Toll-like receptor 2 gene polymorphisms Arg677Trp and Arg753Gln in chronic obstructive pulmonary disease

Lung

Volumn 187, Issue 3, 2009, Pages 173-178

  Pabst, Stefan ^a   Yenice, Vildan ^a   Lennarz, Martina ^a   Tuleta, Izabela ^a   Nickenig, Georg ^a   Gillissen, Adrian ^b   Grohé, Christian ^c  

^a UNIVERSITY OF BONN   (Germany)

^b St George Medical Centre   (Germany)

^c Evangelische Lungenklinik Berlin   (Germany)

Author keywords

Chronic obstructive pulmonary disease (COPD); Genetics; Innate immunity; Single nucleotide polymorphism (SNP); Toll like receptor 2 (TLR2)

Indexed keywords

ARGININE; GLUTAMIC ACID; TOLL LIKE RECEPTOR 2; TRYPTOPHAN;

ADULT; ALLELE; ARTICLE; CAUCASIAN; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AGED; AGED, 80 AND OVER; AMPLIFIED FRAGMENT LENGTH POLYMORPHISM ANALYSIS; CASE-CONTROL STUDIES; DISEASE PROGRESSION; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TOLL-LIKE RECEPTOR 2;

EID: 67349237062     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00408-009-9144-8     Document Type: Article

References (33)

