Reduced ability of hemagglutinin of the CAM-70 measles virus vaccine strain to use receptors CD46 and SLAM

Vaccine

Volumn 27, Issue 29, 2009, Pages 3838-3848

  Kato, Seiichi ^a   Ohgimoto, Shinji ^a   Sharma, Luna Bhatta ^a   Kurazono, Sekiko ^a   Ayata, Minoru ^a   Komase, Katsuhiro ^b   Takeda, Makoto ^c   Takeuchi, Kaoru ^d   Ihara, Toshiaki ^e   Ogura, Hisashi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

^e MIE NATIONAL HOSPITAL   (Japan)

Author keywords

Cell fusion; Hemagglutinin; Measles virus

Indexed keywords

CD150 ANTIGEN; MEASLES VACCINE; MEMBRANE COFACTOR PROTEIN; VIRUS HEMAGGLUTININ;

ANIMAL CELL; ARTICLE; DENDRITIC CELL; H GENE; HUMAN; HUMAN CELL; MEASLES VIRUS; MEASLES VIRUS CAM 70; MONOCYTE DERIVED DENDRITIC CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIROGENESIS; VIRUS GENE; VIRUS INHIBITION; VIRUS STRAIN;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIGENS, CD; ANTIGENS, CD46; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; DENDRITIC CELLS; HELA CELLS; HEMAGGLUTININS, VIRAL; HUMANS; LYMPHOCYTES; MEASLES VIRUS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECEPTORS, VIRUS; SEQUENCE ANALYSIS, DNA; VERO CELLS; VIRUS ATTACHMENT;

EID: 67349202144     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.04.010     Document Type: Article

References (63)

