Preparative enzymatic synthesis of polyprenyl-pyrophosphoryl-N-acetylglucosamine, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope polymers

Analytical Biochemistry

Volumn 391, Issue 2, 2009, Pages 163-165

  Al Dabbagh, Bayan ^a,b   Blanot, Didier ^a,b   Mengin Lecreulx, Dominique ^a,b   Bouhss, Ahmed ^a,b  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CELLS; CYTOLOGY;

BACTERIAL CELLS; CELL WALL POLYMERS; ENZYMATIC SYNTHESIS; INTEGRAL MEMBRANE PROTEINS; LIPOPOLYSACCHARIDES; N-ACETYLGLUCOSAMINE; POLYPRENYL PHOSPHATES; STRUCTURAL CHARACTERIZATION;

POLYMERS;

LIPID; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; N ACETYLGLUCOSAMINE; O ANTIGEN; POLYPRENYL PYROPHOSPHORYL N ACETYLGLUCOSAMINE; TRANSFERASE; UNCLASSIFIED DRUG; WECA TRANSFERASE;

ARTICLE; BACTERIAL MEMBRANE; BIOCHEMISTRY; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SYNTHESIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN STRUCTURE; THERMOTOGA MARITIMA;

BACTERIA (MICROORGANISMS);

EID: 67449132095     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.05.011     Document Type: Article

References (9)

1. Al-Dabbagh B., Mengin-Lecreulx D., and Bouhss A. Purification and characterization of the bacterial UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase WecA. J. Bacteriol. 190 (2008) 7141-7146
2. Lehrer J., Vigeant K.A., Tatar L.D., and Valvano M.A. Functional characterization and membrane topology of Escherichia coli WecA, a sugar-phosphate transferase initiating the biosynthesis of enterobacterial common antigen and O-antigen lipopolysaccharide. J. Bacteriol. 189 (2007) 2618-2628
3. Meier-Dieter U., Starman R., Barr K., Mayer H., and Rick P.D. Biosynthesis of enterobacterial common antigen in Escherichia coli: biochemical characterization of Tn10 insertion mutants defective in enterobacterial common antigen synthesis. J. Biol. Chem. 265 (1990) 13490-13497
4. Alexander D.C., and Valvano M.A. Role of the rfe gene in the biosynthesis of the Escherichia coli O7-specific lipopolysaccharide and other O-specific polysaccharides containing N-acetylglucosamine. J. Bacteriol. 176 (1994) 7079-7084
5. Mikusova K., Mikus M., Besra G.S., Hancock I., and Brennan P.J. Biosynthesis of the linkage region of the mycobacterial cell wall. J. Biol. Chem. 271 (1996) 7820-7828
6. Belanova M., Dianiskova P., Brennan P.J., Completo G.C., Rose N.L., Lowary T.L., and Mikusova K. Galactosyl transferases in mycobacterial cell wall synthesis. J. Bacteriol. 190 (2008) 1141-1145
7. McNeil M. In: Goldberg J.B. (Ed). Genetics of Bacterial Polysaccharides (1999), CRC Press, Boca Raton, FL 207-223
8. Banks K.E., Fortney K.R., Baker B., Billings S.D., Katz B.P., Munson Jr. R.S., and Spinola S.M. The enterobacterial common antigen-like gene cluster of Haemophilus ducreyi contributes to virulence in humans. J. Infect. Dis. 197 (2008) 1531-1536
9. Burda P., and Aebi M. The dolichol pathway of N-linked glycosylation. Biochim. Biophys. Acta 1426 (1999) 239-257