1. E Monso A Rosell G Bonet J Manterola PJ Cardona J Ruiz J Morera 1999 Risk factors for lower airway bacterial colonization in chronic bronchitis Eur Respir J 13 338 348 (Pubitemid 29086830)
2. The COPD guidelines group of the standards of care committee of the BTS 1997 BTS guidelines for the management of chronic obstructive pulmonary disease Thorax 52 Suppl 5 S1 S28
3. SC McCloskey BD Patel SJ Hinchliffe ED Reid NJ Wareham DA Lomas 2001 Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction Am J Respir Crit Care Med 164 1419 1424 (Pubitemid 33124020)
4. PS Burge PM Calverley PW Jones S Spencer JA Anderson TK Maslen 2000 Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial BMJ 320 1297 1303 (Pubitemid 30245717)
5. S Burge JA Wedzicha 2003 COPD exacerbations: definitions and classifications Eur Respir J 21 Suppl 41 46 53 (Pubitemid 36648154)
6. GC Donaldson TA Seemungal A Bhowmilk JA Wedzicha 2002 Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease Thorax 57 847 852 (Pubitemid 35178607)
7. S Sethi K Muscarella N Evans KL Klingman BJB Grant TF Murphy 2000 Airway inflammation and etiology of acute exacerbations of chronic bronchitis Chest 118 1557 1565 (Pubitemid 32001777)
8. R Medzhitov P Preston-Hurlburt CA Janeway Jr 1997 A human homologue of the Drosophila Toll protein signals activation of adaptive immunity Nature 388 394 397 (Pubitemid 27334820)
9. DM Underhill A Ozinsky 2002 Toll-like receptors: key mediators of microbe detection Curr Opin Immunol 14 103 110 (Pubitemid 34085113)
10. N Chaudhuri SK Dower MKB Whyte I Sabroe 2005 Toll-like receptors and chronic lung disease Clin Sci 109 125 133 (Pubitemid 41117295)
11. M Pierik S Joossens K Van Steen N Van Schuerbeek R Vlietinck P Rutgeerts S Vermeire 2006 Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases Inflamm Bowel Dis 12 1 8 (Pubitemid 43032444)
12. J Texereau JD Chiche W Taylor G Choukroun B Comba JB Mira 2005 The importance of Toll-like receptor 2 polymorphisms in severe infections Clin Iinfect Dis 41 Suppl 7 S408 S415 (Pubitemid 41598297)
13. FL Rock G Hardiman JC Timans RA Kastelein JF Bazan 1998 A family of human receptors structurally related to Drosophila Toll Proc Natl Acad Sci U S A 95 588 593 (Pubitemid 28083787)
14. D Droemann T Goldmann D Branscheid R Clark K Dalhoff P Zabel E Vollmer 2003 Toll-like receptor 2 is expressed by alveolar epithelial cells type II and macrophages in the human lung Histochem Cell Biol 119 103 108 (Pubitemid 36308093)
15. TC Van der Pouw Kraan M Kucukaycan AM Bakker JM Baggen JS van der Zee MA Dentener EF Wouters CL Verweij 2002 Chronic obstructive pulmonary disease is associated with the -1055 IL-13 promoter polymorphism Genes Immun 3 436 439 (Pubitemid 41656545)
16. RC Hu YJ Xu ZX Zhang JG Xie 2003 Polymorphism of interleukin-10 gene promoter and its association with susceptibility to chronic obstructive pulmonary disease in Chinese Han people Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20 504 507 (Pubitemid 38017235)
17. S Stemmler U Arinir W Klein G Rohde S Hoffjan N Wirkus K Reinitz-Rademacher A Bufe G Schultze-Werninghaus JT Epplen 2005 Association of interleukin-8 receptor alpha polymorphisms with chronic obstructive pulmonary disease and asthma Genes Immun 6 225 230 (Pubitemid 40645566)
18. BR Celli W MacNee ATS/ERS Task Force 2004 Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper Eur Respir J 23 932 946 (Pubitemid 38807371)
19. SA Miller DD Dykes HF Polesky 1988 A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Res 16 1215
20. S Pabst G Baumgarten A Stremmel M Lennarz P Knufermann A Gillissen H Vetter C Grohe 2006 Toll-like receptor (TLR) 4 polymorphisms are associated with a chronic course of sarcoidosis Clin Exp Immunol 143 420 426
21. M Folwaczny J Glas HP Török O Limbersky C Folwaczny 2004 Toll-like receptor (TLR) 2 and 4 mutations in periodontal disease Clin Exp Immunol 135 330 335 (Pubitemid 38177975)
22. PD Sasieni 2997 From genotypes to genes: doubling the sample size Biometrics 53 1253 1261 (Pubitemid 28013569)
23. PY Bochud TR Hawn A Aderem 2003 Cutting edge: A Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signalling J Immunol 170 3451 3454 (Pubitemid 36359209)
24. TJ Kang GT Chae 2001 Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients FEMS Immunol Med Microbiol 31 53 58 (Pubitemid 32722000)
25. M Ben-Ali MR Barbouche S Bousnina A Chabbou K Dellgi 2004 Toll-like receptor 2 Arg677Trp polymorphism is associated with susceptibility to tuberculosis in Tunisian patients Clin Diagn Lab Immunol 11 625 626 (Pubitemid 38661434)
26. D Malhotra V Relhan BSN Reddy R Bamezai 2005 TLR2 Arg677Trp polymorphism in leprosy: revisited Hum Genet 116 413 415 (Pubitemid 40521120)
27. NWJ Schroeder C Hermann L Hamann UB Goebel T Hartung RR Schuhmann 2003 High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR J Mol Med 81 368 372 (Pubitemid 36783241)
28. AC Ogus B Yoldas T Ozdemir A Uguz S Olcen I Keser M Coskun A Cilli O Yegin 2004 The Arg753Gln polymorphism of the human Toll-like receptor 2 gene in tuberculosis disease Eur Respir J 23 219 223 (Pubitemid 38195506)
29. NW Schroder I Diterich A Zinke J Eckert C Draing V von Baehr D Hassler S Priem K Hahn KS Michelsen T Hartung GR Burmester UB Gobel C Hermann RR Schumann 2005 Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease J Immunol 175 2534 2540 (Pubitemid 41113865)
30. CE Moore S Segal AR Berendt AVS Hill NPJ Day 2004 Lack of association between Toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureus Clin Diagn Lab Immunol 11 1194 1197 (Pubitemid 39540867)
31. R Ugenskiene M Sanak R Sakalauskas A Szczeklik 2005 Genetic polymorphisms in chronic obstructive pulmonary disease Medicina (Kaunas) 41 17 22
32. J Pons J Sauleda V Regueiro C Santos M Lopez J Ferrer AG Agusti JA Bengoechea 2006 Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease Respir Res 7 64
33. T Shuto A Imasato H Jono A Sakai H Xu T Watanabe DD Rixter H Kai A Andalibi F Linthicum YL Guan J Han AC Cato DJ Lim S Akira JD Li 2002 Glucocorticoids synergistically enhance non-typeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase J Biol Chem 277 17263 17270