Comparative assessing for radiological, chemical, and physical exposures at the French uranium conversion plant: Is uranium the only stressor?

International Journal of Hygiene and Environmental Health

Volumn 212, Issue 4, 2009, Pages 398-413

  Guseva Canu, Irina ^a   Paquet, François ^a   Goldberg, Marcel ^b   Auriol, Bernard ^c   Bérard, Philippe ^d   Collomb, Philippe ^c   David, Jean Claude ^c   Molina, Gilbert ^c   Perez, Partice ^c   Tirmarche, Margot ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

^b INSERM   (France)

^c AREVA NP   (France)

^d DIF   (France)

Author keywords

Chemicals; Exposure assessment; Internal contamination; Job exposure matrix; Nuclear industry; Uranium

Indexed keywords

EID: 67349206422     PISSN: 14384639     EISSN: 1618131X     Source Type: Journal    
DOI: 10.1016/j.ijheh.2008.09.002     Document Type: Article

References (43)

1. Ansoborlo E., Chazel V., Houpert P., Henge-Napoli M.H., Paquet F., Hodgson A., et al. Assessment of physico-chemical and biokinetic properties of uranium peroxide hydrate UO4. Health Phys. 75 4 (1998) 389-397
2. Ansoborlo E., Chazel V., Henge-Napoli M.H., Pihet P., Rannou A., Bailey M.R., et al. Determination of the physical and chemical properties, biokinetics, and dose coefficients of uranium compounds handled during nuclear fuel fabrication in France. Health Phys. 82 3 (2002) 279-289
3. Benke G., Sim M., Fritschi L., and Aldred G. Beyond the job exposure matrix (JEM): the task exposure matrix (TEM). Ann. Occup. Hyg. 44 6 (2000) 475-482
4. Boice Jr. J.D., Marano D.E., Cohen S.S., Mumma M.T., Blot W.J., Brill A.B., et al. Mortality among Rocketdyne workers who tested rocket engines, 1948-1999. J. Occup. Environ. Med. 48 10 (2006) 1070-1092
5. Britcher A.R., and Strong R. Personal air sampling - a technique for the assessment of chronic low level exposure?. Radiat. Protect. Dosim. 53 1-4 (1994) 59-63
6. Cardis E., Vrijheid M., Blettner M., Gilbert E., Hakama M., Hill C., et al. Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries. Br. Med. J. 331 7508 (2005) 77-80
7. Cardis E., Vrijheid M., Blettner M., Gilbert E., Hakama M., Hill C., et al. The 15-country collaborative study of cancer risk among radiation workers in the nuclear industry: estimates of radiation-related cancer risks. Radiat. Res. 167 4 (2007) 396-416
8. Carpenter A.V., Flanders W.D., Frome E.L., Crawford-Brown D.J., and Fry S.A. CNS cancers and radiation exposure: a case-control study among workers at two nuclear facilities. J. Occup. Med. 29 7 (1987) 601-604
9. Carpenter A.V., Flanders W.D., Frome E.L., Tankersley W.G., and Fry S.A. Chemical exposures and central nervous system cancers: a case-control study among workers at two nuclear facilities. Am. J. Ind. Med. 13 3 (1988) 351-362
10. Chazel V., Houpert P., Paquet F., and Ansoborlo E. Effect of absorption parameters on calculation of the dose coefficient: example of classification of industrial uranium compounds. Radiat. Protect. Dosim. 94 3 (2001) 261-268
11. Cohen J. Statistical Power Analyses for the Behavioral Sciences (1988), Lawrence Erlbaum Associates, Hillsdale, NJ
12. EC, 1998. Council of the European Union. COUNCIL DIRECTIVE 98/24/EC of 7 April 1998 on the protection of the health and safety of workers from the risk related to chemical agents at work (fourteenth individual Directive within the meaning of Article 16(1) of Directive 89/391/EEC). OJ L131, 11-23.
13. EC, 2004. Parliament and Council of the European Union. DIRECTIVE 2004/37/EC of 29 April 2004 on the protection of workers from the risk related to exposure to carcinogens or mutagens at work (sixth individual Directive within the meaning of Article 16(1) of Directive 89/391/EEC) (codified version). OJ L229, 23-34.
14. EC, 2006. Council of the European Union. REGULATION (EC) No. 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the registration, evaluation, authorisation and restriction of chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No. 793/93 and Commission Regulation (EC) No. 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. OJ L396, 1-394.
15. Eheman C.R., and Tolbert P.E. Estimating occupational radiation doses when individual dosimetry information is not available: a job exposure matrix. Am. J. Ind. Med. 36 3 (1999) 348-359
16. Fleiss J.L. Statistical Methods for Rates and Proportions. second ed. (1981), Wiley, New York
17. Goldberg M., Kromhout H., Guenel P., Fletcher A.C., Gerin M., Glass D.C., et al. Job exposure matrices in industry. Int. J. Epidemiol. 22 Suppl. 2 (1993) S10-S15
18. Guseva Canu I., Ellis E.D., and Tirmarche M. Cancer risk in nuclear workers occupationally exposed to uranium - emphasis on internal exposure. Health Phys. 94 1 (2008) 1-17
