A new ginsenosidase from Aspergillus strain hydrolyzing 20-O-multi-glycoside of PPD ginsenoside

Process Biochemistry

Volumn 44, Issue 7, 2009, Pages 772-775

  Yu, Hongshan ^a   Liu, Qingmei ^b   Zhang, Chunzhi ^a   Lu, Mingchun ^a   Fu, Yaoyao ^a   Im, Wan Taek ^b   Lee, Sung Taik ^b   Jin, Fengxie ^a  

^a DALIAN POLYTECHNIC UNIVERSITY   (China)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Ginsenosidase type II; Hydrolysis of 20 O multi glycoside of ginsenosides; PPD ginsenoside

Indexed keywords

ASPERGILLUS STRAINS; GINSENOSIDASE TYPE II; GINSENOSIDE RE; GINSENOSIDE-RD; GLYCOSIDASES; O-GLYCOSIDES; PPD GINSENOSIDE;

HYDROLYSIS; RUBIDIUM; SUGARS;

PHARMACODYNAMICS;

ASPERGILLUS;

EID: 67349209884     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2009.02.005     Document Type: Article

References (21)

1. In: Wang T.S. (Ed). China ginseng (2001), Laoning Science and Publishing House, Shenyang of China p671-p695
2. Yu H.S., Zhang C.Z., Liu M.C., Sun F., Fu Y.Y., and Jin F.X. Purification and characterization of ginsenosidase hydrolyzing multi-glycosides of protopanaxadiol ginsenoside, Ginsenoside Type I. Chem Pharm Bull 55 (2007) 231-235
3. 2. Int J Biochem Cell Biol 30 (1998) 327-338
4. 3. Jpn J Cancer Res 87 (1996) 357-362
5. Bae E.A., Han M.J., Choo M.K., Park S.Y., and Kim D.H. Metabolism of 20(S)-and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitrobiological activities. Biol Pharm Bull 25 (2002) 58-63
6. 3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase. Br J Pharmacol 140 (2003) 661-670
7. Lee B.H., Lee S.J., Hui J.H., Lee S., Sung J.H., Huh J.D., et al. In vitro antigen toxic activity of novel ginseng saponin metabolites formed by intestinal bacteria. Planta Med 64 (1998) 500-503
8. Kanaoka M., Akao T., and Kobashi K. Metabolism of ginseng saponins, glycosides, by human intestinal flora. J Tradit Med 11 (1994) 241-245
9. 2 from human intestinal bacteria. Biol Pharm Bull 23 (2000) 1481-1485
10. 3 by Microbacterium sp. GS514. Phytochemistry 69 (2008) 218-224
11. Zhong J.J., and Yue C.J. Plant cells: secondary metabolite heterogeneity and its manipulation. Adv Biochem Eng/Biotechnol 100 (2005) 53-88
12. Yue C.J., and Zhong J.J. Purification and characterization of UDPG:ginsenoside Rd glucosyltransferase from suspended cells of Panax notoginseng. Process Biochem 40 (2005) 3742-3748
13. Yue C.J., Zhou X., and Zhong J.J. Protopanaxadiol 6-hydroxylase and its role in regulating the ginsenoside heterogeneity in Panax notoginseng cells. Biotechnol Bioeng 100 (2008) 933-940
14. Yu H.S., Wu S.J., Guo Y., and Jin F.X. Purification and characterization of gisenoside β-glucosidase. J Ginseng Res 23 (1999) 50-54
15. Zhang C.Z., Yu H.S., Bao Y.M., An L.J., and Jin F.X. Purification and characterization of ginsenoside-β-glucosidase from ginseng. Chem Pharm Bull 49 (2001) 795-798
16. Yu H.S., Gong J.M., Zhang C.Z., and Jin F.X. Purification and characterization of ginsenoside-α-rhamnosidase. Chem Pharm Bull 50 (2002) 175-178
17. Zhang C.Z., Yu H.S., Bao Y.M., An L.J., and Jin F.X. Purification and characterization of gisenoside-α-arabiofuranase hydrolyzing ginseoside Rc into Rd from the fresh rood of Panax ginseng. Process Biochem 37 (2002) 793-798
18. Yu H.S., Liu H., Zhang C.Z., Tan D., Lu M.C., and Jin F.X. Purification and characterization of gypenoside-α-L-rhamnosidase hydrolyzing gypenoside-5 into gisenoside Rd. Process Biochem 39 (2004) 861-867
19. Jin F.X., Cheng X.M., Shi Y.F., and Zhang C.Z. Isolation of New thermophilic aerobic bacteria which produce thermostable α-amylase. J Gen Appl Microbiol 36 (1992) 415-424
20. In: Li J.W. (Ed). Methods for biochemistry, Shengwu-huaxue Shiyan-yuanli he Fangfa in Chinese (1997), Beijing University Press 189-196
21. In: Li J.W. (Ed). Methods for biochemistry, Shengwu-huaxue Shiyan-yuanli he Fangfa in Chinese (1997), Beijing University Press 82-100