Reduced lung lesions in pigs challenged 25 weeks after the administration of a single dose of Mycoplasma hyopneumoniae vaccine at approximately 1 week of age

Veterinary Journal

Volumn 181, Issue 3, 2009, Pages 312-320

  Reynolds, S C ^a   St Aubin, L B ^b   Sabbadini, L G ^b   Kula, J ^c   Vogelaar, J ^d   Runnels, P ^b   Peters, A R ^e  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^b PFIZER INC   (United States)

^c Assured Research Services Inc   (United States)

^d Barton's West End Facilities   (United States)

^e Arpexas Ltd   (United Kingdom)

Author keywords

Duration of immunity; Lung lesion; Maternal antibody; Mycoplasma hyopneumoniae; Pig; Vaccine

Indexed keywords

BACTERIAL VACCINE; MYCOPLASMA HYOPNEUMONIAE VACCINE; PLACEBO; STELLAMUNE ONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY DETECTION; ANTIBODY RESPONSE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; LUNG LESION; MYCOPLASMA HYOPNEUMONIAE; MYCOPLASMAL PNEUMONIA OF SWINE; NONHUMAN; SEROLOGY; SINGLE DRUG DOSE;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL VACCINES; FEMALE; LUNG; MALE; MYCOPLASMA HYOPNEUMONIAE; PNEUMONIA OF SWINE, MYCOPLASMAL; SWINE;

MYCOPLASMA HYOPNEUMONIAE; SUIDAE;

EID: 67349277685     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2008.03.012     Document Type: Article

References (33)