1. Wolfson L.J., Strebel P.M., Gacic-Dobo M., Hoekstra E.J., McFarland J.W., and Hersh B.S. Measles initiative. Has the 2005 measles mortality reduction goal been achieved? A natural history modelling study. Lancet 369 (2007) 191-200
2. Morita Y., Suzuki T., Shiono M., Shiobara M., Saitoh M., Tsukagoshi H., et al. Sequence and phylogenetic analysis of the nucleoprotein (N) gene in measles viruses prevalent in Gunma, Japan, in 2007. Jpn J Infect Dis 60 (2007) 402-404
3. Okafuji T., Okafuji T., Fujino M., and Nakayama T. Current status of measles in Japan: molecular and seroepidemiological studies. J Infect Chemother 12 (2006) 343-348
4. Ueda S., Takahashi M., Minekawa Y., Ogino T., Suzuki N., Yamanishi K., et al. Studies on further attenuated live measles vaccine. Part I. Adaptation of measles virus to the chorioallantoic membrane of chick embryo and clinical tests on the strain. Biken J 13 (1970) 111-116
5. Ueda S., Takahashi M., Minekawa Y., Ogino T., Suzuki N., Yamanishi K., et al. Studies on further attenuated live measles vaccine. Part II. Correlation between the titer of the vaccine, the antibody response and clinical reactions. Biken J 13 (1970) 117-120
6. Okuno Y., Ueda S., Kurimura T., Suzuki N., Yamanishi K., Baba K., et al. Studies on further attenuated live measles vaccine. Part VII. Development and evaluation of CAM-70 measles virus vaccine. Biken J 14 (1971) 253-258
7. Ozaki T., Matsui Y., Kajita Y., and Nishimura N. Clinical and serological studies on CAM-70 live attenuated measles vaccine: an 18-year survey at a pediatric clinic in Japan. Vaccine 20 (2002) 2618-2622
8. Lamb R.A. Paramyxovirus fusion: a hypothesis for changes. Virology 197 (1993) 1-11
9. Dorig R.E., Marcil A., Chopra A., and Richardson C.D. The human CD46 molecule is a receptor for measles virus (Edmonston strain). Cell 75 (1993) 295-305
10. Erlenhoefer C., Wurzer W.J., Loffler S., Schneider-Schaulies S., ter Meulen V., and Schneider-Schaulies J. CD150 (SLAM) is a receptor for measles virus but is not involved in viral contact-mediated proliferation inhibition. J Virol 75 (2001) 4499-4505
11. Hsu E., Iorio C., Sarangi F., Khine A., and Richardson C. CDw150 (SLAM) is a receptor for lymphotropic strain of measles virus and may account for the immunosuppressive properties of this virus. Virology 279 (2001) 9-21
12. Naniche D., Varior-Krishnan G., Cervoni F., Wild T.F., Rossi B., Rabourdin-Combe C., et al. Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus. J Virol 67 (1993) 6025-6032
13. Tatsuo H., Ono N., Tanaka K., and Yanagi Y. SLAM (CDw150) is a cellular receptor for measles virus. Nature 406 (2000) 893-897
14. Liszewski M.K., Post T.W., and Atkinson J.P. Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster. Annu Rev Immunol 9 (1991) 431-455
15. Yanagi Y., Takeda M., and Ohno S. Measles virus: cellular receptors, tropism and pathogenesis. J Gen Virol 87 (2006) 2767-2779
16. Aversa G., Carballido J., Punnonen J., Chang C.C., Hauser T., Cocks B.G., et al. SLAM and its role in T cell activation and Th cell responses. Immunol Cell Biol 75 (1997) 202-205
17. Cocks B.G., Chang C.C., Carballido J.M., Yssel H., de Vries J.E., and Aversa G. A novel receptor involved in T-cell activation. Nature 376 (1995) 260-263
18. Sidorenko S.P., and Clark E.A. Characterization of a cell surface glycoprotein IPO-3, expressed on activated human B and T lymphocytes. J Immunol 151 (1993) 4614-4624
19. Tahara M., Takeda M., Shirogane Y., Hashiguchi T., Ohno S., and Yanagi Y. Measles virus infects both polarized epithelial and immune cells by using distinctive receptor-binding sites on its hemagglutinin. J Virol 82 (2008) 4630-4637
20. Leonard V.H., Sinn P.L., Hodge G., Miest T., Devaux P., Oezguen N., et al. Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed. J Clin Invest 118 (2008) 2448-2458
21. Takeda M. Measles virus breaks through epithelial cell barriers to achieve transmission. J Clin Invest 118 (2008) 2386-2389
22. Bartz R., Brinckmann U., Dunster L.M., Rima B., ter Meulen V., and Schneider-Schaulies J. Mapping amino acids of the measles virus hemagglutinin responsible for receptor (CD46) downregulation. Virology 224 (1996) 334-337
23. Hsu E.C., Sarangi F., Iorio C., Sidhu M.S., Udem S.A., Dillehay D.L., et al. A single amino acid change in the hemagglutinin protein of measles virus determines its ability to bind CD46 and reveals another receptor on marmoset B cells. J Virol 72 (1998) 2905-2916
