메뉴 건너뛰기




Volumn 8, Issue 6, 2009, Pages 515-519

Critical analysis of rituximab-induced serological changes in connective tissue diseases

Author keywords

Autoantibody; B lymphocyte; BAFF; Connective tissue diseases; Immunoglobulin; Rituximab

Indexed keywords

AUTOANTIBODY; B CELL ACTIVATING FACTOR; CD20 ANTIBODY; COMPLEMENT COMPONENT C1Q ANTIBODY; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; DNA ANTIBODY; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LA ANTIBODY; RHEUMATOID FACTOR; RIBONUCLEOPROTEIN ANTIBODY; RITUXIMAB; RO ANTIBODY; SM ANTIBODY;

EID: 67349186964     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2009.01.007     Document Type: Review
Times cited : (38)

References (40)
  • 1
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • Chan O.T., Hannum L.G., Haberman A.M., Madaio M.P., and Shlomchik M.J. A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med 189 (1999) 1639-1648
    • (1999) J Exp Med , vol.189 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 2
    • 0033033201 scopus 로고    scopus 로고
    • Do self-perpetuating B lymphocytes drive human autoimmune disease?
    • Edwards J.C., Cambridge G., and Abrahams V.M. Do self-perpetuating B lymphocytes drive human autoimmune disease?. Immunology 97 (1999) 188-196
    • (1999) Immunology , vol.97 , pp. 188-196
    • Edwards, J.C.1    Cambridge, G.2    Abrahams, V.M.3
  • 3
    • 0035555161 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity
    • Lipsky P.E. Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity. Nat Immunol 2 (2001) 764-766
    • (2001) Nat Immunol , vol.2 , pp. 764-766
    • Lipsky, P.E.1
  • 4
    • 33845487863 scopus 로고    scopus 로고
    • Is B-cell the conductor of the lymphocyte orchestra in the salivary glands of patients with primary Sjögren's syndrome
    • Youinou P., Daridon C., Saraux A., Devauchelle V., and Pers J. Is B-cell the conductor of the lymphocyte orchestra in the salivary glands of patients with primary Sjögren's syndrome. Clin Exp Rheumatol 24 (2006) 491-492
    • (2006) Clin Exp Rheumatol , vol.24 , pp. 491-492
    • Youinou, P.1    Daridon, C.2    Saraux, A.3    Devauchelle, V.4    Pers, J.5
  • 5
    • 0035093233 scopus 로고    scopus 로고
    • Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes
    • Edwards J.C., and Cambridge G. Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes. Rheumatology (Oxford) 40 (2001) 205-211
    • (2001) Rheumatology (Oxford) , vol.40 , pp. 205-211
    • Edwards, J.C.1    Cambridge, G.2
  • 6
    • 38049065080 scopus 로고    scopus 로고
    • Does the BAFF dysregulation play a major role in the pathogenesis of systemic lupus erythematosus?
    • Binard A., Le Pottier L., Saraux A., Devauchelle-Pensec V., Pers J., and Youinou P. Does the BAFF dysregulation play a major role in the pathogenesis of systemic lupus erythematosus?. J Autoimmun 30 (2008) 63-67
    • (2008) J Autoimmun , vol.30 , pp. 63-67
    • Binard, A.1    Le Pottier, L.2    Saraux, A.3    Devauchelle-Pensec, V.4    Pers, J.5    Youinou, P.6
  • 7
    • 33746961890 scopus 로고    scopus 로고
    • Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
    • Cohen S.B., Emery P., Greenwald M.W., Dougados M., Furie R.A., Genovese M.C., et al. Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum 54 (2006) 2793-2806
    • (2006) Arthritis Rheum , vol.54 , pp. 2793-2806
    • Cohen, S.B.1    Emery, P.2    Greenwald, M.W.3    Dougados, M.4    Furie, R.A.5    Genovese, M.C.6
  • 8
    • 37149035531 scopus 로고    scopus 로고
    • Safety and efficacy of additional courses of rituximab in patients with active rheumatoid arthritis: an open-label extension analysis
    • Keystone E., Fleischmann R., Emery P., Furst D.E., van Vollenhoven R., Bathon J., et al. Safety and efficacy of additional courses of rituximab in patients with active rheumatoid arthritis: an open-label extension analysis. Arthritis Rheum 56 (2007) 3896-3908
    • (2007) Arthritis Rheum , vol.56 , pp. 3896-3908
    • Keystone, E.1    Fleischmann, R.2    Emery, P.3    Furst, D.E.4    van Vollenhoven, R.5    Bathon, J.6
  • 9
    • 33750964016 scopus 로고    scopus 로고
    • B cell depletion therapy in systemic lupus erythematosus: effect on autoantibody and antimicrobial antibody profiles
