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Volumn 5, Issue , 2009, Pages 475-481

Improving outcomes in patients undergoing percutaneous coronary intervention: Role of prasugrel

Author keywords

Dual oral antiplatelet therapy; Oral thienopyridine; P2Y12 receptors; Prasugrel

Indexed keywords

CANGRELOR; CLOPIDOGREL; PRASUGREL; PURINERGIC P2Y12 RECEPTOR; THIENOPYRIDINE DERIVATIVE; THIOLACTONE; TICAGRELOR; TICLOPIDINE; ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; DRUG DERIVATIVE; PIPERAZINE DERIVATIVE; THIOPHENE DERIVATIVE;

EID: 67449097605     PISSN: 11766344     EISSN: 11782048     Source Type: Journal    
DOI: 10.2147/vhrm.s3969     Document Type: Review
Times cited : (4)

References (58)
  • 1
    • 0030033339 scopus 로고    scopus 로고
    • Prospective evaluation of hemostatic predictors of subacute stent thrombosis after coronary Palmaz-Schatz stenting
    • Neumann FJ, Gawaz M, Ott I, May A, Mössmer G, Schömig A. Prospective evaluation of hemostatic predictors of subacute stent thrombosis after coronary Palmaz-Schatz stenting. J Am Coll Cardiol. 1996;27:15-21.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 15-21
    • Neumann, F.J.1    Gawaz, M.2    Ott, I.3    May, A.4    Mössmer, G.5    Schömig, A.6
  • 2
    • 0032189692 scopus 로고    scopus 로고
    • Effects of clopidogrel, aspirin and combined therapy in a porcine ex vivo model of high-shear induced stent thrombosis
    • Makkar RR, Eigler S, Kaul S, et al. Effects of clopidogrel, aspirin and combined therapy in a porcine ex vivo model of high-shear induced stent thrombosis. Eur Heart J. 1998;19:1538-1546.
    • (1998) Eur Heart J , vol.19 , pp. 1538-1546
    • Makkar, R.R.1    Eigler, S.2    Kaul, S.3
  • 3
    • 84995360022 scopus 로고    scopus 로고
    • European Society of Cardiology. Management and outcome of patients with established coronary artery disease: The Euro Heart Survey on coronary revascularization
    • Lenzen MJ, Boersma E, Bertrand ME, et al; European Society of Cardiology. Management and outcome of patients with established coronary artery disease: the Euro Heart Survey on coronary revascularization. Eur Heart J. 2005;26(12):1169-1179.
    • (2005) Eur Heart J , vol.26 , Issue.12 , pp. 1169-1179
    • Lenzen, M.J.1    Boersma, E.2    Bertrand, M.E.3
  • 4
    • 33644849222 scopus 로고    scopus 로고
    • American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics - 2006 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Thom T, Haase N, Rosamond W, et al; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics - 2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2006;113(6):e85-e101.
    • (2006) Circulation , vol.113 , Issue.6
    • Thom, T.1    Haase, N.2    Rosamond, W.3
  • 5
    • 0033678468 scopus 로고    scopus 로고
    • Identification and biological activity of the active metabolite of clopidogrel
    • Savi P, Pereillo JM, Uzabiaga MF, et al. Identification and biological activity of the active metabolite of clopidogrel. Thromb Haemost. 2000;84:891-896.
    • (2000) Thromb Haemost , vol.84 , pp. 891-896
    • Savi, P.1    Pereillo, J.M.2    Uzabiaga, M.F.3
  • 6
    • 33749510291 scopus 로고    scopus 로고
    • Pharmacology of thienopyridines: Rationale for dual pathway inhibition
    • Ibanez B, Vilahur G, Badimon JJ, Pharmacology of thienopyridines: rationale for dual pathway inhibition. Eur Heart J Suppl. 2006;8:G3-G9.
