Caffeine withdrawal, acute effects, tolerance, and absence of net beneficial effects of chronic administration: Cerebral blood flow velocity, quantitative EEG, and subjective effects

Psychopharmacology

Volumn 204, Issue 4, 2009, Pages 573-585

  Sigmon, Stacey C ^a   Herning, Ronald I ^b   Better, Warren ^b   Cadet, Jean L ^b   Griffiths, Roland R ^c  

^a FLETCHER ALLEN HEALTH CARE   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Caffeine; Cerebral blood flow velocity; EEG; Humans; Physical dependence; Subjective effects; Tolerance; Withdrawal

Indexed keywords

CAFFEINE; PLACEBO;

ACUTE DRUG ADMINISTRATION; ADULT; ANTERIOR CEREBRAL ARTERY; ARTICLE; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; CHRONIC DRUG ADMINISTRATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG TOLERANCE; DRUG WITHDRAWAL; ELECTROENCEPHALOGRAM; EMOTION; FATIGUE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MIDDLE CEREBRAL ARTERY; NORMAL HUMAN; PRIORITY JOURNAL; QUESTIONNAIRE; SIDE EFFECT; THETA RHYTHM; WITHDRAWAL SYNDROME;

ADULT; ANTERIOR CEREBRAL ARTERY; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; CEREBROVASCULAR CIRCULATION; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DRUG TOLERANCE; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; MIDDLE CEREBRAL ARTERY; QUESTIONNAIRES; SUBSTANCE WITHDRAWAL SYNDROME; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; YOUNG ADULT;

EID: 67349246827     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-009-1489-4     Document Type: Article

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