Suicide, stress and serotonin receptor 1A promoter polymorphism -1019C>G in Slovenian suicide victims

European Archives of Psychiatry and Clinical Neuroscience

Volumn 259, Issue 4, 2009, Pages 234-238

  Videtič, Alja ^a   Zupanc, Tomaž ^a   Pregelj, Peter ^b   Balažic, Jože ^a   Tomori, Martina ^b   Komel, Radovan ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b UNIVERSITY PSYCHIATRIC HOSPITAL   (Slovenia)

Author keywords

Polymorphism; Serotonin receptor 1A; Slavic Slovenian population; Stressful life events; Suicide

Indexed keywords

AUTORECEPTOR; SEROTONIN 1A RECEPTOR;

ADULT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; LIFE EVENT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RISK FACTOR; STATISTICAL SIGNIFICANCE; STRESS; SUICIDE;

ADULT; AGED; DEPRESSIVE DISORDER; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LIFE CHANGE EVENTS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RECEPTOR, SEROTONIN, 5-HT1A; RISK FACTORS; SEX FACTORS; SLOVENIA; STRESS, PSYCHOLOGICAL; SUICIDE;

EID: 67349252821     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-008-0861-4     Document Type: Article

References (25)

1. PR Albert S Lemonde 2004 5-HT1A receptors, gene repression, and depression: guilt by association Neuroscientist 10 575 593 (Pubitemid 39546399)
2. S Anttila K Huuhka M Huuhka R Rontu M Hurme E Leinonen T Lehtimaki 2007 Interaction between 5-HT1A and BDNF genotypes increases the risk of treatment-resistant depression J Neural Transm 114 1065 1068
3. V Arango MD Underwood M Boldrini H Tamir SA Kassir S Hsiung JJ Chen JJ Mann 2001 Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims Neuropsychopharmacology 25 892 903 (Pubitemid 34031894)
4. V Arango MD Underwood AV Gubbi JJ Mann 1995 Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims Brain Res 688 121 133
5. M Asberg P Thoren L Traskman L Bertilsson V Ringberger 1976 "Serotonin depression"-a biochemical subgroup within the affective disorders? Science 191 478 480
6. M Asberg L Traskman P Thoren 1976 5-HIAA in the cerebrospinal fluid. A biochemical suicide predictor? Arch Gen Psychiatry 33 1193 1197
7. P Baud 2005 Personality traits as intermediary phenotypes in suicidal behavior: genetic issues Am J Med Genet C Semin Med Genet 133 34 42 (Pubitemid 40194127)
8. B Bondy A Buettner P Zill 2006 Genetics of suicide Mol Psychiatry 11 336 351
9. T Brugha P Bebbington C Tennant J Hurry 1985 The list of threatening experiences: a subset of 12 life event categories with considerable long-term contextual threat Psychol Med 15 189 194 (Pubitemid 15133493)
10. F Chaouloff O Berton P Mormede 1999 Serotonin and stress Neuropsychopharmacology 21 28S 32S (Pubitemid 29396468)
11. CJ Hong TJ Chen YW Yu SJ Tsai 2006 Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder Pharmacogenomics J 6 27 33 (Pubitemid 43118308)
12. YY Huang C Battistuzzi MA Oquendo J Harkavy-Friedman L Greenhill G Zalsman B Brodsky V Arango DA Brent JJ Mann 2004 Human 5-HT1A receptor C(-1019)G polymorphism and psychopathology Int J Neuropsychopharmacol 7 441 451 (Pubitemid 39648074)
13. JN Joyce A Shane N Lexow A Winokur MF Casanova JE Kleinman 1993 Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics Neuropsychopharmacology 8 315 336 (Pubitemid 23162958)
14. G Koller B Bondy UW Preuss P Zill M Soyka 2006 The C(-1019)G 5-HT1A promoter polymorphism and personality traits: no evidence for significant association in alcoholic patients Behav Brain Funct 2 7
15. S Lemonde G Turecki D Bakish L Du PD Hrdina CD Bown A Sequeira N Kushwaha SJ Morris A Basak XM Ou PR Albert 2003 Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide J Neurosci 23 8788 8799 (Pubitemid 37176660)
16. N Nishiguchi O Shirakawa H Ono A Nishimura H Nushida Y Ueno K Maeda 2002 Lack of an association between 5-HT1A receptor gene structural polymorphisms and suicide victims Am J Med Genet 114 423 425 (Pubitemid 34525239)
17. TJ Pucadyil S Kalipatnapu A Chattopadhyay 2005 The serotonin 1A receptor: a representative member of the serotonin receptor family Cell Mol Neurobiol 25 553 580 (Pubitemid 41186261)
18. J Sawiniec K Borkowski G Ginalska H Lewandowska-Stanek 2007 Association between 5-hydroxytryptamine 1A receptor gene polymorphism and suicidal behavior Przegl Lek 64 208 211
19. A Serretti L Mandelli I Giegling B Schneider AM Hartmann A Schnabel K Maurer HJ Moller D Rujescu 2007 HTR2C and HTR1A gene variants in German and Italian suicide attempters and completers Am J Med Genet B Neuropsychiatr Genet 144B 291 299 (Pubitemid 46642017)
20. Sunnqvist 2008 Eur Arch Psychiatry Clin Neurosci 258 456
21. A Videtic G Pungercic IZ Pajnic T Zupanc J Balazic M Tomori R Komel 2006 Association study of seven polymorphisms in four serotonin receptor genes on suicide victims Am J Med Genet B Neuropsychiatr Genet 141 669 672 (Pubitemid 44434670)
22. D Wasserman T Geijer M Sokolowski V Rozanov J Wasserman 2007 Nature and nurture in suicidal behavior, the role of genetics: some novel findings concerning personality traits and neural conduction Physiol Behav 92 245 249 (Pubitemid 47374255)
23. D Wasserman T Geijer M Sokolowski V Rozanov J Wasserman 2006 The serotonin 1A receptor C(-1019)G polymorphism in relation to suicide attempt Behav Brain Funct 2 14 (Pubitemid 43757145)
24. World Health Organisation (2008) Health topics. Suicide: Suicide Prevention and Special Programmes, Geneva
25. S Wu DE Comings 1999 A common C-1018G polymorphism in the human 5-HT1A receptor gene Psychiatr Genet 9 105 106