TprK gene regions are not suitable for epidemiological syphilis typing

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 28, Issue 7, 2009, Pages 875-878

  Heymans, R ^a   Kolader, M E ^b   Van Der Helm, J J ^c   Coutinho, R A ^d   Bruisten, S M ^a,b  

^a Amsterdam Health Service   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c National Institute for Public Health and Environment ^*  (Netherlands)

^d NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PROTEIN TPRK; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BACTERIAL TRANSMISSION; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MALE HOMOSEXUAL; MOLECULAR TYPING; MORBIDITY; PRIORITY JOURNAL; SYPHILIS; TREPONEMA PALLIDUM; ULCER;

ADULT; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; CLUSTER ANALYSIS; CONTACT TRACING; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PORINS; SYPHILIS; TREPONEMA PALLIDUM;

EID: 67349197175     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-009-0717-5     Document Type: Article

References (9)

1. IG Stolte NH Dukers JB de Wit 2001 Increase in sexually transmitted infections among homosexual men in Amsterdam in relation to HAART Sex Transm Infect 77 184 186 (Pubitemid 32595739)
2. JL Wylie T Cabral AM Jolly 2005 Identification of networks of sexually transmitted infection: a molecular, geographic, and social network analysis J Infect Dis 191 899 906 (Pubitemid 40349805)
3. ME Kolader NH Dukers AK van der Bij 2006 Molecular epidemiology of Neisseria gonorrhoeae in Amsterdam, The Netherlands, shows distinct heterosexual and homosexual networks J Clin Microbiol 44 2689 2697 (Pubitemid 44228558)
4. A Centurion-Lara C Godornes C Castro 2000 The tprK gene is heterogeneous among Treponema pallidum strains and has multiple alleles Infect Immun 68 824 831 (Pubitemid 30056542)
5. RE LaFond A Centurion-Lara C Godornes 2003 Sequence diversity of Treponema pallidum subsp. pallidum tprK in human syphilis lesions and rabbit-propagated isolates J Bacteriol 185 6262 6268 (Pubitemid 37305525)
6. SM Bruisten I Cairo H Fennema 2001 Diagnosing genital ulcer disease in a clinic for sexually transmitted diseases in Amsterdam, The Netherlands J Clin Microbiol 39 601 605 (Pubitemid 32150825)
7. P French 2007 Syphilis BMJ 334 143 147 (Pubitemid 46173959)
8. RE LaFond A Centurion-Lara C Godornes 2006 TprK sequence diversity accumulates during infection of rabbits with Treponema pallidum subsp. pallidum Nichols strain Infect Immun 74 1896 1906 (Pubitemid 43346827)
9. CA Morgan BJ Molini SA Lukehart 2002 Segregation of B and T cell epitopes of Treponema pallidum repeat protein K to variable and conserved regions during experimental syphilis infection J Immunol 169 952 957 (Pubitemid 34753453)