Nanoencapsulation increases quinine antimalarial efficacy against Plasmodium berghei in vivo

International Journal of Antimicrobial Agents

Volumn 34, Issue 2, 2009, Pages 156-161

  Haas, Sandra Elisa ^a   Bettoni, Clarissa Cassini ^a   de Oliveira, Laura Kausburg ^a   Guterres, Sílvia Stanisçuaski ^a   Dalla Costa, Teresa ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Antimalarial efficacy; Erythrocyte partition coefficient; Nanocapsules; Pharmacokinetics; Plasmodium berghei; Quinine

Indexed keywords

POLYCAPROLACTONE; POLYSORBATE 80; QUININE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG CLEARANCE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG ELIMINATION; DRUG PENETRATION; DRUG STABILITY; HALF LIFE TIME; IN VIVO STUDY; MEAN RESIDENCE TIME; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PARTITION COEFFICIENT; PLASMODIUM BERGHEI INFECTION; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SURVIVAL RATE; ZETA POTENTIAL;

ANIMALS; ANTIMALARIALS; DRUG CARRIERS; ERYTHROCYTES; INJECTIONS, INTRAVENOUS; MALARIA; MALE; NANOPARTICLES; PLASMODIUM BERGHEI; QUININE; RATS; RATS, WISTAR; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 67349260771     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2009.02.024     Document Type: Article

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