19. Guseva Canu I., Molina G., Goldberg M., Collomb P., David J.C., Perez P., et al. Development of a job exposure matrix for the epidemiological follow-up of workers in the French nuclear industry. Rev. Epidemiol. Sante Publ. 56 1 (2008) 21-29
20. Guseva Canu I., Rogel A., Samson E., Benhamou S., Laplanche A., and Tirmarche M. Cancer mortality risk among biology research workers in France: first results of two retrospective cohorts studies. Int. Arch. Occup. Environ. Health 81 6 (2008) 777-785
21. Henn S.A., Utterback D.F., Waters K.M., Markey A.M., and Tankersley W.G. Task- and time-dependent weighting factors in a retrospective exposure assessment of chemical laboratory workers. J. Occup. Environ. Hyg. 4 2 (2007) 71-79
22. Hoar S. Job exposure matrix methodology. J. Toxicol. - Clin. Toxicol. 21 1-2 (1983) 9-26
23. International Commission on Radiological Protection (ICRP). Human Respiratory Tract Model for Radiological Protection (1994), Pergamon Press, Oxford
24. Kauppinen T., Toikkanen J., and Pukkala E. From cross-tabulations to multipurpose exposure information systems: a new job-exposure matrix. Am. J. Ind. Med. 33 4 (1998) 409-417
25. Kauppinen T.P. Assessment of exposure in occupational epidemiology. Scand. J. Work Environ. Health 20 special issue (1994) 19-29
26. Krishnadasan A., Kennedy N., Zhao Y., Morgenstern H., and Ritz B. Nested case-control study of occupational chemical exposures and prostate cancer in aerospace and radiation workers. Am. J. Ind. Med. 50 5 (2007) 383-390
27. Krishnadasan A., Kennedy N., Zhao Y., Morgenstern H., and Ritz B. Nested case-control study of occupational physical activity and prostate cancer among workers using a job exposure matrix. Cancer Causes Control 19 1 (2008) 107-114
28. Landis J.R., and Koch G.G. The measurement of observer agreement for categorical data. Biometrics 33 (1977) 159-174
29. Last J.M. A Dictionary of Epidemiology (1995), Oxford University Press, Oxford
30. Marquart H., Northage C., and Money C. Exposure scenarios for workers. J. Exposure Sci. Environ. Epidemiol. 17 Suppl. 1 (2007) S16-25
31. Ritz B. Cancer mortality among workers exposed to chemicals during uranium processing. J. Occup. Environ. Med. 41 7 (1999) 556-566
32. Ritz B., Morgenstern H., Froines J., and Moncau J. Chemical exposures of rocket-engine test-stand personnel and cancer mortality in a cohort of aerospace workers. J. Occup. Environ. Med. 41 10 (1999) 903-910
33. Ritz B., Morgenstern H., Crawford-Brown D., and Young B. The effects of internal radiation exposure on cancer mortality in nuclear workers at Rocketdyne/Atomics International. Environ. Health Perspect. 108 8 (2000) 743-751
34. Ritz B., Zhao Y., Krishnadasan A., Kennedy N., and Morgenstern H. Estimated effects of hydrazine exposure on cancer incidence and mortality in aerospace workers. Epidemiology 17 2 (2006) 154-161
35. Rogel A., Carre N., Amoros E., Bonnet-Belfais M., Goldberg M., Imbernon E., et al. Mortality of workers exposed to ionizing radiation at the French National Electricity Company. Am. J. Ind. Med. 47 1 (2005) 72-82
36. Rooney C., Beral V., Maconochie N., Fraser P., and Davies G. Case-control study of prostatic cancer in employees of the United Kingdom Atomic Energy Authority. BMJ 307 6916 (1993) 1391-1397
37. Ruttenber A.J., McCrea J.S., Wade T.D., Schonbeck M.F., LaMontagne A.D., Van Dyke M.V., et al. Integrating workplace exposure databases for occupational medicine services and epidemiologic studies at a former nuclear weapons facility. Appl. Occup. Environ. Hyg. 16 2 (2001) 192-200
38. Ruttenber A.J., Schonbeck M., McCrea J., McClure D., and Martyny J. Improving estimates of exposures for epidemiologic studies of plutonium workers. Occup. Med. 16 2 (2001) 239-258
39. Spearman C. The proof and measurement of association between two things. Am. J. Psychol. 15 (1904) 72-101
40. Telle-Lamberton M., Bergot D., Gagneau M., Samson E., Giraud J.M., Neron M.O., et al. Cancer mortality among French Atomic Energy Commission workers. Am. J. Ind. Med. 45 1 (2004) 34-44
41. Telle-Lamberton M., Samson E., Caer S., Bergot D., Bard D., Bermann F., et al. External radiation exposure and mortality in a cohort of French nuclear workers. Occup. Environ. Med. 64 10 (2007) 694-700
42. Vrijheid M., Cardis E., Ashmore P., Auvinen A., Bae J.M., Engels H., et al. Mortality from diseases other than cancer following low doses of ionizing radiation: results from the 15-Country Study of nuclear industry workers. Int. J. Epidemiol. 36 5 (2007) 1126-1135
43. Wing S., Shy C.M., Wood J.L., Wolf S., Cragle D.L., Tankersley W., et al. Job factors, radiation and cancer mortality at Oak Ridge National Laboratory: follow-up through 1984. Am. J. Ind. Med. 23 2 (1993) 265-279