Derivative (7)t(7;8): The sole karyotype abnormality in acute promyelocytic leukemia with PML/RARA rearrangement identified by RT-PCR and sequence analysis

Leukemia Research

Volumn 33, Issue 7, 2009, Pages

  Wang, Yewei ^a   Fang, Meiyun ^a   Jing, Yuan ^a   Li, Jianyong ^b   Jiang, Feng ^a   Wang, Yi ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; COMPLEMENTARY DNA; CYTARABINE; HYDROXYUREA; MITOXANTRONE; PIRARUBICIN;

ADULT; BONE MARROW; BONE MARROW EXAMINATION; CANCER REGRESSION; CASE REPORT; CHROMATIN; CHROMOSOME 7; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CONTROLLED STUDY; CYTOCHEMISTRY; FATIGUE; FEMALE; FEVER; FUSION GENE; GENE REARRANGEMENT; HUMAN; HUMAN CELL; KARYOTYPE; LETTER; LEUKEMIA CELL; LEUKOCYTE COUNT; NUCLEOTIDE SEQUENCE; PALLOR; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROMYELOCYTIC LEUKEMIA GENE; RETINOIC ACID RECEPTOR ALPHA GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; UTERUS BLEEDING;

ADULT; CHROMOSOME BANDING; CHROMOSOMES, HUMAN, PAIR 7; CHROMOSOMES, HUMAN, PAIR 8; FEMALE; GENE REARRANGEMENT; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LEUKEMIA, PROMYELOCYTIC, ACUTE; ONCOGENE PROTEINS, FUSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TRANSLOCATION, GENETIC;

EID: 67349275370     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2008.12.002     Document Type: Letter

References (9)

1. In: Shaffer L.G., and Tommerup N. (Eds). ISCN 2005: an International System for Human Cytogenetic Nomenclature (2005), S. Karger, Basel, Switzerland
2. Brockman S.R., Paternoster S.F., Ketterling R.P., and Dewald G.W. New highly sensitive fluorescence in situ hybridization method to detect PML/RARA fusion in acute promyelocytic leukemia. Cancer Genet Cytogenet 145 2 (2003) 144-151
3. Grimwade D., Biondi A., Mozziconacci M.J., Hagemeijer A., Berger R., Neat M., et al. Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party. Blood 96 4 (2000) 1297-1308
4. Ikeda K., Sasaki K., Tasaka T., Nagai M., Kawanishi K., Takahara J., et al. Detection of PML-retinoic acid receptor fusion α transcripts in acute promyelocytic leukemia with trisomy 8 but without t(15;17). Am J Hematol 45 3 (1994) 212-216
5. Han J.Y., Kim K.E., Kim K.H., Park J.I., and Kim J.S. Identification of PML/RARA rearrangement by RT-PCR and sequencing in an acute promyelocytic leukemia without t(15;17) on G-banding and FISH. Leukemia Res 31 (2007) 239-243
6. Vial J.P., Mahon F.X., Pigneux A., Notz A., Lacombe F., Reiffers J., et al. Derivative (7)t(7;8)(q34;q21): a new additional cytogenetic abnormality in acute promyelocytic leukemia. Cancer Genet Cytogenet 14 (2003) 78-81
7. Haimi M., Elhasid R., Weyl Ben-Arush M., Brill-Zamir R., Laeski I., and Gershoni-Baruch R. Derivative (7)t(7;8)(q34;q21): an additional chromosome aberration in acute promyelocytic leukemia-prognostic influence debated. Cancer Genet Cytogenet 153 (2004) 81-83
8. Grimwade D., Walker H., Oliver F., Wheatley K., Harrison C., Harrison G., et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood 92 (1998) 2322-2333
9. Schoch C., Haase D., Fonatsch C., Haferlach T., Loffler H., Schlegelberger B., et al. The significance of trisomy 8 in de novo acute myeloid leukaemia: the accompanying chromosome aberrations determine the prognosis. German AML Cooperative Study Group. Br J Haematol 99 (1997) 605-611