Alpha-helix 1 in the DNA-binding domain of heat shock factor 1 regulates its heat-induced trimerization and DNA-binding

Biochemical and Biophysical Research Communications

Volumn 385, Issue 4, 2009, Pages 612-617

  Lu, Ming ^a   Sohn, Kwang Jea ^a   Kim, Si Won ^a   Li, Chun Ri ^a   Kim, Suhkmann ^a   Kim, Dong Kyoo ^b   Park, Jang Su ^a  

^a Pusan National University   (South Korea)

^b Inje University   (South Korea)

Author keywords

Alpha helix 1 (H1); DNA binding domain (DBD); Heat shock factor 1 (HSF1)

Indexed keywords

HEAT SHOCK TRANSCRIPTION FACTOR 1; PHENYLALANINE; TRYPTOPHAN; TYROSINE;

ALPHA HELIX; ALPHA HELIX1; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; DNA BINDING; HEAT STRESS; NONHUMAN; POINT MUTATION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STABILITY; TRIMERIZATION;

AMINO ACID SEQUENCE; BINDING SITES; DNA; DNA-BINDING PROTEINS; HEAT-SHOCK RESPONSE; HOT TEMPERATURE; HUMANS; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; TRANSCRIPTION FACTORS;

EID: 67349273282     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.05.109     Document Type: Article

References (24)

1. Wu C. Heat shock transcription factors: structure and regulation. Annu. Rev. Cell Dev. Biol. 11 (1995) 441-469
2. Morimoto R.I. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Dev. 12 (1998) 3788-3796
3. Pirkkala L., Nykanen P., and Sistonen L. Roles of the heat shock transcription factors in regulation of the heat shock response and beyond. FASEB J. 15 (2001) 1118-1131
4. Voellmy R. On mechanisms that control heat shock transcription factor activity in metazoan cells. Cell Stress Chaperones 9 (2004) 122-133
5. Peteranderl R., and Nelson H.C. Trimerization of the heat shock transcription factor by a triple-stranded α-helical coiled-coil. Biochemistry 31 (1992) 12272-12276
6. Peteranderl R., Rabenstein M., Shin Y.K., Liu C.W., Wemmer D.E., King D.S., and Nelson H.C. Biochemical and biophysical characterization of the trimerization domain from the heat shock transcription factor. Biochemistry 38 (1999) 3559-3569
7. Sorger P.K. Heat shock factor and the heat shock response. Cell 65 (1991) 363-366
8. Lis J., and Wu C. Protein traffic on the heat shock promoter: parking, stalling, and trucking along. Cell 74 (1993) 1-4
9. Lu M., Kim H.-E., Li C.-R., Kim S., Kwak I.-J., Lee Y.-J., Kim S.-S., Moon J.-Y., Kim C.H., Kim D.-K., Kang H.S., and Park J.-S. Two distinct disulfide bonds formed in human heat shock transcription factor 1 act in opposition to regulate its DNA binding activity. Biochemistry 47 (2008) 6007-6015
10. Lu M., Lee Y.-J., Park S.-M., Kang H.S., Kang S.W., Kim S., and Park J.-S. Aromatic-participant interactions are essential for disulfide-bond-based trimerization in human heat shock transcription factor 1. Biochemistry 48 (2009) 3795-3797
11. Damberger F.F., Pelton J.G., Harrison C.J., Nelson H.C., and Wemmer D.E. Solution structure of the DNA-binding domain of the heat shock transcription factor determined by multidimensional heteronuclear magnetic resonance spectroscopy. Protein Sci. 3 (1994) 1806-1821
12. Damberger F.F., Pelton J.G., Liu C., Cho H., Harrison C.J., Nelson H.C., and Wemmer D.E. Refined solution structure and dynamics of the DNA-binding domain of the heat shock factor from Kluyveromyces lactis. J. Mol. Biol. 254 (1995) 704-719
13. Hardy J.A., Walsh S.T.R., and Nelson H.C.M. Role of an α-helical bulge in the yeast heat shock transcription factor. J. Mol. Biol. 295 (2000) 393-409
14. Littlefield O., and Nelson H.C. A new use for the 'wing' of the 'winged' helix-turn-helix motif in the HSF-DNA cocrystal. Nat. Struct. Biol. 6 (1999) 464-470
15. Cicero M.P., Hubl S.T., Harrison C.J., Littlefield O., Hardy J.A., and Nelson H.C. The wing in yeast heat shock transcription factor (HSF) DNA-binding domain is required for full activity. Nucleic Acids Res. 29 (2001) 1715-1723
16. Ahn S.-G., Liu P.C.C., Klyachko K., Morimoto R.I., and Thiele1 D.J. The loop domain of heat shock transcription factor 1 dictates DNA-binding specificity and responses to heat stress. Gene Dev. 15 (2001) 2134-2145
17. Soncin F., Prevelige R., and Calderwood S.K. Expression and purification of human heat-shock transcription factor 1. Protein Expre. Purif. 9 (1997) 27-32
18. Kim H.R., Kang H.S., and Kim H.D. Geldanamycin induces heat shock protein expression through activation of HSF1 in K562 erythroleukemic cells. IUBMB Life 48 (1999) 429-433
19. Park J.-S., Wang M., Park S.J., and Lee S.H. Zinc-finger of replication protein A, a non-DNA binding element, regulates its DNA binding activity through redox. J. Biol. Chem. 274 (1999) 29075-29080
20. Kelly S.M., Jess T.J., and Price N.C. How to study proteins by circular dichroism. Biochim. Biophys. Acta 1751 (2005) 119-139
21. Vuister G.W., Kim S.-J., Orosz A., Marquardt J., Wu C., and Bax A. Solution structure of the DNA-binding domain of Drosophila heat shock transcription factor. Nature Struct. Biol. 1 (1994) 605-614
22. Liwo A., Czaplewski C., Ołdziej S., and Scheraga H.A. Computational techniques for efficient conformational sampling of proteins. Curr. Opin. Struct. Biol. 18 (2008) 134-139
23. Feller S.E. Molecular dynamics simulations as a complement to nuclear magnetic resonance and X-ray diffraction measurements. Methods Mol. Biol. 400 (2007) 89-102
24. Burley S.K., and Petsko G.A. Aromatic-aromatic interaction: a mechanism of protein structure stabilization. Science 229 (1985) 23-28