Mature, Adipocyte Derived, Dedifferentiated Fat Cells Can Differentiate Into Smooth Muscle-Like Cells and Contribute to Bladder Tissue Regeneration

Journal of Urology

Volumn 182, Issue 1, 2009, Pages 355-365

  Sakuma, Takahiro ^a   Matsumoto, Taro ^a   Kano, Koichiro ^b   Fukuda, Noboru ^a,b   Obinata, Daisuke ^a   Yamaguchi, Kenya ^a   Yoshida, Toshio ^a   Takahashi, Satoru ^a   Mugishima, Hideo ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NIHON UNIVERSITY   (Japan)

Author keywords

adipocytes; cell dedifferentiation; myocytes, smooth muscle; regeneration; urinary bladder

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FAT; GREEN FLUORESCENT PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER INJURY; CELL CULTURE; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE REGENERATION;

ADIPOCYTES; ANIMALS; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CELL TRANSPLANTATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; HUMANS; MALE; MICE; MICE, INBRED C57BL; MYOCYTES, SMOOTH MUSCLE; PROBABILITY; RANDOM ALLOCATION; REGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; STATISTICS, NONPARAMETRIC; URINARY BLADDER; URINARY BLADDER DISEASES;

EID: 67349256739     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2009.02.103     Document Type: Article

References (20)

1. Atala A., Bauer S.B., Soker S., Yoo J.J., and Retik A.B. Tissue-engineered autologous bladders for patients needing cystoplasty. Lancet 367 (2006) 1241
2. Yokoyama T., Huard J., Pruchnic R., Yoshimura N., Qu Z., Cao B., et al. Muscle-derived cell transplantation and differentiation into lower urinary tract smooth muscle. Urology 57 (2001) 826
3. De Coppi P., Callegari A., Chiavegato A., Gasparotto L., Piccoli M., Taiani J., et al. Amniotic fluid and bone marrow derived mesenchymal stem cells can be converted to smooth muscle cells in the cryo-injured rat bladder and prevent compensatory hypertrophy of surviving smooth muscle cells. J Urol 177 (2007) 369
4. Jack G.S., Almeida F.G., Zhang R., Alfonso Z.C., Zuk P.A., and Rodriguez L.V. Processed lipoaspirate cells for tissue engineering of the lower urinary tract: implications for the treatment of stress urinary incontinence and bladder reconstruction. J Urol 174 (2005) 2041
5. Stolzing A., Jones E., McGonagle D., and Scutt A. Age-related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies. Mech Ageing Dev 129 (2008) 163
6. Zuk P.A., Zhu M., Mizuno H., Huang J., Futrell J.W., Katz A.J., et al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7 (2001) 211
7. McIntosh K., Zvonic S., Garrett S., Mitchell J.B., Floyd Z.E., Hammill L., et al. The immunogenicity of human adipose-derived cells: temporal changes in vitro. Stem Cells 24 (2006) 1246
8. Sugihara H., Yonemitsu N., Miyabara S., and Yun K. Primary cultures of unilocular fat cells: characteristics of growth in vitro and changes in differentiation properties. Differentiation 31 (1986) 42
9. Sugihara H., Yonemitsu N., Miyabara S., and Toda S. Proliferation of unilocular fat cells in the primary culture. J Lipid Res 28 (1987) 1038
10. Shigematsu M., Watanabe H., and Sugihara H. Proliferation and differentiation of unilocular fat cells in the bone marrow. Cell Struct Funct 24 (1999) 89
11. Yagi K., Kondo D., Okazaki Y., and Kano K. A novel preadipocyte cell line established from mouse adult mature adipocytes. Biochem Biophys Res Commun 321 (2004) 967
12. Matsumoto T., Kano K., Kondo D., Fukuda N., Iribe Y., Tanaka N., et al. Mature adipocyte-derived dedifferentiated fat cells exhibit multilineage potential. J Cell Physiol 215 (2008) 210
13. Nobusue H., Endo T., and Kano K. Establishment of a preadipocyte cell line derived from mature adipocytes of GFP transgenic mice and formation of adipose tissue. Cell Tissue Res 332 (2008) 435
14. Hinz B., Phan S.H., Thannickal V.J., Galli A., Bochaton-Piallat M.L., and Gabbiani G. The myofibroblast: one function, multiple origins. Am J Pathol 170 (2007) 1807
15. Chen F.G., Zhang W.J., Bi D., Liu W., Wei X., Chen F.F., et al. Clonal analysis of nestin(-) vimentin(+) multipotent fibroblasts isolated from human dermis. J Cell Sci 120 (2007) 2875
16. Darby I.A., and Hewitson T.D. Fibroblast differentiation in wound healing and fibrosis. Int Rev Cytol 257 (2007) 143
17. Kale V.P. Differential activation of MAPK signaling pathways by TGF-beta1 forms the molecular mechanism behind its dose-dependent bidirectional effects on hematopoiesis. Stem Cells Dev 13 (2004) 27
18. Kanematsu A., Yamamoto S., Iwai-Kanai E., Kanatani I., Imamura M., Adam R.M., et al. Induction of smooth muscle cell-like phenotype in marrow-derived cells among regenerating urinary bladder smooth muscle cells. Am J Pathol 166 (2005) 565
19. Clark B.R., and Keating A. Biology of bone marrow stroma. Ann N Y Acad Sci 770 (1995) 70
20. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131 (2007) 861