    • (2006) Eur Heart J Suppl , vol.8
    • Ibanez, B.1    Vilahur, G.2    Badimon, J.J.3
  • 7
    • 0034622539 scopus 로고    scopus 로고
    • Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting: The Clopidogrel Aspirin Stent International Cooperative Study (CLASSICS)
    • Bertrand ME, Rupprecht HJ, Urban P, Gershlick AH. Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting: the Clopidogrel Aspirin Stent International Cooperative Study (CLASSICS). Circulation. 2000;102:624-629.
    • (2000) Circulation , vol.102 , pp. 624-629
    • Bertrand, M.E.1    Rupprecht, H.J.2    Urban, P.3    Gershlick, A.H.4
  • 8
    • 0037005777 scopus 로고    scopus 로고
    • Meta-analysis of randomized and registry comparisons of ticlopidine and clopidogrel after stenting
    • Bhatt DL, Bertrand ME, Berger PB, et al. Meta-analysis of randomized and registry comparisons of ticlopidine and clopidogrel after stenting. J Am Coll Cardiol. 2002;39:9-14.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 9-14
    • Bhatt, D.L.1    Bertrand, M.E.2    Berger, P.B.3
  • 9
    • 20244377701 scopus 로고    scopus 로고
    • Guidelines for percutaneous coronary interventions. The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology
    • for Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology
    • Silber S, Albertsson P, Aviles FF, et al; for Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology. Guidelines for percutaneous coronary interventions. The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology. Eur Heart J. 2005;26(8):804-847.
    • (2005) Eur Heart J , vol.26 , Issue.8 , pp. 804-847
    • Silber, S.1    Albertsson, P.2    Aviles, F.F.3
  • 10
    • 33947718387 scopus 로고    scopus 로고
    • Role of clopidogrel in managing atherothrombotic cardiovascular disease
    • Eshaghian S, Kaul S, Amin S, Shah PK, Diamond GA. Role of clopidogrel in managing atherothrombotic cardiovascular disease. Ann Intern Med. 2007;146(6):434-441.
    • (2007) Ann Intern Med , vol.146 , Issue.6 , pp. 434-441
    • Eshaghian, S.1    Kaul, S.2    Amin, S.3    Shah, P.K.4    Diamond, G.A.5
  • 11
    • 1542722301 scopus 로고    scopus 로고
    • Effect of clopidogrel pretreatment on inflammatory marker expression in patients undergoing percutaneous coronary intervention
    • Quinn MJ, Bhatt DL, Zidar F, et al. Effect of clopidogrel pretreatment on inflammatory marker expression in patients undergoing percutaneous coronary intervention. Am J Cardiol. 2004;93:679-684.
    • (2004) Am J Cardiol , vol.93 , pp. 679-684
    • Quinn, M.J.1    Bhatt, D.L.2    Zidar, F.3
  • 12
    • 3242693541 scopus 로고    scopus 로고
    • Effect of clopidogrel pretreatment on periprocedural rise in C-reactive protein after percutaneous coronary intervention
    • Vivekananthan DP, Bhatt DL, Chew DP, et al. Effect of clopidogrel pretreatment on periprocedural rise in C-reactive protein after percutaneous coronary intervention. Am J Cardiol. 2004;94:358-360.
    • (2004) Am J Cardiol , vol.94 , pp. 358-360
    • Vivekananthan, D.P.1    Bhatt, D.L.2    Chew, D.P.3
  • 13
    • 18644372477 scopus 로고    scopus 로고
    • Structure and stereochemistry of the active metabolite of clopidogrel
    • Pereillo JM, Maftouh M, Andrieu A, et al. Structure and stereochemistry of the active metabolite of clopidogrel. Drug Metab Dispos. 2002;30:1288-1295.
    • (2002) Drug Metab Dispos , vol.30 , pp. 1288-1295
    • Pereillo, J.M.1    Maftouh, M.2    Andrieu, A.3
  • 14
    • 0038508970 scopus 로고    scopus 로고
    • The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin
    • Clarke TA, Waskell LA. The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin. Drug Metab Dispos. 2003;31:53-59.
