Frequent spontaneous eyeblink activity associated with reduced conjunctival surface (trigeminal nerve) tactile sensitivity

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 247, Issue 7, 2009, Pages 939-946

  Doughty, Michael J ^a   Naase, Taher ^a   Button, Norman F ^a  

^a GLASGOW CALEDONIAN UNIVERSITY   (United Kingdom)

Author keywords

Conjunctival tactile sensitivity; Corneal tactile sensitivity; Eyeblinking; Primary gaze

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; CORNEA SENSIBILITY; EYE MOVEMENT; EYELID REFLEX; GAZE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SLIT LAMP; TRIGEMINAL NERVE; VIDEORECORDING; VISUAL SYSTEM EXAMINATION; VOLUNTEER;

ADULT; BLINKING; CONJUNCTIVA; CORNEA; HUMANS; MALE; PHYSICAL STIMULATION; SENSORY THRESHOLDS; TIME FACTORS; TOUCH; TRIGEMINAL NERVE; VIDEO RECORDING; YOUNG ADULT;

EID: 67349258497     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-008-1028-8     Document Type: Article

References (46)

1. Ponder E, Kennedy WP (1927) On the act of blinking. Q J Exp Physiol 18:89-110
2. Stern JA, Walrath LC, Goldstein R (1984) The endogenous eyeblink. Psychobiol 21:22-33
3. Karson CN (1988) Physiology of normal and abnormal blinking. Adv Neurol 49:25-37
4. Vreugdenhil H, Brouwers P, Wolters P, Bakker D, Moss H (1997) Spontaneous eye blinking, a measure of dopaminergic function, in children with acquired immunodeficiency syndrome. Arch Pediatr Adolesc Med 151:1025-1032
5. Tsubota K, Kwong KK, Lee T-Y, Nakamura J, Cheng H-M (1999) Functional MRI of brain activation by eye blinking. Exp Eye Res 69:1-7. doi: 10.1006/exer.1999.0660
6. Bour LJ, Aramideh M, Ongerboer de Visser BW (2000) Neurophysiological aspects of eye and eyelid movements during blinking in humans. J Neurophysiol 83:166-176
7. Doughty MJ (2001) Consideration of three types of spontaneous eyeblink activity in normal humans: During reading and video display terminal use, in primary gaze, and while in conversation. Optom Vis Sci 78:712-725. doi: 10.1097/00006324-200110000-00011
8. Bentivoglio AR, Bressman SB, Cassetta E, Carretta D, Tonali P, Albanese A (1997) Analysis of blink rate patterns in normal subjects. Mov Disord 12:1028-1034. doi: 10.1002/mds.870120629
9. Zaman ML, Doughty MJ, Button NF (1999) The exposed ocular surface and its relationship to spontaneous eyeblink rate in elderly Caucasians. Exp Eye Res 67:681-686. doi: 10.1006/exer.1998.0571
10. Mori A, Egami F, Nakamori K, Ohtsuki T, Aikawa K, Shintani M, Matsumoto Y, Goto E, Tsubota K (2008) Quantitative videographic analysis of blink patterns of newscasters. Graefes Arch Clin Exp Ophthalmol 246:1449-1453. doi: 10.1007/s00417-008-0887-3
11. Sforza C, Rango M, Galante D, Bresolin N, Ferrario VF (2008) Spontaneous blinking in healthy persons: An optokinetic study of eyelid motion. Ophthalmic Physiol Opt 28:345-353. doi: 10.1111/j.1475-1313.2008.00577.x
12. Kleno J, Wolkoff P (2004) Changes in eye blink frequency as a measure of trigeminal stimulation by exposure to limonene oxidation products, isoprene oxidation products and nitrate radicals. Int Arch Occup Environ Health 77:235-243. doi: 10.1007/s00420-003-0502-1
