Expression of nestin mRNA is a differentiation marker in thyroid tumors

Cancer Letters

Volumn 280, Issue 1, 2009, Pages 61-64

  Yamada, Hiroya ^a,b   Takano, Toru ^a   Ito, Yasuhiro ^c   Matsuzuka, Fumio ^c   Miya, Akihiro ^c   Kobayashi, Kaoru ^c   Yoshida, Hiroshi ^c   Watanabe, Mikio ^b   Iwatani, Yoshinori ^b   Miyauchi, Akira ^c  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KUMA HOSPITAL   (Japan)

Author keywords

Anaplastic thyroid carcinoma; Cancer stem cell; Gene expression; Nestin; Thyroid transcription factor 1

Indexed keywords

MESSENGER RNA; NESTIN; THYROID TRANSCRIPTION FACTOR 1;

ANAPLASTIC CARCINOMA; ARTICLE; CANCER STEM CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; THYROID CARCINOMA;

ADENOMA; CARCINOMA; CELL DIFFERENTIATION; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GOITER; HUMANS; INTERMEDIATE FILAMENT PROTEINS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THYROID NEOPLASMS; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 67349246764     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.02.006     Document Type: Article

References (24)

1. Reya T., Morrison S.J., Clarke M.F., and Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 414 (2001) 105-111
2. Ain K.B. Anaplastic thyroid carcinoma: behavior, biology, and therapeutic approaches. Thyroid 8 (1998) 715-726
3. Takano T. Fetal cell carcinogenesis of the thyroid: theory and practice. Semin. Cancer Biol. 17 (2007) 233-240
4. Takano T., and Amino N. Fetal cell carcinogenesis: a new hypothesis for better understanding of thyroid carcinoma. Thyroid 15 (2005) 432-438
5. Zhang P., Zuo H., Ozaki T., Nakagomi N., and Kakudo K. Cancer stem cell hypothesis in thyroid cancer. Pathol. Int. 56 (2006) 485-489
6. Lendahl U., Zimmerman L.B., and McKay R.D. CNS stem cells express a new class of intermediate filament protein. Cell 60 (1990) 585-595
7. Almqvist P.M., Mah R., Lendahl U., Jacobsson B., and Hendson G. Immunohistochemical detection of nestin in pediatric brain tumors. J. Histochem. Cytochem. 50 (2002) 147-158
8. Berman D.M., Karhadkar S.S., Hallahan A.R., Pritchard J.I., Eberhart C.G., Watkins D.N., Chen J.K., Cooper M.K., Taipale J., Olson J.M., and Beachy P.A. Medulloblastoma growth inhibition by hedgehog pathway blockade. Science 297 (2002) 1559-1561
9. Dahlstrand J., Collins V.P., and Lendahl U. Expression of the class VI intermediate filament nestin in human central nervous system tumors. Cancer Res. 52 (1992) 5334-5341
10. Kobayashi M., Sjoberg G., Soderhall S., Lendahl U., Sandstedt B., and Sejersen T. Pediatric rhabdomyosarcomas express the intermediate filament nestin. Pediatr. Res. 43 (1998) 386-392
11. Yang X.H., Wu Q.L., Yu X.B., Xu C.X., Ma B.F., Zhang X.M., Li S.N., Lahn B.T., and Xiang A.P. Nestin expression in different tumours and its relevance to malignant grade. J. Clin. Pathol. 61 (2008) 467-473
12. Takano T., Miyauchi A., Yoshida H., Hasegawa Y., Kuma K., and Amino N. Quantitative measurement of thyroglobulin mRNA in peripheral blood of patients after total thyroidectomy. Br. J. Cancer 85 (2001) 102-106
13. Takano T., Miyauchi A., Yokozawa T., Matsuzuka F., Maeda I., Kuma K., and Amino N. Preoperative diagnosis of thyroid papillary and anaplastic carcinomas by real-time quantitative reverse transcription-polymerase chain reaction of oncofetal fibronectin messenger RNA. Cancer Res. 59 (1999) 4542-4545
14. Takano T., Ito Y., Matsuzuka F., Miya A., Kobayashi K., Yoshida H., and Miyauchi A. Quantitative measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcription factor 1 mRNAs in anaplastic thyroid carcinoma tissues and cell lines. Oncol. Rep. 18 (2007) 715-720
15. Lonigro R., Donnini D., Zappia E., Damante G., Bianchi M.E., and Guazzi S. Nestin is a neuroepithelial target gene of thyroid transcription factor-1, a homeoprotein required for forebrain organogenesis. J. Biol. Chem. 276 (2001) 47807-47813
16. Veselska R., Kuglik P., Cejpek P., Svachova H., Neradil J., Loja T., and Relichova J. Nestin expression in the cell lines derived from glioblastoma multiforme. BMC Cancer 6 (2006) 32
17. Tsujimura T., Makiishi-Shimobayashi C., Lundkvist J., Lendahl U., Nakasho K., Sugihara A., Iwasaki T., Mano M., Yamada N., Yamashita K., Toyosaka A., and Terada N. Expression of the intermediate filament nestin in gastrointestinal stromal tumors and interstitial cells of Cajal. Am. J. Pathol. 158 (2001) 817-823
18. Lobo M.V., Arenas M.I., Alonso F.J., Gomez G., Bazan E., Paino C.L., Fernandez E., Fraile B., Paniagua R., Moyano A., and Caso E. Nestin, a neuroectodermal stem cell marker molecule, is expressed in Leydig cells of the human testis and in some specific cell types from human testicular tumours. Cell Tissue Res. 316 (2004) 369-376
19. Kleeberger W., Bova G.S., Nielsen M.E., Herawi M., Chuang A.Y., Epstein J.I., and Berman D.M. Roles for the stem cell associated intermediate filament Nestin in prostate cancer migration and metastasis. Cancer Res. 67 (2007) 9199-9206
20. Wiese C., Rolletschek A., Kania G., Blyszczuk P., Tarasov K.V., Tarasova Y., Wersto R.P., Boheler K.R., and Wobus A.M. Nestin expression--a property of multi-lineage progenitor cells?. Cell Mol. Life Sci. 61 (2004) 2510-2522
21. Takano T., Ito Y., Matsuzuka F., Miya A., Kobayashi K., Yoshida H., and Miyauchi A. Expression of oncofetal fibronectin mRNA in thyroid anaplastic carcinoma. Jpn. J. Clin. Oncol. 37 (2007) 647-651
22. Takano T., Matsuzuka F., Miyauchi A., Yokozawa T., Liu G., Morita S., Kuma K., and Amino N. Restricted expression of oncofetal fibronectin mRNA in thyroid papillary and anaplastic carcinoma: an in situ hybridization study. Br. J. Cancer 78 (1998) 221-224
23. Lazzaro D., Price M., de Felice M., and Di Lauro R. The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain. Development 113 (1991) 1093-1104
24. Pelizzoli R., Tacchetti C., Luzzi P., Strangio A., Bellese G., Zappia E., and Guazzi S. TTF-1/NKX2.1 up-regulates the in vivo transcription of nestin. Int. J. Dev. Biol. 52 (2008) 55-62