    • (2003) Drug Metab Dispos , vol.31 , pp. 53-59
    • Clarke, T.A.1    Waskell, L.A.2
  • 15
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • Gurbel PA, Bliden KP, Hiatt BL, O'Connor CM. Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation. 2003;107:2908-2913.
    • (2003) Circulation , vol.107 , pp. 2908-2913
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3    O'Connor, C.M.4
  • 17
    • 37849002889 scopus 로고    scopus 로고
    • 12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
    • 12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease. Eur Heart J. 2008;29:21-30.
    • (2008) Eur Heart J , vol.29 , pp. 21-30
    • Wallentin, L.1    Varenhorst, C.2    James, S.3
  • 19
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med. 2009;360:363-375.
    • (2009) N Engl J Med , vol.360 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 20
    • 67650901939 scopus 로고    scopus 로고
    • Motovska Z, Widimsky P, Petr R, et al. on behalf of the PRAGUE-8 Study Investigators. Factors influencing clopidogrel efficacy in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention: statin's advantage and the smoking paradox. J Cardiovasc Pharmacol. 2009 Feb 25. [Epub ahead of print].
    • Motovska Z, Widimsky P, Petr R, et al. on behalf of the PRAGUE-8 Study Investigators. Factors influencing clopidogrel efficacy in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention: statin's advantage and the smoking "paradox". J Cardiovasc Pharmacol. 2009 Feb 25. [Epub ahead of print].
  • 21
    • 74049116884 scopus 로고    scopus 로고
    • Optimal pretreatment timing for high load dosing (600 mg) of clopidogrel before planned percutaneous coronary intervention for maximal antiplatelet effectiveness
    • Feb 14, Epub ahead of print
    • Motovska Z, Widimsky P, Petr R, et al. Optimal pretreatment timing for high load dosing (600 mg) of clopidogrel before planned percutaneous coronary intervention for maximal antiplatelet effectiveness. Int J Cardiol. 2009 Feb 14. [Epub ahead of print].
    • (2009) Int J Cardiol
    • Motovska, Z.1    Widimsky, P.2    Petr, R.3
  • 22
    • 0030754003 scopus 로고    scopus 로고
    • Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease
    • Davì G, Gresele P, Violi F, et al. Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease. Circulation. 1997;96(1):69-75.
    • (1997) Circulation , vol.96 , Issue.1 , pp. 69-75
    • Davì, G.1    Gresele, P.2    Violi, F.3
  • 23
    • 0038300483 scopus 로고    scopus 로고
    • Impact of angina class on inhibition of platelet aggregation following clopidogrel loading in patients undergoing coronary intervention: Do we need more aggressive dosing regimens in unstable angina?
    • Soffer D, Moussa I, Harjai K, et al. Impact of angina class on inhibition of platelet aggregation following clopidogrel loading in patients undergoing coronary intervention: do we need more aggressive dosing regimens in unstable angina? Catheter Cardiovasc Interv. 2003;59:21-25.
    • (2003) Catheter Cardiovasc Interv , vol.59 , pp. 21-25
    • Soffer, D.1    Moussa, I.2    Harjai, K.3
  • 24
    • 33747874088 scopus 로고    scopus 로고
    • A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: The ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial
    • for the ALBION Trial Investigators
    • Montalescot G, Sideris G, Meuleman C, et al; for the ALBION Trial Investigators. A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial. J Am Coll Cardiol. 2006;48:931-938.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 931-938
    • Montalescot, G.1    Sideris, G.2    Meuleman, C.3
  • 25
    • 33749503499 scopus 로고    scopus 로고
    • Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation
    • Geisler T, Langer H, Wydymus M, et al. Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation. Eur Heart J. 2006;27(20):2420-2425.
