Successful treatment of relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia with T315I mutation after haplo-identical hematopoietic stem cell transplantation with donor lymphocyte transfusion and interferon-α-2b

Leukemia Research

Volumn 33, Issue 8, 2009, Pages

  Wang, Ying ^a   Xue, Meng Xing ^a   Wu, Xiao Hui ^a   Tang, Xiao Wen ^a   Sun, Ai Ning ^a   Wu, De Pei ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2B INTERFERON; ASPARAGINASE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; CYTARABINE; DEXAMETHASONE; EPIRUBICIN; GRANULOCYTE COLONY STIMULATING FACTOR; IMATINIB; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; THYMOCYTE ANTIBODY; VINDESINE;

ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; BONE MARROW EXAMINATION; CASE REPORT; DONOR LYMPHOCYTE INFUSION; DRUG WITHDRAWAL; FATIGUE; FEVER; FOLLOW UP; GRAFT VERSUS HOST REACTION; HAPLOIDY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; LETTER; LEUKEMIA; LOW DRUG DOSE; LYMPHATIC LEUKEMIA; LYMPHOCYTE TRANSFUSION; MALE; PHILADELPHIA 1 CHROMOSOME; PHILADELPHIA CHROMOSOME POSITIVE CELL; PRIORITY JOURNAL; RADIATION DOSE; REMISSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; AMINO ACID SUBSTITUTION; ANTINEOPLASTIC AGENTS; FUSION PROTEINS, BCR-ABL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INTERFERON ALFA-2B; MALE; MUTATION, MISSENSE; PHILADELPHIA CHROMOSOME; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECURRENCE; REMISSION INDUCTION; TRANSPLANTATION, HOMOLOGOUS;

EID: 67349205595     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.02.020     Document Type: Letter

References (21)

1. Ottmann O.G., and Wassmann B. Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia. Hematol Am Soc Hematol Educ Program (2005) 118-122
2. Abou Mourad Y.R., Fernandez H.F., and Kharfan-Dabaja M.A. Allogeneic hematopoietic cell transplantation for adult Philadelphia-positive acute lymphoblastic leukemia in the era of tyrosine kinase inhibitors. Biol Blood Marrow Transplant 14 (2008) 949-958
3. Piccaluga P.P., Paolini S., and Martinelli G. Tyrosine kinase inhibitors for the treatment of Philadelphia chromosome-positive adult acute lymphoblastic leukemia. Cancer 110 (2007) 1178-1186
4. Collins Jr. R.H., Shpilberg O., Drobyshi W.R., et al. Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation. J Clin Oncol 15 (1997) 433-444
5. Collins Jr. R.H., Goldstein S., Giralt S., et al. Donor leukocyte infusions in acute lymphocytic leukemia. Bone Marrow Transplant 26 (2000) 511-516
6. Loren A.W., and Porter D.L. Donor leukocyte infusions for the treatment of relapsed acute leukemia after allogeneic stem cell transplantation. Bone Marrow Transplant 41 (2008) 483-493
7. Nagafuji K., Harada N., Eto T., et al. Interferon-alpha treatment of acute lymphoblastic leukemia relapse after unrelated bone marrow transplantation. Int J Hematol 67 (1998) 63-68
8. Sumi M., Ichikawa N., Shimizu I., et al. Successful treatment with interferon-alpha-2b and imatinib in an adult Japanese male with Philadelphia chromosome-positive acute lymphoblastic leukemia and minimal residual disease following allogeneic transplantation. Bone Marrow Transplant 41 (2008) 827-829
9. Arellano M.L., Langston A., Winton E., et al. Treatment of relapsed acute leukemia after allogeneic transplantation: a single center experience. Biol Blood Marrow Transplant 13 (2007) 116-123
10. Wassmann B., Pfeifer H., Stadler M., et al. Early molecular response to posttransplantation imatinib determines outcome in MRD+ Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). Blood 106 (2005) 458-463
11. Yoshimitsu M., Fujiwara H., Ozaki A., et al. Case of a patient with Philadelphia-chromosome-positive acute lymphoblastic leukemia relapsed after myeloablative allogeneic hematopoietic stem cell transplantation treated successfully with imatinib and sequential donor lymphocyte infusions. Int J Hematol 88 (2008) 331-335
12. Tiribelli M., Sperotto A., Candoni A., et al. Nilotinib and donor lymphocyte infusion in the treatment of Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) relapsing after allogeneic stem cell transplantation and resistant to imatinib. Leuk Res 33 (2009) 174-177
13. Ottmann O., Dombret H., Martinelli G., et al. Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a phase 2 study. Blood 110 (2007) 2309-2315
14. Giles F.J., Cortes J., Jones D., et al. MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation. Blood 109 (2007) 500-502
15. Huang X.J., Liu D.H., Liu K.Y., et al. Donor lymphocyte infusion for the treatment of leukemia relapse after HLA-mismatched/haploidentical T-cell-replete hematopoietic stem cell transplantation. Hematologica 92 (2007) 414-417
16. Choi S.J., Lee J.H., Lee J.H., et al. Treatment of relapsed acute lymphoblastic leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a prospective study. Bone Marrow Transplant 36 (2005) 163-169
17. Posthuma E.F., Marijt E.W., Barge R.M., et al. Alpha-interferon with very-low-dose donor lymphocyte infusion for hematologic or cytogenetic relapse of chronic myeloid leukemia induces rapid and durable complete remissions and is associated with acceptable graft-versus-host disease. Biol Blood Marrow Transplant 10 (2004) 204-212
18. Kolb H.J. Graft-versus-leukemia effects of transplantation and donor lymphocytes. Blood 112 (2008) 4371-4383
19. Grigg A., Kannan K., Schwarer A.P., et al. Chemotherapy and granulocyte colony stimulating factor-mobilized blood cell infusion followed by interferon-alpha for relapsed malignancy after allogeneic bone marrow transplantation. Intern Med J 31 (2001) 15-22
20. Jedema I., Barge R.M., Willemze R., et al. High susceptibility of human leukemic cells to Fas-induced apoptosis is restricted to G1 phase of the cell cycle and can be increased by interferon treatment. Leukemia 17 (2003) 576-584
21. Samson D., Volin L., Schanz U., et al. Feasibility and toxicity of interferon maintenance therapy after allogeneic BMT for multiple myeloma: a pilot study of the EBMT. Bone Marrow Transplant 17 (1996) 759-762