic analysis: Identification of a processed ubiquitin form as a differentially excreted protein in diabetic nephropathy patients. Clin. Chem. 2007, 53, 1636-1645.
30. Otu, H. H., Can, H., Spentzos, D., Nelson, R. G. et al., Prediction of diabetic nephropathy using urine proteomic profiling 10 years prior to development of nephropathy. Diabetes Care 2007, 30, 638-643.
31. Meier, M., Kaiser, T., Herrmann, A., Knueppel, S. et al., Identification of urinary protein pattern in type 1 diabetic adolescents with early diabetic nephropathy by a novel combined proteome analysis. J. Diabetes Complicat. 2005, 19, 223-232.
32. Mischak, H., Kaiser, T., Walden, M., Hillmann, M. et al., Proteomic analysis for the assessment of diabetic renal damage in humans. Clin. Sci (Lond) 2004, 107, 485-495.
33. Tudos, A. J., Besselink, G. J., Schasfoort, R. B., Trends in miniaturized total analysis systems for point-of-care testing in clinical chemistry. Lab Chip 2001, 1, 83-95.
34. Verpoorte, E., Microfluidic chips for clinical and forensic analysis. Electrophoresis 2002, 23, 677-712.
35. Whitesides, G. M., The origins and the future of microfluidics. Nature 2006, 442, 368-373.
36. Lion, N., Reymond, F., Girault, H. H., Rossier, J. S., Why the move to microfluidics for protein analysis? Curr. Opin. Biotechnol. 2004, 15, 31-37.
37. Srinivasan, V., Pamula, V. K., Fair, R. B., An integrated digital microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids. Lab Chip 2004, 4, 310-315.
38. Minas, G., Wolffenbuttel, R. F., Correia, J. H., A lab-on-a-chip for spectrophotometric analysis of biological fluids. Lab Chip 2005, 5, 1303-1309.
39. Thongboonkerd, V., Songtawee, N., Sritippayawan, S., Urinary proteome profiling using microfluidic technology on a chip. J. Proteome Res. 2007, 6, 2011-2018.
40. Barratt, J., Feehally, J., IgA nephropathy. J. Am. Soc. Nephrol. 2005, 16, 2088-2097.
41. Julian, B. A., Wittke, S., Haubitz, M., Zurbig, P. et al., Urinary biomarkers of IgA nephropathy and other IgA-associated renal diseases. World J. Urol. 2007, 25, 467-476.
42. Park, M. R., Wang, E. H., Jin, D. C., Cha, J. H. et al., Establishment of a 2-D human urinary proteomic map in IgA nephropathy. Proteomics 2006, 6, 1066-1076.
43. Yokota, H., Hiramoto, M., Okada, H., Kanno, Y. et al., Absence of increased alpha1-microglobulin in IgA nephropathy proteinuria. Mol. Cell. Proteomics 2007, 6, 738-744.
44. Haubitz, M., Wittke, S., Weissinger, E. M., Walden, M. et al., Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy. Kidney Int. 2005, 67, 2313-2320.
45. Rocchetti, M. T., Centra, M., Papale, M., Bortone, G. et al., Urine protein profile of IgA nephropathy patients may predict the response to ACE-inhibitor therapy. Proteomics 2008, 8, 206-216.
46. Ronco, P., Debiec, H., Molecular pathomechanisms of membranous nephropathy: From Heymann nephritis to alloimmunization. J Am. Soc. Nephrol. 2005, 16, 1205-1213.
47. Wasserstein, A. G., Membranous glomerulonephritis. J. Am. Soc. Nephrol. 1997, 8, 664-674.
48. Glassock, R. J., Diagnosis and natural course of membranous nephropathy. Semin. Nephrol. 2003, 23, 324-332.
49. Ngai, H. H., Sit, W. H., Jiang, P. P., Xu, R. J. et al., Serial changes in urinary proteome profile of membranous nephropathy: Implications for pathophysiology and biomarker discovery. J. Proteome Res. 2006, 5, 3038-3047.
50. Ngai, H. H., Sit, W. H., Jiang, P. P., Thongboonkerd, V. et al., Markedly increased urinary preprohaptoglobin and haptoglobin in passive heymann nephritis: A differential proteomics approach. J. Proteome Res. 2007, 6, 3313-3320.
51. Shui, H. A., Huang, T. H., Ka, S. M., Chen, P. H. et al., Urinary proteome and potential biomarkers associated with serial pathogenesis steps of focal segmental glomerulosclerosis. Nephrol. Dial. Transplant. 2008, 23, 176-185.
52. Appel, G. B., Cook, H. T., Hageman, G., Jennette, J. C. et al., Membranoproliferative glomerulonephritis type II (dense deposit disease): An update. J. Am. Soc. Nephrol. 2005, 16, 1392-1403.
53. Braun, M. C., Li, L., Ke, B., Dubinsky, W. P. et al., Proteomic profiling of urinary protein excretion in the factor H-deficient mouse. Am. J. Nephrol. 2006, 26, 127-135.
54. Rovin, B. H., Birmingham, D. J., Nagaraja, H. N., Yu, C. Y. et al., Biomarker discovery in human SLE nephritis. Bull. NYU Hosp. Jt. Dis. 2007, 65, 187-193.
55. Suzuki, M., Ross, G. F., Wiers, K., Nelson, S. et al., Identification of a urinary proteomic signature for lupus nephritis in children. Pediatr. Nephrol. 2007, 22, 2047-2057.
56. Mosley, K., Tam, F. W., Edwards, R. J., Crozier, J. et al., Urinary proteomic profiles distinguish between active and inactive lupus nephritis. Rheumatology (Oxford) 2006, 45, 1497-1504.
57. Wu, T., Xie, C., Bhaskarabhatla, M., Yan, M. et al., Excreted urinary mediators in an animal model of experimental immune nephritis with potential pathogenic significance. Arthritis Rheum. 2007, 56, 949-959.
58. Xie, C., Zhou, X. J., Liu, X., Mohan, C., Enhanced susceptibility to end-organ disease in the lupus-facilitating NZW mouse strain. Arthritis Rheum. 2003, 48, 1080-1092.
59. Xie, C., Sharma, R., Wang, H., Zhou, X. J. et al., Strain distribution pattern of susceptibility to immune-mediated nephritis. J. Immunol. 2004, 172, 5047-5055.
60. Lowenborg, E. K., Jaremko, G., Berg, U. B., Glomerular function and morphology in puromycin aminonucleoside nephropathy in rats. Nephrol. Dial. Transplant. 2000, 15, 1547-1555.
61. Cutler, P., Bell, D. J., Birrell, H. C., Connelly, J. C. et al., An integrated proteomic approach to studying glomerular nephrotoxicity. Electrophoresis 1999, 20, 3647-3658.
62. Woroniecki, R. P., Orlova, T. N., Mendelev, N., Shatat, I. F. et al., Urinary proteome of steroid-sensitive and steroid-resistant idiopathic nephrotic syndrome of childhood. Am. J. Nephrol. 2006, 26, 258-267.
63. Khurana, M., Traum, A. Z., Aivado, M., Wells, M. P. et al., Urine proteomic profiling of pediatric nephrotic syndrome. Pediatr. Nephrol. 2006, 21, 1257-1265.