    • (2006) Eur Heart J , vol.27 , Issue.20 , pp. 2420-2425
    • Geisler, T.1    Langer, H.2    Wydymus, M.3
  • 26
    • 34948875324 scopus 로고    scopus 로고
    • Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease
    • Angiolillo DJ, Bernardo E, Sabate M, et al. Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease J Am Coll Cardiol. 2007;50:1541-1547.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1541-1547
    • Angiolillo, D.J.1    Bernardo, E.2    Sabate, M.3
  • 27
    • 27744516843 scopus 로고    scopus 로고
    • Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: Results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Effect) Trial
    • von Beckerath N, Taubert D, Pogatsa-Murray G, Schomig E, Kastrati A, Schomig A. Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: Results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Effect) Trial. Circulation. 2005;112(19):2946-2950.
    • (2005) Circulation , vol.112 , Issue.19 , pp. 2946-2950
    • von Beckerath, N.1    Taubert, D.2    Pogatsa-Murray, G.3    Schomig, E.4    Kastrati, A.5    Schomig, A.6
  • 28
    • 34250020766 scopus 로고    scopus 로고
    • Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis
    • Buonamici P, Marcucci R, Migliorini A, et al. Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis. J Am Coll Cardiol. 2007;49(24):2312-2317.
    • (2007) J Am Coll Cardiol , vol.49 , Issue.24 , pp. 2312-2317
    • Buonamici, P.1    Marcucci, R.2    Migliorini, A.3
  • 29
    • 34249053105 scopus 로고    scopus 로고
    • The disposition of prasugrel, a novel thienopyridine, in humans
    • Farid NA, Smith RL, Gillespie TA, et al. The disposition of prasugrel, a novel thienopyridine, in humans. Drug Metab Dispos. 2007;35:1096-1104.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1096-1104
    • Farid, N.A.1    Smith, R.L.2    Gillespie, T.A.3
  • 31
    • 33845451677 scopus 로고    scopus 로고
    • A comparison of prasugrel and clopidogrel loading doses on platelet function: Magnitude of platelet inhibition is related to active metabolite formation
    • Brandt JT, Payne CD, Wiviott SD, et al. A comparison of prasugrel and clopidogrel loading doses on platelet function: Magnitude of platelet inhibition is related to active metabolite formation. Am Heart J. 2007;153:e9-e16.
    • (2007) Am Heart J , vol.153
    • Brandt, J.T.1    Payne, C.D.2    Wiviott, S.D.3
  • 32
    • 37349111065 scopus 로고    scopus 로고
    • Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: The Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial
    • Wiviott SD, Trenk D, Frelinger AL, et al. Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. Circulation. 2007;116:2923-2932.
    • (2007) Circulation , vol.116 , pp. 2923-2932
    • Wiviott, S.D.1    Trenk, D.2    Frelinger, A.L.3
  • 33
    • 34250714831 scopus 로고    scopus 로고
    • The greater in vivo anti-platelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite
    • Sugidachi A, Ogawa T, Kurihara A, et al. The greater in vivo anti-platelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost. 2007;5:1545-1551.
    • (2007) J Thromb Haemost , vol.5 , pp. 1545-1551
    • Sugidachi, A.1    Ogawa, T.2    Kurihara, A.3
  • 34
    • 0038291914 scopus 로고    scopus 로고
    • Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement
    • Muller I, Besta F, Schulz C, Massberg S, Schomig A, Gawaz M. Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement. Thromb Haemost. 2003;89:783-787.
    • (2003) Thromb Haemost , vol.89 , pp. 783-787
    • Muller, I.1    Besta, F.2    Schulz, C.3    Massberg, S.4    Schomig, A.5    Gawaz, M.6
  • 35
    • 29344466941 scopus 로고    scopus 로고
    • Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: The role of dual drug resistance
    • Lev EI, Patel RT, Maresh KJ, et al. Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance. J Am Coll Cardiol. 2006;47(1):27-33.
