Chikungunya and the nervous system: What we do and do not know

Reviews in Medical Virology

Volumn 19, Issue 3, 2009, Pages 121-129

  Arpino, Carla ^a   Curatolo, Paolo ^a   Rezza, Giovanni ^b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARBOVIRUS; AUTOPSY; BRAIN INFECTION; CHIKUNGUNYA ALPHAVIRUS; CHOROIDITIS; CLINICAL FEATURE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; ENCEPHALITIS; EPIDEMIC; FATALITY; HUMAN; INCIDENCE; MENINGITIS; MYELITIS; NEUROLOGIC DISEASE; NEUROTROPISM; NONHUMAN; PREVALENCE; RADICULITIS; REVIEW; SYMPTOM; VERTICAL TRANSMISSION; VIRUS CARRIER; VIRUS INFECTION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TRANSMISSION; VIRUS VIRULENCE;

ADOLESCENT; ADULT; AGED; ALPHAVIRUS INFECTIONS; ANIMALS; CHIKUNGUNYA VIRUS; CHILD; CHILD, PRESCHOOL; DISEASE MODELS, ANIMAL; HUMANS; INFANT; MALE; MIDDLE AGED; NERVOUS SYSTEM DISEASES; YOUNG ADULT;

EID: 67449123363     PISSN: 10529276     EISSN: None     Source Type: Journal    
DOI: 10.1002/rmv.606     Document Type: Review

References (47)

