Systemic inflammatory responses in dogs experimentally infected with Babesia canis; a haematological study

Veterinary Parasitology

Volumn 162, Issue 1-2, 2009, Pages 7-15

  Schetters, Th P M ^a,b   Kleuskens, J A G M ^a   Van De Crommert, J ^a   De Leeuw, P W J ^a   Finizio, A L ^b   Gorenflot, A ^b  

^a Intervet/Schering Plough Animal Health ^*  (Netherlands)

^b UNIV MONTPELLIER   (France)

Author keywords

Babesia canis; Creatinin; Dogs; Hypotension; Pathology; Shock

Indexed keywords

C REACTIVE PROTEIN; CARBESIA; CREATININE; FIBRINOGEN; IMIDOCARB DIPROPIONATE; UNCLASSIFIED DRUG;

ACUTE PHASE RESPONSE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BABESIA; BABESIOSIS; BLOOD CLOTTING TIME; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; ERYTHROCYTE; EXPERIMENTAL DOG; FEMALE; FEVER; FIBRINOGEN BLOOD LEVEL; HEMATOCRIT; HEMATOLOGY; HYPOTENSION; LEUKOPENIA; MALE; NONHUMAN; PARASITE IDENTIFICATION; PATHOGENESIS; PLASMA VOLUME; PROTEIN BLOOD LEVEL; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THROMBOCYTOPENIA;

ANIMALS; BABESIA; BABESIOSIS; BLOOD CELL COUNT; BLOOD CHEMICAL ANALYSIS; BLOOD PLATELETS; BLOOD PRESSURE; BODY TEMPERATURE; DOG DISEASES; DOGS; FEMALE; MALE; PARASITEMIA;

BABESIA CANIS; CANIS FAMILIARIS;

EID: 67349229227     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetpar.2009.02.012     Document Type: Article

References (32)