13. Tsubota K, Hara S, Okusawa Y, Egami F, Ohtsuki T, Nakamori K (1996) Quantitative videographic analysis of blinking in normal subjects and patients with dry eye. Arch Ophthalmol 114:715-720
14. Acosta MC, Gallar J, Belmonte C (1999) The influence of eye solutions on blinking and ocular comfort at rest and during work at a video display terminals. Exp Eye Res 68:663-669. doi: 10.1006/exer.1998.0656
15. Walker JC, Kendal-Reed M, Utell MJ, Cain WS (2001) Human breathing and eye blink rate responses to airborne chemicals. Environ Health Perspect 109(suppl 4):507-512. doi: 10.2307/3454661
16. Wolkoff P, Nojgaard JK, Toiano P, Picoli B (2005) Eye complaints in the office environment: Precorneal tear film integrity influenced by eye blinking frequency. Occup Environ Med 62:4-12. doi: 10.1136/ oem.2004.016030
17. Kugelberg E (1952) Facial reflexes. Brain 75:385-396. doi: 10.1093/brain/ 75.3.385
18. Millodot M (1973) Objective measurement of corneal sensitivity. Acta Ophthalmol (Copenh) 51:325-334
19. Gallar J, Acosta MC, Gutiérrez AR, Belmonte C (2007) Impulse activity in corneal sensory nerve fibers after photorefractive keratectomy. Invest Ophthalmol Vis Sci 48:4033-4037. doi: 10.1167/ iovs.07-0012
20. Huber P (1962) Untersuchungen über die Beeinflussung des spontanen Lidschlages durch Lokal-Anaesthetica. Graefes Arch Clin Exp Ophthalmol (forerunner) 164:594-611. doi: 10.1007/BF00682809
21. Collins M, Seeto R, Campbell L, Ross M (1989) Blinking and corneal sensitivity. Acta Ophthalmol (Copenh) 67:525-531
22. Nakamori K, Odawara M, Nakajima T, Mizutani T, Tsubota K (1997) Blinking is controlled primarily by ocular surface conditions. Am J Ophthalmol 124:24-30
23. Fruedenthaler N, Neuf H, Kadner G, Schlote T (2003) Characteristics of spontaneous eyeblink activity during video display terminal use in healthy volunteers. Graefes Arch Clin Exp Ophthalmol 241:914-920. doi: 10.1007/s00417-003-0786-6
24. Naase T, Doughty MJ, Button NF (2005) An assessment of the pattern of spontaneous eyeblink activity under the influence of topical ocular anaesthesia. Graefes Arch Clin Exp Ophthalmol 243:306-312. doi: 10.1007/ s00417-004-0990-z
25. Barbarato G, Ficca G, Muscettola G, Fichele M, Beatrice M, Rinaldi F (2000) Diurnal variation in spontaneous eye-blink rate. Psychiatry Res 93:145-151. doi: 10.1016/S0165-1781(00)00108-6
26. Doughty MJ, Blades KA, Ibrahim N (2002) Assessment of the number of eye symptoms and the impact of some confounding variable for office staff in non-air-conditioned buildings. Ophthalmic Physiol Opt 22:143-155. doi: 10.1046/j.1475-1313.2002.00013.x
27. Zaman ML, Doughty MJ (1997) Some methodological issues in the assessment of the spontaneous eyeblink in man. Ophthalmic Physiol Opt 17:421-432
28. Doughty MJ (2002) Further assessment of gender- and blink pattern-related differences in the spontaneous eyeblink activity in primary gaze in young adult humans. Optom Vis Sci 79:439-447. doi: 10.1097/00006324-200207000-00013
29. Cochet P, Bonnet R (1960) L'esthésie cornéene. Sa mesure clinique. Clin Ophtalmol 4:3-27