1. Johnson RT. Emerging viral infections of the nervous system. J Neurovirol 2003; 9: 140-147.
2. Ross RW. The Newala epidemic. III. The virus: isolation, pathogenic properties and relationship to the epidemic. J Hyg (Lond). 1956; 54: 177-191.
3. Zuckerman AJ, Banatvala JE, Pattison JR, Griffiths PD, Schaub BD. Principle and practice of Clinical Virology, 5th edn. John Wiley & Sons, Ltd: West Sussex, England; 2005.
4. Pialoux G, Gauzere B-A, Jaureguiberry S, Strobel M. Chikungunya, an epidemic arbovirosis. Lancet 2007; 7: 319-327.
5. World Health Organization.Chikungunya and dengue, south-west Indian Ocean. Wkly Epidemiol Rec 2006; 81: 105-116.
6. Charrel RN, de Lamballerie X, Raoult D. Chikungunya outbreaks - the globalization of vectorborne diseases. N Engl J Med 2007; 356: 769-771.
7. Rezza G, Nicoletti L, Angelini R, et al. Infection with Chikungunya virus in Italy: an outbreak in a temperate region. Lancet 2007; 370: 1840-1846.
8. Yergolkar PN, Tandale BV, Arankalle VA, et al. Chikungunya outbreaks caused by African genotype, India. Emerg Infect Dis 2006; 12: 1580-1583.
9. Parola P, de Lambellerie X, Jourdan J, et al. Novel Chikungunya virus variant in travelers returning from Indian Ocean islands. Emerg Infect Dis 2006; 12: 1493-1499.
10. Economopoulou A, Dominguez M, Helynck B, et al. Atypical Chikungunya virus infections: clinical manifestations, mortality and risk factors for severe disease during the 2005-2006 outbreak in Reunion. Epidemiol Infect 2008; 11:1-8 [Epub ahead of print].
11. Griffin DE. Arboviruses and the central nervous system. Springer Semin Immunopathol 1995; 17: 121-132.
12. Dropulic B, Masters CL. Entry of neurotropic arboviruses into the central nervous system: an in vitro study using mouse brain endothelium. J Infect Dis 1990; 161: 685-691.
13. Johnson KP, Johnson RT. California encephalitis. II. Studies of experimental infection in the mouse. J Neuropathol Exp Neurol 1968; 27: 390-400.
14. Johnson RT. Virus invasion of the central nervous system: a study of Sindbis virus infection in the mouse using fluorescent antibody. Am J Pathol 1965; 46: 929-943.
15. Hurwitz ES, Schell W, Nelson D, Washburn J, LaVenture M. Surveillance for California encephalitis group virus illness in Wisconsin and Minnesota, 1978. Am J Trop Med Hyg 1983; 32: 595-601.
16. Longshore WA, Stevens IM, Hollister AC, Gittelsohn A, Lennette EH. Epidemiological observations on acute infectious encephalitis in California with special reference to the 1952 outbreak. Am J Hyg 1956; 63: 69-86.
17. Earnest MP, Goolishian HA, Calverley JR, Hayes RO, Hill HR. Neurologic, intellectual and psychologic sequelae following western encephalitis: a follow-up study of 35 cases. Neurology 1971; 21: 969-974.
18. Przelomski MM, O'Rourke E, Grady GF, Berardi VP, Markley HG. Eastern equine encephalitis in Massachusetts: a report of 16 cases, 1970-1984. Neurology 1988; 38: 736-739.
19. Monath TP, Tsai TF. St. Louis encephalitis: lessons from the last decade. Am Trop Med Hyg 1987: 37 (Suppl): 40S-59S.
20. Peters CJ, Dalrymple JM. Alphaviruses. In Field's Virology, 2rd edn, Fields BN, Knipe DM (eds). Raven Press: New York, 1990.
21. Strauss JH, Strauss EG. Viruses and Human Disease, 2nd ed. Elsevier: Oxford, UK; 2008.
22. Nimmannitya S, Halstead SB, Cohen SN, Margiotta MR. Dengue and Chikungunya virus infection in man in Thailand 1962-1964. Am J Trop Med Hyg 1969; 18: 954-971.
23. Thiruvengadam KV, Kalyanasundarami V, Rajgopal JR. Clinical and pathological studies on Chikungunya fever in Madras city. India J Med Res 1965; 53: 729-744.
24. Mazaud R, Salaun JJ, Montabone H, Goube P, Bazillio R. Acute neurologic and sensorial disorders in Dengue and Chikungunya fever. Bull Soc Pathol Exot Filiales 1971; 64: 22-30.
25. Precious SW, Webb HE, Bowen ETW. Isolation and persistence of Chikungunya virus in cultures of mouse brain cells. J gen Virol 1974; 233: 271-279.
26. Robin S, Ramful D, Le Seach F, Jaffar-Bandjee MC, Rigou G, Alessandri JL. J Child Neurol 2008; 23: 1028-1035.
27. Ernould S, Walters H, Alessandri J-L, et al. Aspects pediatriques de l'epidemie de Chikungunya 2005-2006 a Saint-Denis, ile de la Réunion. Arch Pediatr 2008; 15: 253-262.
28. Rampal SM, Meena H. Neurological complications in Chikungunya fever. J Assoc Physicians India 2007; 55: 765-769.
29. Gerardin P, Barau G, Michault A, et al. Multidisciplinary prospective study of mother-to-child Chikungunya virus infections on the island of La Reunion. PLoS Med 2008; 5: e60.
30. Wielanek AC, Monredon JD, Amrani ME, Roger JC, Serveaux JP. Guillain-barrè syndrome complicating Chikungunya virus infection. Neurology 2007; 69: 2105-2107.
31. Ganesan K, Diwan A, Shankar SK, Desai SB, Sainani GS, Katrak SM. Chikungunya encephalomyeloradiculitis: report of 2 cases with neuroimaging and 1 case with autopsy findings. AJNR Am J Neuroradihl 2008; 29: 1626-1637.
32. Singhi SS, Manimunda SP, Suganan AP, Sahina, Vijayachari P. Four cases of acute flaccid paralysis associated with Chikungunya virus infection. Epidemiol Infect 2008; 136: 1277-1280.
33. Ramful D, Carbonnier M, Pasquet M, et al. Mother-to-child transmission of Chikungunya virus infection. Pediatr Infect Dis J 2007; 26: 811-815.
34. Sissoko D, Malvy D, Giry C, et al. Outbreak of Chikungunya fever in Mayotte, Comoros archipelago, 2005-2006. Trans R Soc Trop Med Hyg 2008; 102: 780-786.
35. Griffin DE. Neuronal cell death in Alphavirus encephalomyelitis. Curr Top Microbiol Immunol 2005; 289: 57-77.
36. Couderc T, Chretien F, Schilte C, et al. A mouse model for Chikungunya: young age and inefficient type-I interferon signalling are risk factors for severe disease. PLoS Pathog 2008; 4 (2): e29.
37. Fazakerley JK, Cotterill CL, Lee G, Graham A. Virus tropism, distribution, persistence and pathology in the corpus callosum of the Semliki Forest virus-infected mouse brain: a novel system to study virus-oligodendrocyte interactions. Neuropathol Appl Neurobiol 2006; 32: 397-409.
38. Chatterjee SN, Sarkar JK. Electron miscroscopy studies of suckling mouse brain cells infected with Chikungunya virus. Indian J Exp Biol 1965; 3: 227-234.
39. White JD. Electron microscopy of Chikungunya virus infection in the nervous system of suckling mice. Defense Technical Information Centre: Fort Detrick, MD; 1969.
40. Grivard P, Le Roux K, Laurent P, et al. Molecular and serological diagnostic of Chikungunya virus infection. Pathol Biol 2007; 55: 490-494.
41. Soilu-Hanninen M, Eralinna JP, Hukkanen V, et al. Semliki Forest virus infects mouse brain endothelial cells and causes blood brain barrier damage. J Virol 1994; 68: 6291-6298.
42. Pathak S, Webb HE. Possible mechanisms for the transport of Semliki Forest virus into and within mouse brain. An electron microscopic study. J Neurol Sci 1974; 23: 175-184.
43. Ali M, Safriel Y, Sohi J, et al. West Nile virus infection: MR imaging findings in the nervous system. AJNR Am J Neuroradiol 2005; 26: 289-297.
44. Smithburn KC, Hughes TP, Burke AW, Paul JH. A neurotropic virus isolated from the blood of a native of Uganda. Am J Trop Med Hyg 1940; 20: 471-492.
45. Southam CM, Moore AE. Induced virus infections in man by the Egypt isolates of West Nile virus. Am J Trop Med Hyg 1954; 3: 19-50.
46. Johnson TR. Viral infections of the nervous system, 2nd edn. Lippincott-Raven: Philadelphia, PA; 1998.
47. Casolari S, Briganti E, Zanotti M, et al. A fatal case of encephalitis associated with Chikungunya virus infection. Scand J Infect Dis 2008; 40: 995-996.