Low-risk human papillomavirus type 6 DNA load and integration in cervical samples from women with squamous intraepithelial lesions

Journal of Clinical Virology

Volumn 45, Issue 2, 2009, Pages 96-99

  Coutlée, François ^a,b,c   Trottier, Helen ^b   Gagnon, Simon ^a   Koushik, Anita ^b   Richardson, Harriet ^b   Roger, Michel ^a,c   Ferenczy, Alex S ^d   Franco, Eduardo L ^b  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Division of Clinical Epidemiology   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

CIN; Condyloma; HPV 6; SIL; Viral load

Indexed keywords

BETA GLOBIN; VIRUS DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER GRADING; COLPOSCOPY; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA INTEGRATION; FEMALE; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 6; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SQUAMOUS EPITHELIUM; SQUAMOUS INTRAEPITHELIAL LESION; UTERINE CERVIX CARCINOMA IN SITU; VIRUS DETECTION; VIRUS LOAD;

DNA, VIRAL; FEMALE; HUMAN PAPILLOMAVIRUS 6; HUMANS; NEOPLASMS, SQUAMOUS CELL; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS INFECTIONS; POLYMERASE CHAIN REACTION; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS; VIRUS INTEGRATION;

EID: 67349216234     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2009.03.019     Document Type: Article

References (14)

1. The ALTS Group. Human papillomavirus testing for triage of women with cytologic evidence of low-grade squamous intraepithelial lesions: baseline data from a randomized trial. J Natl Cancer Inst 92 (2000) 397-402
2. Greer C.E., Wheeler C.M., Ladner M.B., Beutner K., Coyne M.Y., Liang H., et al. Human papillomavirus (HPV) type distribution and serological response to HPV type 6 virus-like particles in patients with genital warts. J Clin Microbiol 33 (1995) 2058-2063
3. Brown D.R., Bryan J.T., Cramer H., and Fife K.H. Analysis of human papillomavirus types in exophytic condylomata acuminata by hybrid capture and Southern blot techniques. J Clin Microbiol 31 (1993) 2667-2673
4. Clifford G.M., Rana R.K., Franceschi S., Smith J.S., Gough G., and Pimenta J.M. Human papillomavirus genotype distribution in low-grade cervical lesions: comparison by geographic region and with cervical cancer. Cancer Epidemiol Biomarkers Prev 14 (2005) 1157-1164
5. Wang S.S., and Hildesheim A. Viral and host factors in human papillomavirus persistence and progression. J Natl Cancer Inst Monogr (2003) 35-40
6. Koushik A., Ghosh A., Duarte-Franco E., Forest P., Voyer H., Matlashewski G., et al. The p53 codon 72 polymorphism and risk of high-grade cervical intraepithelial neoplasia. Cancer Det Prev 29 (2005) 307-316
7. Richardson H., Kelsall G., Tellier P., Voyer H., Abrahamowicz M., Coutlée F., et al. The natural history of type-specific HPV infections in female university students. Cancer Epidemiol Biom Prev 12 (2003) 485-490
8. Khouadri S., Villa L.L., Gagnon S., Koushik A., Richardson H., Ferenczy A., et al. Viral load of episomal and integrated forms of Human papillomavirus type 33 in high-grade squamous intraepithelial lesions of the uterine cervix. Int J Cancer 121 (2007) 2674-2681
9. Thorland E.C., Myers S.L., Persing D.H., Sarkar G., McGovern R.M., Gostout B.S., et al. Human papillomavirus type 16 integrations in cervical tumors frequently occur in common fragile sites. Cancer Res 60 (2000) 5916-5921
10. Flores R., Papenfuss M., Klimecki W.T., and Giuliano A.R. Cross-sectional analysis of oncogenic HPV viral load and cervical intraepithelial neoplasia. Int J Cancer 118 (2006) 1187-1193
11. Cheung J.L., Lo K.W., Cheung T.H., Tang J.W., and Chan P.K. Viral load, E2 gene disruption status, and lineage of human papillomavirus type 16 infection in cervical neoplasia. J Infect Dis 194 (2006) 1706-1712
12. McKay S.P., Gregoire L., Lonardo F., Reidy P., Mathog R.H., and Lancaster W.D. Human papillomavirus (HPV) transcripts in malignant inverted papilloma are from integrated HPV DNA. Laryngoscope 115 (2005) 1428-1431
13. Reidy P.M., Dedo H.H., Rabah R., Field J.B., Mathog R.H., Gregoire L., et al. Integration of human papillomavirus type 11 in recurrent respiratory papilloma-associated cancer. Laryngoscope 114 (2004) 1906-1909
14. Longworth M.S., and Laimins L.A. Pathogenesis of human papillomaviruses in differentiating epithelia. Microbiol Mol Biol Rev 68 (2004) 362-372