Detection of cocaine and its metabolites in urine using solid phase extraction-ion mobility spectrometry with alternating least squares

Forensic Science International

Volumn 189, Issue 1-3, 2009, Pages 54-59

  Lu, Yao ^a   O'Donnell, Ryan M ^a   Harrington, Peter B ^a  

^a Center for Intelligent Chemical Instrumentation   (United States)

Author keywords

Alternating least square; Cocaine; Ion mobility spectroscopy; Solid phase extraction

Indexed keywords

BENZOYLECGONINE; COCAINE; HOMOCOCAINE;

ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG SCREENING; INTERMETHOD COMPARISON; ION MOBILITY SPECTROMETRY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; URINALYSIS;

COCAINE; DOPAMINE UPTAKE INHIBITORS; FORENSIC TOXICOLOGY; HUMANS; MASS SPECTROMETRY; MODELS, STATISTICAL; SOLID PHASE MICROEXTRACTION; SUBSTANCE ABUSE DETECTION;

EID: 67349257788     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2009.04.007     Document Type: Article

References (20)

1. http://www.oas.samhsa.gov (Accessed in August 2008).
2. Casale J.F., Boudreau D.K., and Jones L.M. Tropane ethyl esters in illicit cocaine: isolation, detection, and determination of new manufacturing by-products from the clandestine purification of crude cocaine base with ethanol. J. Forensic Sci. 53 (2008) 661-667
3. Telepchak M.J., August T.F., and Chaney G. Forensic and Clinical Applications of Solid Phase Extraction (2004), Humana Press, Totowa, NJ
4. Cardona P.S., Chaturvedi A.K., Soper J.W., and Canfield D.V. Simultaneous analyses of cocaine, cocaethylene, and their possible metabolic and pyrolytic products. Forensic Sci. Int. 157 (2006) 46-56
5. Anderson R.A., Ariffin M.M., Cormack P.A.G., and Miller E.I. Comparison of molecularly imprinted solid-phase extraction (MISPE) with classical solid-phase extraction (SPE) for the detection of benzodiazepines in post-mortem hair samples. Forensic Sci. Int. 174 (2008) 40-46
6. Clauwaert K., Decalestecker T., Mortier K., Lambert W., Deforce D., Van Peteghem C., and Van Bocxlaer J. The determination of cocaine, benzoylecgonine, and cocaethylene in small-volume oral fluid samples by liquid chromatography-quadrupole-time-of-flight mass spectrometry. J. Anal. Toxicol. 28 (2004) 655-659
7. Caufield W.V., and Stewart J.T. Rapid determination of selected drugs of abuse in human plasma using a monolithic silica HPLC column and solid phase extraction. J. Liq. Chromatogr. Relat. Technol. 25 (2002) 2977-2998
8. Srinivasan K., Wang P., Eley A.T., White C.A., and Bartlett M.G. Liquid chromatography-tandem mass spectrometry analysis of cocaine and its metabolites from blood, amniotic fluid, placental and fetal tissues: study of the metabolism and distribution of cocaine in pregnant rats. J. Chromatogr. B 745 (2000) 287-303
9. Xia Y., Wang P.P., Bartlett M.G., Solomon H.M., and Busch K.L. An LC-MS-MS method for the comprehensive analysis of cocaine and cocaine metabolites in meconium. Anal. Chem. 72 (2000) 764-771
10. Wu A.H.B., Bristol B., Sexton K., Cassella-McLane G., Holtman V., and Hill D.W. Adulteration of urine by "Urine Luck". Clin. Chem. 45 (1999) 1051-1057
11. Eiceman G.A. Ion mobility spectrometry as detector and sensor for chemical warfare agents and toxic industrial chemicals. Abst. Pap. Am. Chem. Soc. 224 (2002) U145-U1145
12. Rearden P., and Harrington P.B. Rapid screening of precursor and degradation products of chemical warfare agents in soil by solid-phase microextraction ion mobility spectrometry (SPME-IMS). Anal. Chim. Acta 545 (2005) 13-20
13. Eiceman G.A. Ion-mobility spectrometry as a fast monitor of chemical composition. Trac-Trends Anal. Chem. 21 (2002) 259-275
14. O'Donnell R.M., Sun X.B., and Harrington P.D. Pharmaceutical applications of ion mobility spectrometry. Trac-Trends Anal. Chem. 27 (2008) 44-53
15. Eiceman G.A., and Karpas Z. Ion Mobility Spectrometry (2005), CRC Press, Boca Raton, FL
16. Harrington P.D., Reese E.S., Rauch P.J., Hu L.J., and Davis D.M. Interactive self-modeling mixture analysis of ion mobility spectra. Appl. Spectrosc. 51 (1997) 808-816
17. Van Benthem M.H., Keenan M.R., and Haaland D.M. Application of equality constraints on variables during alternating least squares procedures. J. Chemom. 16 (2002) 613-622
18. Bezemer E., and Rutan S.C. Three-way alternating least squares using three-dimensional tensors in MATLAB (R). Chemom. Intell. Lab. Syst. 60 (2002) 239-251
19. de Juan A., Rutan S.C., Tauler R., and Massart D.L. Comparison between the direct trilinear decomposition and the multivariate curve resolution-alternating least squares methods for the resolution of three-way data sets. Chemom. Intell. Lab. Syst. 40 (1998) 19-32
20. Cao L., and Harrington P.D. ALS to modeling of ion mobility spectra. Int. J. Ion Mobility Spectrom. 7 (2004) 9-11