24. Lecouturier V., Fayolle J., Caballero M., Carabana J., Celma M.L., Fernandez-Munoz R., et al. Identification of two amino acids in the hemagglutinin glycoprotein of measles virus (MV) that govern hemadsorption, HeLa cell fusion, and CD46 downregulation: phenotypic markers that differentiate vaccine and wild-type MV strains. J Virol 70 (1996) 4200-4204
25. Seki F., Takeda M., Minagawa H., and Yanagi Y. Recombinant wild-type measles virus containing a single N481Y substitution in its haemagglutinin cannot use receptor CD46 as efficiently as that having the haemagglutinin of the Edmonston laboratory strain. J Gen Virol 87 (2006) 1643-1648
26. Xie M.F., Tanaka K., Ono N., Minagawa H., and Yanagi Y. Amino acid substitutions at position 481 differently affect the ability of the measles virus hemagglutinin to induce cell fusion in monkey and marmoset cells co-expressing the fusion protein. Arch Virol 144 (1999) 1689-1699
27. Patterson J.B., Scheiflinger F., Manchester M., Yilma T., and Oldstone M.B. Structural and functional studies of the measles virus hemagglutinin: identification of a novel site required for CD46 interaction. Virology 256 (1999) 142-151
28. Buckland R. Molecular basis of the interaction of measles virus with its cellular receptors: implications for vaccine development. Recent Res Dev Virol 1 (1999) 467-484
29. Li L., and Qi Y. A novel amino acid position in hemagglutinin glycoprotein of measles virus is responsible for hemadsorption and CD46 binding. Arch Virol 147 (2002) 775-786
30. Masse N., Barrett T., Muller C.P., Wild T.F., and Buckland R. Identification of a second major site for CD46 binding in the hemagglutinin protein from a laboratory strain of measles virus (MV): potential consequences for wild-type MV infection. J Virol 76 (2002) 13034-13038
31. Tahara M., Takeda M., Seki F., Hashiguchi T., and Yanagi Y. Multiple amino acid substitutions in hemagglutinin are necessary for wild-type measles virus to acquire the ability to use receptor CD46 efficiently. J Virol 81 (2007) 2564-2572
32. Masse N., Ainouze M., Neel B., Wild T.F., Buckland R., and Langedijk J.P. Measles virus (MV) hemagglutinin: evidence that attachment sites for MV receptors SLAM and CD46 overlap on the globular head. J Virol 78 (2004) 9051-9063
33. Vongpunsawad S., Oezgun N., Braun W., and Cattaneo R. Selectively receptor-blind measles viruses: identification of residues necessary for SLAM- or CD46-induced fusion and their localization on a new hemagglutinin structural model. J Virol 78 (2004) 302-313
34. Hashiguchi T., Kajikawa M., Maita N., Takeda M., Kuroki K., Sasaki K., et al. Crystal structure of measles virus hemagglutinin provides insight into effective vaccines. Proc Natl Acad Sci USA 104 (2007) 19535-19540
35. Navaratnarajah C.K., Vongpunsawad S., Oezguen N., Stehle T., Braun W., Hashiguchi T., et al. Dynamic interaction of the measles virus hemagglutinin with its receptor signaling lymphocytic activation molecule (SLAM, CD150). J Biol Chem 283 (2008) 11763-11771
36. + lymphocytes and dendritic cells during measles virus infection of macaques. PLoS Pathogens 3 (2007) e178
37. Kobune F., Sakata H., and Sugiura A. Marmoset lymphoblastoid cells as a sensitive host for isolation of measles virus. J Virol 64 (1990) 700-705
38. Tatsuo H., Okuma K., Tanaka K., Ono N., Minagawa H., Takade A., et al. Virus entry is a major determinant of cell tropism of Edmonston and wild-type strains of measles virus as revealed by vesicular stomatitis virus pseudotypes bearing their envelope proteins. J Virol 74 (2000) 4139-4145
39. Takeda M., Ohno S., Seki F., Hashimoto K., Miyajima N., Takeuchi K., et al. Efficient rescue of measles virus from cloned cDNA using SLAM-expressing Chinese hamster ovary cells. Virus Res 108 (2005) 161-165
40. Ohgimoto K., Ohgimoto S., Ihara T., Mizuta H., Ishido S., Ayata M., et al. Difference in production of infectious wild-type and vaccine viruses in monocyte-derived dendritic cells. Virus Res 123 (2007) 1-8
41. Takeda M., Takeuchi K., Miyajima N., Kobune F., Ami Y., Nagata N., et al. Recovery of pathogenic measles virus from cloned cDNA. J Virol 74 (2000) 6643-6647
42. Nakayama T., Komase K., Uzuka R., Hoshi A., and Okafuji T. Leucine at position 278 of the AIK-C measles virus vaccine strain fusion protein is responsible for reduced syncytium formation. J Gen Virol 82 (2001) 2143-2150
43. Ayata M., Shingai M., Ning X., Matsumoto M., Seya T., Otani S., et al. Effect of the alterations in the fusion protein of measles virus isolated from brains of patients with subacute sclerosing panencephalitis on syncytium formation. Virus Res 130 (2007) 260-268