30. Terry RL, Schnider CM, Holden BA, Cornish R, Grant T, Sweeney D, La Hood D, Back A (1993) CCLRU standards for success of daily and extended wear contact lenses. Optom Vis Sci 70:234-243. doi: 10.1097/ 00006324-199303000-00011
31. Doughty MJ, Naase T (2006) Further analysis of the human spontaneous eyeblink rate by a cluster analysis-based approach to categorize individuals with 'normal' versus 'frequent' eye blink activity. Eye Contact Lens 32:294-299. doi: 10.1097/01.icl.0000224359.32709.4d
32. Schellini A, Sampaio AA, Hoyama E, Cruz AAV, Padovani CR (2005) Spontaneous eye blink analysis in the normal individual. Orbit 24:239-242. doi: 10.1080/01676830590922057
33. De Pavia CS, Pflugfelder SC (2004) Corneal epitheliopathy of dry eye induces hyperesthesia to mechanical air jet stimulation. Am J Ophthalmol 137:109-115. doi: 10.1016/S0002-9394(03)00897-3
34. Jalavisto E, Orma E, Tawast M (1951) Ageing and relation between stimulus intensity and duration in corneal sensibility. Acta Physiol Scand 23:224-233. doi: 10.1111/j.1748-1716.1951.tb00812.x
35. Manning KA, Evinger C (1986) Different forms of blinks and their two-stage control. Exp Brain Res 64:579-588. doi: 10.1007/BF00340495
36. Helland M, Horgen G, Kvikstad TM, Garthus T, Bruenech JR, Aaras A (2008) Musculoskeletal, visual and psychsocial stress in VDU operators after moving to an ergonomically designed office landscape. Appl Ergon 39:284-295. doi: 10.1016/j.apergo.2007.10.005
37. Aakre BM, Doughty MJ (2007) Are there differences between 'visual symptoms' and specific ocular symptoms associated with video display terminal (VDT) use? Cont Lens Anterior Eye 30:174-182. doi: 10.1016/ j.clae.2007.01.001
38. McMonies CW (2007) Incomplete blinking: Exposure keratopathy, lid wiper epitheliopathy, dry eye, refractive surgery, and dry contact lenses. Cont Lens Anterior Eye 30:37-51. doi: 10.1016/j.clae.2006.12.002
39. Peshori KR, Schicatano EJ, Gopalaswamy R, Sahay E, Evinger C (2001) Aging of the trigmeninal blink system. Exp Brain Res 136:351-363. doi: 10.1007/s002210000585
40. Dimitrova A, Weber J, Maschke M, Elles H-G, Kolb FP, Forsting M, Diener H-C, Timmann D (2002) Eyeblink-related areas in human cerebellum shown by fMRI. Hum Brain Mapp 17:100-115. doi: 10.1002/hbm.10056
41. Powers AS, Schicatano EJ, Basso MA, Evinger C (1997) To blink or not to blink: Inhibition and facilitation of reflex blinks. Exp Brain Res 113:283-290. doi: 10.1007/BF02450326
42. Xu KP, Yagi Y, Tsubota K (1996) Decrease in corneal sensitivity and change in tear function in dry eye. Cornea 15:235-239. doi: 10.1097/ 00003226-199605000-00002
43. Bourcier T, Acosta MC, Borderie V, Borras F, Gallar J, Bury T, Laroche L, Belmonte C (2005) Decreased corneal sensitivity in patients with dry eye. Invest Ophthalmol Vis Sci 46:2341-2345. doi: 10.1167/iovs.04-1426
44. Ongerboer de Visser BW, Bour LJ (2006) Eye and eyelid movements during blinking: An eye blink centre? Clin Neurophysiol 58(suppl):16-25
45. Peterson J, Allison LW (1931) Controls of the eye-wink mechanism. J Exp Psychol 14:144-154. doi: 10.1037/h0070197
46. Colzato LS, van Wouwe NC, Hommel B (2007) Spontaneous eyeblink rate predicts the strength of visuomotor binding. Neuropsychologia 45:2387-2392. doi: 10.1016/j.neuropsychologia.2007.03.004