1. Baric Rafaj R., Mrljak V., Guelfi J.F., Marinculic A., Potocnjak D., Zvorc Z., and Kučer N. Nombre de plaquettes et volume moyen plaquettaire dans la bábesiose du chien. Rev. Med. Vet. 156 (2005) 95-98
2. Bo{combining double acute accent}hm M., Leisewitz A.L., Thompson P., and Schoeman J.P. Central and peripheral Babesia canis rossi parasitaemias and their association with outcome of infection. Vet. Parasitol. 141 (2006) 18-29
3. Bourdoiseau G. Canine babesiosis in France. Vet. Parasitol. 138 (2006) 118-125
4. Freeman M.J., Kirby B.M., Panciera D.L., Henik R.A., Rosin E., and Sullivan L.J. Hypotensive shock syndrome associated with acute Babesia canis infection in a dog. J. Am. Vet. Med. Assoc. 204 (1994) 94-96
5. Furlanello T., Fiorio F., Caldin M., Lubas G., and Solano-Gallego L. Clinicopathological findings in naturally occurring cases of babesiosis caused by large Babesia from dogs of northeastern Italy. Vet. Parasitol. 134 (2005) 77-85
6. Hoffmann R. Syndrome disseminierter intravasaler Geriennung (Verbrauchscoagulopathie) bei Haustieren. Fortschr. Veterinarmed. 24 (1976) 1-11
7. Jacobson L.S., Lobetti R.G., and Vaughan-Scott T. Blood pressure changes in dogs with babesiosis. J. S. Afr. Vet. Assoc. 71 (2000) 14-20
8. Jacobson L. The South African form of severe and complicated canine babesiosis: clinical advances 1994-2004. Vet. Parasitol. 138 (2006) 126-139
9. Kettner F., Reyers F., and Miller D. Thrombocytopaenia in canine babesiosis and its clinical usefulness. J. S. Afr. Vet. Assoc. 74 (2003) 63-68
10. Kwiatkowski D. Tumour necrosis factor, fever and fatality in falciparum malaria. Immunol. Lett. 25 (1990) 213-216
11. Máthé A., Vörös K., Papp L., and Reiczigel J. Clinical manifestations of canine babesiosis in Hungary (63 cases). Acta Vet. Hung. 54 (2006) 367-385
12. Matijatko V., Mrljak V., Kiš I., Kučer N., Foršek J., Živičnjak T., Romić Z., Šimec Z., and Ceron J.J. Evidence of an acute phase response in dogs naturally infected with Babesia canis. Vet. Parasitol. 144 (2007) 242-250
13. Milczak A., Riha T., Abramowicz B., and Madej E. Hemostatic disorders during the course of canine babesiosis. Med. Weter. 60 (2004) 1067-1070
14. Page I.H., and McCubbin J.W. The variable arterial pressure response to serotonin in laboratory animals and man. Circ. Res. 1 (1953) 354-362
15. Pagès J.P., Vidor E., Trouillet J.L., Bissuel G., Lecoidre O., and Moreau Y. Description clinique, hématologique et sérologique de 133 cas de babésiose canine. Prat. Méd. Chir. An. Comp. 21 (1986) 389-397
16. Reyers F., Leisewitz A.L., Lobetti R.G., Milner R.J., and Jacobson L.S. Canine babesiosis in South Africa: more than one disease. Does this serve as a model for falciparum malaria?. Ann. Trop. Med. Parasitol. 92 (1998) 503-511
17. Ruiz de Gopegui R., Penalba B., Goicoa A., Espada Y., Fidalgo L.E., and Espino L. Clinico-pathological findings and coagulation disorders in 45 cases of canine babesiosis in Spain. Vet. J. 174 (2007) 129-132
18. Schetters Th.P.M., Kleuskens J.A.G.M., Scholtes N.C., Pasman J.W., and Bos H.J. Vaccination of dogs against Babesia canis infection using antigen from culture supernatant with an emphasis on clinical babesiosis. Vet. Parasitol. 52 (1994) 219-233
19. Schetters Th., Kleuskens J., Scholtes N., and Bos H.J. Strain variation limits protective activity of vaccines based on soluble Babesia canis antigens. Parasite Immunol. 17 (1995) 215-218
20. Schetters Th.P.M., Scholtes N.C., Kleuskens J.A.G.M., and Bos H.J. Not peripheral parasitaemia but the level of soluble parasite antigen in plasma correlates with vaccine efficacy against Babesia canis. Parasite Immunol. 18 (1996) 1-6
21. Schetters Th., Kleuskens J., Scholtes N., Moubry K., and Gorenflot A. Different Babesia canis isolates, different diseases. Parasitology 115 (1997) 485-493
22. Schetters Th.P.M., Kleuskens J.A.G.M., Scholtes N.C., Goovaerts D., Pasman J., and Bos H.J. Vaccination of dogs against Babesia canis. Vet. Parasitol. 73 (1997) 35-41
23. Schetters Th.P.M., Kleuskens J.A.G.M., Scholtes N.C., and Goovaerts D. Parasite localisation and dissemination in the Babesia-infected host. Ann. Trop. Med. Parasitol. 92 (1998) 513-519
24. Schoeman J.P., Rees P., and Herrtage M.E. Endocrine predictors of mortality in canine babesiosis caused by Babesia canis rossi. Vet. Parasitol. 148 (2007) 75-82
25. Sethi A.K., Sharma P., Mohta M., and Tyagi A. Shock-a short review. Indian J. Anaesth. 47 (2003) 345-359
26. Solano-Gallego L., Trotta M., Carli E., Carcy B., Caldin M., and Furlanello T. Babesia canis canis and Babesia canis vogeli clinicopathological findings and DNA detection by means of PCR-RFLP in blood from Italian dogs suspected of tick-borne disease. Vet. Parasitol. 157 (2008) 211-221
27. Ulutas B., Barramli G., Ulutas P.A., and Karagenc T. Serum concentration of some acute phase proteins in naturally occurring canine babesiosis: a preliminary study. Vet. Clin. Pathol. 34 (2005) 144-147
28. Vercammen F., De Deken R., and Maes L. Haematological and biochemical profile in experimental canine babesiosis (Babesia canis). Vlaams Diergeneeskundig Tijdschrift 66 (1997) 174-178
29. Wiggins R.C., Glatfelter A., Campbell A.M., Kunkel R.G., and Ulevitch R.J. Acute hypotension due to platelet serotonin-induced chemorelaxes after intravenous injection of dextran sulfate in the rabbit. Circ. Res. 57 (1985) 262-277
30. Wijesekera S.K., Carter R., Rathnayaka L., and Mendis K.N. A malaria parasite toxin associated with Plasmodium vivax paroxysms. Clin. Exp. Immunol. 104 (1996) 221-227
31. Wright I.G., and Goodger B.V. Pathogenesis of babesiosis. In: Ristic M. (Ed). Babesiosis of Domestic Animals and Man (1988), CRC Press, Inc., Boca Raton, FL 99-118
32. Zygner W., Gójska O., Rapacka G., Jaros D., and Wedrychowicz H. Hematological changes during the course of canine babesiosis by large Babesia in domestic dogs in Warsaw (Poland). Vet. Parasitol. 145 (2007) 146-151