44. Ohgimoto S., Tabata N., Suga S., Nishio M., Ohta H., Tsurudome M., et al. Molecular characterization of fusion regulatory protein-1 (FRP-1) that induces multinucleated giant cell formation of monocytes and HIV gp160-mediated cell fusion. FRP-1 and 4F2/CD98 are identical molecules. J Immunol 155 (1995) 3585-3592
45. Parks C.L., Lerch R.A., Walpita P., Wang H.P., Sidhu M.S., and Udem S.A. Comparison of predicted amino acid sequences of measles virus strains in the Edmonston vaccine lineage. J Virol 75 (2001) 910-920
46. Hashimoto K., Ono N., Tatsuo H., Minagawa H., Takeda M., Takeuchi K., et al. SLAM (CD150)-independent measles virus entry as revealed by recombinant virus expressing green fluorescent protein. J Virol 76 (2002) 6743-6749
47. Takeuchi K., Takeda M., Miyajima N., Kobune F., Tanabayashi K., and Tashiro M. Recombinant wild-type and Edmonston strain measles viruses bearing heterologous H proteins: role of H protein in cell fusion and host cell specificity. J Virol 76 (2002) 4891-4900
48. Hsu E.C., Doerig R.E., Sarangi F., Marcil A., Iorio C., and Richardson C.D. Artificial mutations and natural variations in the CD46 molecules from human and monkey cells define regions important for measles virus binding. J Virol 71 (1997) 6144-6154
49. Murakami Y., Seya T., Kurita M., Fukui A., Ueda S., and Nagasawa S. Molecular cloning of membrane cofactor protein (MCP; CD46) on B95a cell, an Epstein-Barr virus-transformed marmoset B cell line: B95a-MCP is susceptible to infection by the CAM, but not the Nagahata strain of the measles virus. Bichem J 330 (1998) 1351-1359
50. de Witte L., de Vries R.D., van der Vlist M., Yueksel S., Litjens M., de Swart R.L., et al. DC-SIGN and CD150 have distinct roles in transmission of measles virus from dendritic cells to T-Lymphocytes. PLoS Pathogens 4 (2008) e1000049
51. Ohgimoto S., Ohgimoto K., Niewiesk S., Klagge I.M., Pfeuffer J., Johnston I.C.D., et al. The haemagglutinin protein is an important determinant of measles virus tropism for dendritic cells in vitro. J Gen Virol 82 (2001) 1835-1844
52. Tahara M., Takeda M., and Yanagi Y. Contributions of matrix and large protein genes of the measles virus Edmonston strain to growth in cultured cells as revealed by recombinant viruses. J Virol 79 (2005) 15218-15225
53. de Witte L., Abt M., Schneider-Schaulies S., van Kooyk Y., and Geijtenbeek T.B.H. Measles virus targets DC-SIGN to enhance dendritic cell infection. J Virol 80 (2006) 3477-3486
54. Anderson B.D., Nakamura T., Russell S.J., and Peng K.W. High CD46 receptor density determines preferential killing of tumor cells by oncolytic measles virus. Cancer Res 64 (2004) 4919-4926
55. Hasegawa K., Hu C., Nakamura T., Marks J.D., Russell S.J., and Peng K.W. Affinity thresholds for membrane fusion triggering by viral glycoproteins. J Virol 81 (2007) 13149-13157
56. Escoffier C., and Gerlier D. Infection of chicken embryonic fibroblasts by measles virus: adaptation at the virus entry level. J Virol 73 (1999) 5220-5224
57. Fukuda A., and Sugiura A. Temperature-dependent growth restriction in measles vaccine strains. Jpn J Med Sci Biol 36 (1983) 331-335
58. Komase K., Nakayam T., Iijima M., Miki K., Kawanishi R., and Uejima H. The phosphoprotein of attenuated measles AIK-C vaccine strain contributes to its temperature-sensitive phenotype. Vaccine 24 (2006) 826-834
59. Takeda M., Ohno S., Tahara M., Takeuchi H., Shirogane Y., Ohmura H., et al. Measles Viruses possessing the polymerase protein genes of the Edmonston vaccine strain exhibit attenuated gene expression and growth in cultured cells and SLAM knock-in mice. J Virol 82 (2008) 11979-11984
60. Naniche D., Yeh A., Eto D., Manchester M., Friedman R.M., and Oldstone M.B.A. Evasion of host defenses by measles virus: wild-type measles virus infection interferes with induction of α/β interferon production. J Virol 74 (2000) 7478-7484
61. Shingai M., Ebihara T., Begum N.A., Kato A., Honma T., Matsumoto K., et al. Differential type I IFN-inducing abilities of wild-type versus vaccine strains of measles virus. J Immunol 179 (2008) 6123-6133
62. Ohno S., Ono N., Takeda M., Takeuchi K., and Yanagi Y. Dissection of measles virus V protein in relation to its ability to block alpha/beta interferon signal transduction. J Gen Virol 85 (2004) 2991-2999
63. Condack C., Grivel J.C., Devaux P., Margolis L., and Cattaneo R. Measles virus vaccine attenuation: Suboptimal infection of lymphatic tissue and tropism alteration. J Infect Dis 196 (2007) 541-549