    • (2006) J Am Coll Cardiol , vol.47 , Issue.1 , pp. 27-33
    • Lev, E.I.1    Patel, R.T.2    Maresh, K.J.3
  • 36
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Matetzky S, Shenkman B, Guetta V, et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation. 2004;109:3171-3175.
    • (2004) Circulation , vol.109 , pp. 3171-3175
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3
  • 37
    • 33646732608 scopus 로고    scopus 로고
    • Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease
    • Jernberg T, Payne CD, Winters KJ, et al. Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease. Eur Heart J. 2006;27:1166-1173.
    • (2006) Eur Heart J , vol.27 , pp. 1166-1173
    • Jernberg, T.1    Payne, C.D.2    Winters, K.J.3
  • 38
    • 61649096199 scopus 로고    scopus 로고
    • Benefits and risks of clopidogrel use in patients with coronary artery disease: Evidence from randomized studies and registries
    • 30P2:2191-2202
    • Motovska Z, Kala P. Benefits and risks of clopidogrel use in patients with coronary artery disease: Evidence from randomized studies and registries. Clin Ther. 2008;30P2:2191-2202.
    • (2008) Clin Ther
    • Motovska, Z.1    Kala, P.2
  • 39
    • 36148983750 scopus 로고    scopus 로고
    • TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH, et al; TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Eng J Med. 2007;357:2001-2015.
    • (2007) N Eng J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 40
    • 60649112469 scopus 로고    scopus 로고
    • TRITON-TIMI 38 investigators. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): Double-blind, randomised controlled trial
    • Montalescot G, Wiviott SD, Braunwald E, Murphy SA, Gibson CM, McCabe CH, Antman EM; TRITON-TIMI 38 investigators. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial. Lancet. 2009;373(9665):723-731.
    • (2009) Lancet , vol.373 , Issue.9665 , pp. 723-731
    • Montalescot, G.1    Wiviott, S.D.2    Braunwald, E.3    Murphy, S.A.4    Gibson, C.M.5    McCabe, C.H.6    Antman, E.M.7
  • 42
    • 20844445776 scopus 로고    scopus 로고
    • Stent thrombosis following bare-metal stent implantation success of emergency percutaneous coronary intervention and predictors of adverse outcome
    • Wenaweser P, Rey C, Eberli F, et al. Stent thrombosis following bare-metal stent implantation success of emergency percutaneous coronary intervention and predictors of adverse outcome. Eur Heart J. 2005;26(12):1180-1187.
    • (2005) Eur Heart J , vol.26 , Issue.12 , pp. 1180-1187
    • Wenaweser, P.1    Rey, C.2    Eberli, F.3
  • 43
    • 61549132559 scopus 로고    scopus 로고
    • Early stent thrombosis: Past, present, and future
    • Cook S, Windecker S. Early stent thrombosis: Past, present, and future. Circulation. 2009;119:657-659.
    • (2009) Circulation , vol.119 , pp. 657-659
    • Cook, S.1    Windecker, S.2
  • 44
    • 17844373254 scopus 로고    scopus 로고
    • Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents
    • Iakovou I, Schmidt T, Bonizzoni E, et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA. 2005;293:2126-2130.
    • (2005) JAMA , vol.293 , pp. 2126-2130
    • Iakovou, I.1    Schmidt, T.2    Bonizzoni, E.3
  • 45
    • 42149119040 scopus 로고    scopus 로고
    • Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: A sub-analysis of a randomised trial
    • Wiviott SD, Braunwald E, McCabe CH, et al. Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a sub-analysis of a randomised trial. Lancet. 2008;371(9621):1353-1363.
    • (2008) Lancet , vol.371 , Issue.9621 , pp. 1353-1363
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 46
    • 55949103494 scopus 로고    scopus 로고
    • TRITON-TIMI 38 Investigators. Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel - Thrombolysis in Myocardial Infarction 38
    • Wiviott SD, Braunwald E, Angiolillo DJ, et al; TRITON-TIMI 38 Investigators. Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel - Thrombolysis in Myocardial Infarction 38. Circulation. 2008;118(16):1626-1636.
