Determination of bencycloquidium bromide in human urine using weak cation-exchange solid-phase extraction and LC-ESI-MS: Method validation and application to kinetic study of urinary excretion

Journal of Pharmaceutical and Biomedical Analysis

Volumn 50, Issue 1, 2009, Pages 35-40

  Zhou, Wenjia ^a   Ding, Li ^a   Xu, Guili ^b   Wang, Yongqing ^c   Sun, Luning ^a   He, Jianchang ^b   Huang, Yao ^a   Hu, Linlin ^a   Chen, Xiaoping ^d  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b KUNMING GENERAL HOSPITAL   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

^d Beijing Shiqiao Biological and Pharmaceutical Co Ltd   (China)

Author keywords

Bencycloquidium bromide; LC MS; Pharmacokinetics; SPE; Weak cation exchange

Indexed keywords

BENCYCLOQUIDIUM BROMIDE; BROMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; CATION EXCHANGE; CHEMICAL STRUCTURE; HUMAN; KINETICS; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PURIFICATION; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; URINARY EXCRETION; VALIDATION STUDY;

BICYCLO COMPOUNDS, HETEROCYCLIC; CATION EXCHANGE RESINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; KINETICS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 67349192178     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.03.012     Document Type: Article

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