Ephedrine versus phenylephrine: Prevention of hypotension during spinal block for cesarean section and effects on the fetus;Efedrina versus fenilefrina: Prevenção de hipotensão arterial durante anestesia raquídea para cesariana e efeitos sobre o feto

Revista Brasileira de Anestesiologia

Volumn 59, Issue 1, 2009, Pages 11-20

  Magalhães, Edno ^a,b,c   Govêia, Catia Sousa ^a,b   De Araújo Ladeira, Luís Cláudio ^a,b   Nascimento, Bruno Góis ^b   Kluthcouski, Sérgio Murilo Cavalcante ^b  

^a HOSPITAL UNIVERSITÁRIO DE BRASÍLIA   (Brazil)

^b UNIVERSITY OF BRASILIA   (Brazil)

^c Hospital Universitário de Brasília ^*  (Brazil)

Author keywords

Anesthesia, obstetrics; Complications: hypotension; Drugs: ephedrine, phenylephrine; Surgery, obstetrics: cesarean section

Indexed keywords

ATROPINE; BUPIVACAINE; EPHEDRINE; PHENYLEPHRINE; SUFENTANIL; VASOCONSTRICTOR AGENT;

ADULT; APGAR SCORE; ARTERIAL PH; ARTICLE; BLOOD GAS ANALYSIS; BOLUS INJECTION; BRADYCARDIA; CESAREAN SECTION; CLINICAL EVALUATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FEMALE; FETUS; HUMAN; HYPOTENSION; INCIDENCE; MAJOR CLINICAL STUDY; MATERNAL TREATMENT; NAUSEA; NEWBORN; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; REACTIVE HYPERTENSION; SPINAL ANESTHESIA; UMBILICAL CORD BLOOD; VOMITING; COMPARATIVE STUDY; OBSTETRIC ANESTHESIA; PREGNANCY;

ADULT; ANESTHESIA, OBSTETRICAL; ANESTHESIA, SPINAL; CESAREAN SECTION; DOUBLE-BLIND METHOD; EPHEDRINE; FEMALE; FETUS; HUMANS; HYPOTENSION; PHENYLEPHRINE; PREGNANCY; PROSPECTIVE STUDIES; VASOCONSTRICTOR AGENTS;

EID: 67449127044     PISSN: 00347094     EISSN: 1806907X     Source Type: Journal    
DOI: 10.1590/S0034-70942009000100003     Document Type: Article

References (24)

1. Rout CC, Rocke DA - Prevention of hypotension following spinal anesthesia for cesarean section. Int Anesthesiol Clin, 1994;32:117-135.
2. Clark RB, Thompson DS, Thompson CH - Prevention of spinal hypotension associated with Cesarean section. Anesthesiology, 1976;45:670-674.
3. Hall PA, Bennett A, Wilkes MP et al. - Spinal anaesthesia for Caesarean section: comparison of infusions of phenylephrine and ephedrine. Br J Anaesth, 1994;73:471-474.
4. Kang YG, Abouleish E, Caritis S - Prophylactic intravenous ephedrine infusion during spinal anesthesia for cesarean section. Anesth Analg, 1982;61:839-842.
5. Morgan P - The role of vasopressors in the management of hypotension induced by spinal and epidural anaesthesia. Can J Anaesth, 1994;41:404-413.
6. Husaini SW, Russell IF - Volume preload: lack of effect in the prevention of spinal-induced hypotension at caesarean section. Int J Obstet Anesth, 1998;7:76-81.
7. Rout CC, Rocke DA, Levin J et al. - A reevaluation of the role of crystalloid preload in the prevention of hypotension associated with spinal anesthesia for elective cesarean section. Anesthesiology, 1993;79:262-269.
8. Ralston DH, Shnider SM, DeLorimier AA - Effects of equipotent ephedrine, metaraminol, mephentermine, and methoxamine on uterine blood flow in the pregnant ewe. Anesthesiology, 1974;40:354-370.
9. Burns SM, Cowan CM, Wilkes RG - Prevention and management of hypotension during spinal anaesthesia for elective Caesarean section: a survey of practice. Anaesthesia, 2001;56:794-798.
10. rd, Greiss FC Jr, Kemp RA - An evaluation of vasopressor therapy for maternal hypotension during spinal anesthesia. Anesthesiology, 1970;33:25-34.
11. Ratcliffe FM, Evans JM - Neonatal well-being after elective caesarean delivery with general, spinal, and epidural anaesthesia. Eur J Anaesthesiol, 1993;10:175-181.
12. Lee A, Ngan Kee WD, Gin T - A quantitative systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg, 2002;94:920-926.
13. Ngan Kee WD, Khaw KS, Ng FF et al. - Prophylactic phenylephrine infusion for the prevention of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg, 2004; 98:815-821.
14. Hawkins JL, Koonin LM, Palmer SK et al. - Anesthesia-related deaths during obstetric delivery in the United States, 1979-1990. Anesthesiology, 1997;86:277-284.
15. Roberts SW, Leveno KJ, Sidawi JE et al. - Fetal acidemia associated with regional anesthesia for elective cesarean delivery. Obstet Gynecol, 1995;85:79-83.
16. Mueller MD, Brühwiler H, Schüpfer GK et al. - Higher rate of fetal acidemia after regional anesthesia for elective cesarean delivery. Obstet Gynecol, 1997;90:131-134.
17. Jackson R, Reid JA, Thorburn J - Volume preloading is not essential to prevent spinal-induced hypotension at Caesarean section. Br J Anaesth, 1995; 75:262-265.
18. Ngan Kee WD, Khaw KS, Ng FF - Prevention of hypotension during spinal anesthesia for cesarean delivery: an effective technique using combination phenylephrine infusion and crystalloid cohydration. Anesthesiology, 2005;103:744-750.
19. Lee A, Ngan Kee WD, Gin T - A dose-response meta-analysis of prophylactic intravenous ephedrine for the prevention of hypotension during spinal anesthesia for elective cesarean delivery. Anesth Analg, 2004;98:483-490.
20. Simon L, Provenchère S, de Saint Blanquat L et al. - Dose of prophylactic intravenous ephedrine during spinal anesthesia for cesarean section. J Clin Anesth, 2001;13:366-369.
21. Ueyama H, He YL, Tanigami H et al. - Effects of crystalloid and colloid preload on blood volume in the parturient undergoing spinal anesthesia for elective cesarean section. Anesthesiology, 1999;91:1571-1576.
22. Ngan Kee WD, Khaw KS, Lee BB et al. - A dose-response study of prophylactic intravenous ephedrine for the prevention of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg, 2000;90:1390-1395.
23. Emmett RS, Cyna AM, Andrew M et al. - Techniques for preventing hypotension during spinal anaesthesia for caesarean section. Cochrane Database Syst Rev, 2002;(3):CD002251.
24. Ngan Kee WD, Lee A - Multivariate analysis of factors associated with umbilical arterial pH and standard base excess after Caesarean section under spinal anaesthesia. Anaesthesia, 2003;58:125-130.