    • Cambridge G., Leandro M.J., Teodorescu M., Manson J., Rahman A., Isenberg D.A., et al. B cell depletion therapy in systemic lupus erythematosus: effect on autoantibody and antimicrobial antibody profiles. Arthritis Rheum 54 (2006) 3612-3622
    • (2006) Arthritis Rheum , vol.54 , pp. 3612-3622
    • Cambridge, G.1    Leandro, M.J.2    Teodorescu, M.3    Manson, J.4    Rahman, A.5    Isenberg, D.A.6
  • 10
    • 33644914684 scopus 로고    scopus 로고
    • Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse
    • Cambridge G., Stohl W., Leandro M.J., Migone T., Hilbert D.M., and Edwards J.C.W. Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse. Arthritis Rheum 54 (2006) 723-732
    • (2006) Arthritis Rheum , vol.54 , pp. 723-732
    • Cambridge, G.1    Stohl, W.2    Leandro, M.J.3    Migone, T.4    Hilbert, D.M.5    Edwards, J.C.W.6
  • 12
    • 34548559383 scopus 로고    scopus 로고
    • Efficacy of anti-CD20 treatment in patients with rheumatoid arthritis resistant to a combination of methotrexate/anti-TNF therapy
    • Bokarewa M., Lindholm C., Zendjanchi K., Nadali M., and Tarkowski A. Efficacy of anti-CD20 treatment in patients with rheumatoid arthritis resistant to a combination of methotrexate/anti-TNF therapy. Scand J Immunol 66 (2007) 476-483
    • (2007) Scand J Immunol , vol.66 , pp. 476-483
    • Bokarewa, M.1    Lindholm, C.2    Zendjanchi, K.3    Nadali, M.4    Tarkowski, A.5
  • 13
    • 34249795160 scopus 로고    scopus 로고
    • Changes in macrophage function after rituximab treatment in patients with rheumatoid arthritis
    • Toubi E., Kessel A., Slobodin G., Boulman N., Pavlotzky E., Zisman D., et al. Changes in macrophage function after rituximab treatment in patients with rheumatoid arthritis. Ann Rheum Dis 66 (2007) 818-820
    • (2007) Ann Rheum Dis , vol.66 , pp. 818-820
    • Toubi, E.1    Kessel, A.2    Slobodin, G.3    Boulman, N.4    Pavlotzky, E.5    Zisman, D.6
  • 15
    • 52449085305 scopus 로고    scopus 로고
    • Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab
    • Rosengren S., Wei N., Kalunian K.C., Zvaifler N.J., Kavanaugh A., and Boyle D.L. Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab. Arthritis Res Ther 10 (2008) R105
    • (2008) Arthritis Res Ther , vol.10
    • Rosengren, S.1    Wei, N.2    Kalunian, K.C.3    Zvaifler, N.J.4    Kavanaugh, A.5    Boyle, D.L.6
  • 16
    • 38149044612 scopus 로고    scopus 로고
    • Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response
    • Thurlings R.M., Vos K., Wijbrandts C.A., Zwinderman A.H., Gerlag D.M., and Tak P.P. Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response. Ann Rheum Dis 67 (2008) 917-925
    • (2008) Ann Rheum Dis , vol.67 , pp. 917-925
    • Thurlings, R.M.1    Vos, K.2    Wijbrandts, C.A.3    Zwinderman, A.H.4    Gerlag, D.M.5    Tak, P.P.6
  • 17
    • 39549108298 scopus 로고    scopus 로고
    • Treatment of refractory SLE with rituximab plus cyclophosphamide: clinical effects, serological changes, and predictors of response
    • Jónsdóttir T., Gunnarsson I., Risselada A., Henriksson E.W., Klareskog L., and van Vollenhoven R.F. Treatment of refractory SLE with rituximab plus cyclophosphamide: clinical effects, serological changes, and predictors of response. Ann Rheum Dis 67 (2008) 330-334
    • (2008) Ann Rheum Dis , vol.67 , pp. 330-334
    • Jónsdóttir, T.1    Gunnarsson, I.2    Risselada, A.3    Henriksson, E.W.4    Klareskog, L.5    van Vollenhoven, R.F.6
  • 18
    • 28544449032 scopus 로고    scopus 로고
    • B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients
    • Leandro M.J., Cambridge G., Edwards J.C., Ehrenstein M.R., and Isenberg D.A. B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients. Rheumatology (Oxford) 44 (2005) 1542-1545
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 1542-1545
    • Leandro, M.J.1    Cambridge, G.2    Edwards, J.C.3    Ehrenstein, M.R.4    Isenberg, D.A.5
  • 19
    • 4043179907 scopus 로고    scopus 로고
    • B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab
    • Looney R.J., Anolik J.H., Campbell D., Felgar R.E., Young F., Arend L.J., et al. B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab. Arthritis Rheum 50 (2004) 2580-2589
    • (2004) Arthritis Rheum , vol.50 , pp. 2580-2589
    • Looney, R.J.1    Anolik, J.H.2    Campbell, D.3    Felgar, R.E.4    Young, F.5    Arend, L.J.6
  • 22