    • (2008) Circulation , vol.118 , Issue.16 , pp. 1626-1636
    • Wiviott, S.D.1    Braunwald, E.2    Angiolillo, D.J.3
  • 47
    • 34547906405 scopus 로고    scopus 로고
    • Diabetes and mortality following acute coronary syndromes
    • Donahoe SM, Stewart GC, McCabe CH, et al. Diabetes and mortality following acute coronary syndromes. JAMA. 2007;298:765-775.
    • (2007) JAMA , vol.298 , pp. 765-775
    • Donahoe, S.M.1    Stewart, G.C.2    McCabe, C.H.3
  • 48
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345:494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 49
    • 33847130538 scopus 로고    scopus 로고
    • Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease: Results of the optimizing anti-platelet therapy in diabetes mellitus (OPTIMUS) study
    • Angiolillo DJ, Showmaker SB, Desai B, et al. Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease: results of the optimizing anti-platelet therapy in diabetes mellitus (OPTIMUS) study. Circulation. 2007;115(6):708-716.
    • (2007) Circulation , vol.115 , Issue.6 , pp. 708-716
    • Angiolillo, D.J.1    Showmaker, S.B.2    Desai, B.3
  • 50
    • 34948875324 scopus 로고    scopus 로고
    • Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease
    • Angiolillo DJ, Bernardo E, Sabate M, et al. Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease J Am Coll Cardiol. 2007;50:1541-1547.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1541-1547
    • Angiolillo, D.J.1    Bernardo, E.2    Sabate, M.3
  • 51
    • 56849130022 scopus 로고    scopus 로고
    • Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo
    • Erlinge D, Varenhorst C, Braun OÖ, et al. Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo. J Am Coll Cardiol. 2008;52:1968-1977.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1968-1977
    • Erlinge, D.1    Varenhorst, C.2    Braun, O.O.D.I.E.3
  • 52
    • 55949103494 scopus 로고    scopus 로고
    • Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in TRITON-TIMI 38
    • Wiviott SD, Braunwald E, Angiolillo DJ, et al. Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in TRITON-TIMI 38. Circulation. 2008;118:1626-1636.
    • (2008) Circulation , vol.118 , pp. 1626-1636
    • Wiviott, S.D.1    Braunwald, E.2    Angiolillo, D.J.3
  • 53
    • 67649522036 scopus 로고    scopus 로고
    • Motovska Z, Widimsky P, Kvasnicka J, et al; on behalf of the PRAGUE-8 study investigators. High loading dose of clopidogrel is unable to satisfactorily inhibit platelet reactivity in patients with glycoprotein IIIA gene polymorphism - a genetic substudy of PRAGUE-8 trial. Blood Coagul Fibrin. 2009. March 16; doi:10.1097/ MBC.0b013e328325455b.
    • Motovska Z, Widimsky P, Kvasnicka J, et al; on behalf of the PRAGUE-8 study investigators. High loading dose of clopidogrel is unable to satisfactorily inhibit platelet reactivity in patients with glycoprotein IIIA gene polymorphism - a genetic substudy of PRAGUE-8 trial. Blood Coagul Fibrin. 2009. March 16; doi:10.1097/ MBC.0b013e328325455b.
  • 54
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med. 2009;360:363-375.
    • (2009) N Engl J Med , vol.360 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 55
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome P-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome P-450 polymorphisms and response to clopidogrel. N Engl J Med. 2009;360:354-362.
    • (2009) N Engl J Med , vol.360 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 56
    • 36348943475 scopus 로고    scopus 로고
    • Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
    • Brandt JT, Close SL, Iturria SJ, et al. Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel. J Thromb Haemost. 2007;5:2429-2436.
    • (2007) J Thromb Haemost , vol.5 , pp. 2429-2436
    • Brandt, J.T.1    Close, S.L.2    Iturria, S.J.3


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