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Volumn 15, Issue 2, 2009, Pages 88-89

Severe hepatotoxicity in a patient on bosentan upon addition of methotrexate: Reversible with resumption of methotrexate without bosentan

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; BOSENTAN; FISH OIL; FOLIC ACID; METHOTREXATE; MULTIVITAMIN; OMEPRAZOLE; PREDNISOLONE; SILDENAFIL; ANTIHYPERTENSIVE AGENT; DERMATOLOGICAL AGENT; SULFONAMIDE;

EID: 67449085320     PISSN: 10761608     EISSN: None     Source Type: Journal    
DOI: 10.1097/RHU.0b013e31819bc71f     Document Type: Article
Times cited : (11)

References (9)
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    • (2007) Ann Rheum Dis , vol.66 , pp. 940-944
    • Steen, V.D.1    Medsger Jr., T.A.2
  • 2
    • 0030705165 scopus 로고    scopus 로고
    • Methotrexate hepatotoxicity
    • West SG. Methotrexate hepatotoxicity. Rheum Dis Clin North Am. 1997;23: 883-915.
    • (1997) Rheum Dis Clin North Am , vol.23 , pp. 883-915
    • West, S.G.1
  • 3
    • 32644469104 scopus 로고    scopus 로고
    • Drug-related hepatotoxicity
    • Navarro VJ, Senior JR. Drug-related hepatotoxicity. N Engl J Med. 2006;354: 731-739.
    • (2006) N Engl J Med , vol.354 , pp. 731-739
    • Navarro, V.J.1    Senior, J.R.2
  • 4
    • 0032995719 scopus 로고    scopus 로고
    • Absorption, excretion and metabolism of the endothelin receptor antagonist bosentan in healthy male subjects
    • Weber C, Gasser R, Hopfgartner G. Absorption, excretion and metabolism of the endothelin receptor antagonist bosentan in healthy male subjects. Drug Metab Dispos. 1999;27:810-815.
    • (1999) Drug Metab Dispos , vol.27 , pp. 810-815
    • Weber, C.1    Gasser, R.2    Hopfgartner, G.3
  • 5
    • 10944231356 scopus 로고    scopus 로고
    • Clinical pharmacology of bosentan, a dual endothelin receptor antagonist
    • Dingemanse J, Van Giersbergen PL. Clinical pharmacology of bosentan, a dual endothelin receptor antagonist. Clin Pharmacokinet. 2004;43:1089-1115.
    • (2004) Clin Pharmacokinet , vol.43 , pp. 1089-1115
    • Dingemanse, J.1    Van Giersbergen, P.L.2
  • 6
    • 1842425908 scopus 로고    scopus 로고
    • Bioavailability of higher dose MTX comparing oral and subcutaneous administration in patients with rheumatoid arthritis
    • Hoekstra M, Haagsma C, Neef C, et al. Bioavailability of higher dose MTX comparing oral and subcutaneous administration in patients with rheumatoid arthritis. J Rheumatol. 2004;31:645-648.
    • (2004) J Rheumatol , vol.31 , pp. 645-648
    • Hoekstra, M.1    Haagsma, C.2    Neef, C.3
  • 7
    • 0029898079 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis
    • Bannwarth B, Pehourcq F, Schaeverkbeke T, et al. Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis. Clin Pharmacokinet. 1996;30:194-210.
    • (1996) Clin Pharmacokinet , vol.30 , pp. 194-210
    • Bannwarth, B.1    Pehourcq, F.2    Schaeverkbeke, T.3
  • 8
    • 33646256150 scopus 로고    scopus 로고
    • Bosentan may induce arthritis flare in patients with scleroderma concomitantly treated with methotrexate
    • Cozzi F, Ostuni PA, Marotta H, et al. Bosentan may induce arthritis flare in patients with scleroderma concomitantly treated with methotrexate. Ann Rheum Dis. 2006;65:692-693.
    • (2006) Ann Rheum Dis , vol.65 , pp. 692-693
    • Cozzi, F.1    Ostuni, P.A.2    Marotta, H.3
  • 9
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    • Pharmacokinetics of low-dose methotrexate in rheumatoid arthritis patients
    • Herman RA, Veng-Pedersen P, Hoffman J, et al. Pharmacokinetics of low-dose methotrexate in rheumatoid arthritis patients. J Pharm Sci. 1989;78:165-171.
    • (1989) J Pharm Sci , vol.78 , pp. 165-171
    • Herman, R.A.1    Veng-Pedersen, P.2    Hoffman, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.