1. 9 CFR, 1999a. Part 1-4. Animal Welfare. Code of Federal Regulations. US Government Printing Office, Washington, DC, pp. 7-115.
2. 9 CFR, 1999b. Part 103. Experimental Production, Distribution, and Evaluation of Biological Products Prior to Licensing. Code of Federal Regulations. US Government Printing Office, Washington, DC, pp. 513-514.
3. Bereiter M., Young T.F., Joo H.S., and Ross R.F. Evaluation of the ELISA and comparison to the complement fixation test and radial immunodiffusion enzyme assay for detection of antibodies against Mycoplasma hyopneumoniae in swine serum. Veterinary Microbiology 25 (1990) 177-192
4. Buddle J.R., and O'Hara A.J. Enzootic pneumonia of pigs - a diagnostic dilemma. Australian Veterinary Journal 83 (2005) 134-139
5. Charlier, P., Chiers, K., Maes, D., 2000. Comparative efficacy of Stellamune™ Mycoplasma and Hyoresp in pigs against an experimental challenge with M. hyopneumoniae. In: Proceedings of the 16th International Pig Veterinary Society Congress, Melbourne, Australia, pp. 501.
6. Dawson A., Thevasagayam S.J., Sherington J., MacKinnon J.D., Stipkovits L.P., and Peters A.R. The duration of immunity after vaccination with a single dose Mycoplasma hyopneumoniae vaccine and the effect of serological status on lung lesion scores. The Pig Journal 50 (2002) 83-92
7. Djordjevic S.P., Eamens G.J., Romalis L.F., Nicholls P.J., Taylor V., and Chin J. Serum and mucosal antibody responses and protection in pigs vaccinated against Mycoplasma hyopneumoniae with vaccines containing a denatured membrane antigen pool and adjuvant. Australian Veterinary Journal 75 (1997) 504-511
8. Feenstra, A.A., Sørensen, V., Frijs, N.F., Jensen, N.E., Bille-Hansen, V., 1994. Experimental M. hyopneumoniae infection in pigs. Clinical signs, lesions and microbiology. In: Proceedings of the 13th International Pig Veterinary Society Congress, Bangkok, Thailand, pp. 187.
9. Haesebrouck F., Pasmans F., Chiers K., Maes D., Ducatelle R., and Decostere A. Efficacy of vaccines against bacterial diseases in swine: what can we expect?. Veterinary Microbiology 100 (2004) 255-268
10. Hodgins D.C., Shewen P.E., and Dewey C.E. Influence of age and maternal antibodies on antibody responses of neonatal piglets vaccinated against Mycoplasma hyopneumoniae. Journal of Swine Health and Production 12 (2004) 10-16
11. ® One (Pfizer GmbH) relevant to the use of the vaccine in veterinary practice. Tieräerztliche Umschau 61 (2006) 316-321 (in German)
12. Hsu T., and Minion F.C. Identification of the cilium binding epitope of the Mycoplasma hyopneumoniae P97 adhesin. Infection and Immunity 66 (1998) 4762-4766
13. Kwon D., Choi C., and Chae C. Chronologic localization of Mycoplasma hyopneumoniae in experimentally infected pigs. Veterinary Pathology 39 (2002) 584-587
14. Maes D., Verdonck M., Deluyker H., and de Kruif A. Enzootic pneumonia in pigs. Veterinary Quarterly 18 (1996) 104-109
15. Martelli P., Terreni M., Guazzetti S., and Cavirani S.M. Antibody response to Mycoplasma hyopneumoniae infection in vaccinated pigs with or without maternal antibodies induced by sow vaccination. Journal of Veterinary Medicine Series B 53 (2006) 229-233
16. Minion F.C. Molecular pathogenesis of mycoplasma animal respiratory pathogens. Frontiers in Bioscience 7 (2002) 1410-1422
17. Pallarés F.J., Gómez S., Ramis G., Seva J., and Muñoz A. Vaccination against swine enzootic pneumonia in field conditions: effect on clinical, pathological, zootechnical and economic parameters. Veterinary Research 31 (2000) 573-582
18. Pallarés F.J., Gómez S., and Muñoz A. Evaluation of the zootechnical parameters of vaccinating against swine enzootic pneumonia under field conditions. Veterinary Record 148 (2001) 104-107
19. Pointon A.M., Mercy A.R., Backstrom L., and Dial G.D. Disease surveillance at slaughter. In: Leman A.D., Straw B.E., Mengeling W.L., et al. (Eds). Diseases of Swine. 7th ed. (1992), ISU Press, Ames, IA 968-987
20. ®, administered to pigs at approximately one week of age, reduces lung lesions consistent with M. hyopneumoniae from as early as 2 weeks post vaccination. In: Proceedings of the 19th International Pig Veterinary Society Congress, Copenhagen, Denmark, pp. 230.
21. Ross R.F., Zimmermann-Erickson B.J., and Young T.F. Characteristics of protective activity of Mycoplasma hyopneumoniae vaccine. American Journal of Veterinary Research 45 (1984) 1899-1905
22. Smith, S.C., Kolodziejczyk, P., Lesiak, M., Leśniewski, S., Salt, J.S., Żmudzki, J., 2003a. The efficacy of a single dose vaccine for pigs RespiSure One™ against Mycoplasma hyopneumoniae. Życie Weterynaryjine 78, 641-646 (in Polish).
23. ® mono injection against enzootic pneumonia in pigs under field conditions. Revue de Médecine Vétérinaire 154 (2003) 679-687 (in French)
24. ® One, a single dose Mycoplasma hyopneumoniae vaccine, administered in pigs at one week of age under field conditions. Tierärztliche Umschau 6 (2003) 316-324 (in German)
25. Straw B.E., Shin S.J., and Yeager A.E. Effect of pneumonia on growth rate and feed efficiency of minimal disease pigs exposed to Actinobacillus pleuropneumoniae and Mycoplasma hyopneumoniae. Preventive Veterinary Medicine 9 (1990) 287-294
26. Thacker E.L., Thacker B.J., Boettcher T.B., and Jayappa H. Comparison of antibody production, lymphocyte stimulation and production induced by four commercial Mycoplasma hyopneumoniae bacterins. Swine Health Production 6 (1998) 107-112
27. Thacker E.L., Halbur P.G., Ross R.F., Thanawongnuwech R., and Thacker B.J. Mycoplasma hyopneumoniae Potentiation of porcine reproductive and respiratory syndrome virus-induced pneumonia. Journal of Clinical Microbiology 37 (1999) 620-627
28. Thacker E.L., Thacker B.J., Young T.F., and Halbur P.G. Effect of vaccination on the potentiation of porcine reproductive and respiratory syndrome virus (PRRSV)-induced pneumonia by Mycoplasma hyopneumoniae. Vaccine 18 (2000) 1244-1252
29. Thacker E.L., Thacker B.J., Kuhn M., Hawkins P.A., and Waters W.R. Evaluation of local and systemic immune responses induced by intramuscular injection of a Mycoplasma hyopneumoniae bacterin to pigs. American Journal Veterinary Research 61 (2000) 1384-1389
30. Thacker E.L. Immunology of the porcine respiratory disease complex. Veterinary Clinics of North America. Food Animal Practice, Immunology 17 (2001) 551-565
31. Thacker, B., Wegner, M., Erlandson, K., Maxwell, K., Thompson, J., Thacker, E., 2002. Influence of maternal immunity on Mycoplasma vaccine Respisure One™ efficacy. In: Proceedings 17th International Pig Veterinary Society Congress, Ames, IA, USA, pp. 69-71.
32. Whittlestone P. The role of mycoplasmas in the production of pneumonia in the pig. Pathogenic Mycoplasmas (1972), Associated Scientific Publishers, Amsterdam, Netherlands 263-283
33. Zhang Q., Young T.F., and Ross R.F. Identification and characterization of a Mycoplasma hyopneumoniae adhesin. Infection and Immunity 63 (1995) 1013-1019