    • 44349131653 scopus 로고    scopus 로고
    • Longterm clinical and immunological effects of anti-CD20 treatment in patients with refractory systemic lupus erythematosus
    • Lindholm C., Börjesson-Asp K., Zendjanchi K., Sundqvist A., Tarkowski A., and Bokarewa M. Longterm clinical and immunological effects of anti-CD20 treatment in patients with refractory systemic lupus erythematosus. J Rheumatol 35 (2008) 826-833
    • (2008) J Rheumatol , vol.35 , pp. 826-833
    • Lindholm, C.1    Börjesson-Asp, K.2    Zendjanchi, K.3    Sundqvist, A.4    Tarkowski, A.5    Bokarewa, M.6
  • 23
    • 33746565398 scopus 로고    scopus 로고
    • Role of anti-DNA antibodies in the pathogenesis of lupus nephritis
    • Deshmukh U.S., Bagavant H., and Fu S.M. Role of anti-DNA antibodies in the pathogenesis of lupus nephritis. Autoimmun Rev 5 (2006) 414-418
    • (2006) Autoimmun Rev , vol.5 , pp. 414-418
    • Deshmukh, U.S.1    Bagavant, H.2    Fu, S.M.3
  • 24
    • 0027401549 scopus 로고
    • IgA anti-dsDNA antibodies in systemic lupus erythematosus: occurrence, incidence and association with clinical and laboratory variables of disease activity
    • Miltenburg A.M., Roos A., Slegtenhorst L., Daha M.R., and Breedveld F.C. IgA anti-dsDNA antibodies in systemic lupus erythematosus: occurrence, incidence and association with clinical and laboratory variables of disease activity. J Rheumatol 20 (1993) 53-58
    • (1993) J Rheumatol , vol.20 , pp. 53-58
    • Miltenburg, A.M.1    Roos, A.2    Slegtenhorst, L.3    Daha, M.R.4    Breedveld, F.C.5
  • 25
    • 33845869839 scopus 로고    scopus 로고
    • Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE
    • Vallerskog T., Gunnarsson I., Widhe M., Risselada A., Klareskog L., van Vollenhoven R., et al. Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE. Clin Immunol 122 (2007) 62-74
    • (2007) Clin Immunol , vol.122 , pp. 62-74
    • Vallerskog, T.1    Gunnarsson, I.2    Widhe, M.3    Risselada, A.4    Klareskog, L.5    van Vollenhoven, R.6
  • 27
    • 39549100140 scopus 로고    scopus 로고
    • Assessment of rituximab's immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results
    • Kavanaugh A., Rosengren S., Lee S.J., Hammaker D., Firestein G.S., Kalunian K., et al. Assessment of rituximab's immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results. Ann Rheum Dis 67 (2008) 402-408
    • (2008) Ann Rheum Dis , vol.67 , pp. 402-408
    • Kavanaugh, A.1    Rosengren, S.2    Lee, S.J.3    Hammaker, D.4    Firestein, G.S.5    Kalunian, K.6
  • 28
    • 34548513764 scopus 로고    scopus 로고
    • What is the role of rituximab in the treatment of rheumatoid arthritis?
    • Atzeni F., Doria A., Maurizio T., and Sarzi-Puttini P. What is the role of rituximab in the treatment of rheumatoid arthritis?. Autoimmun Rev 6 (2007) 553-558
    • (2007) Autoimmun Rev , vol.6 , pp. 553-558
    • Atzeni, F.1    Doria, A.2    Maurizio, T.3    Sarzi-Puttini, P.4
  • 29
    • 70350517490 scopus 로고    scopus 로고
    • Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis
    • Vallerskog T., Heimbürger M., Gunnarsson I., Zhou W., Wahren-Herlenius M., Trollmo C., et al. Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis. Arthritis Res Ther 8 (2006) R167
    • (2006) Arthritis Res Ther , vol.8
    • Vallerskog, T.1    Heimbürger, M.2    Gunnarsson, I.3    Zhou, W.4    Wahren-Herlenius, M.5    Trollmo, C.6
  • 30
    • 34248597383 scopus 로고    scopus 로고
    • BAFF-modulated repopulation of B lymphocytes in the blood and salivary glands of rituximab-treated patients with Sjögren's syndrome
    • Pers J., Devauchelle V., Daridon C., Bendaoud B., Le Berre R., Bordron A., et al. BAFF-modulated repopulation of B lymphocytes in the blood and salivary glands of rituximab-treated patients with Sjögren's syndrome. Arthritis Rheum 56 (2007) 1464-1477
    • (2007) Arthritis Rheum , vol.56 , pp. 1464-1477
    • Pers, J.1    Devauchelle, V.2    Daridon, C.3    Bendaoud, B.4    Le Berre, R.5    Bordron, A.6
  • 31
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • Mackay F., Woodcock S.A., Lawton P., Ambrose C., Baetscher M., Schneider P., et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 190 (1999) 1697-1710
    • (1999) J Exp Med , vol.190 , pp. 1697-1710
    • Mackay, F.1    Woodcock, S.A.2    Lawton, P.3    Ambrose, C.4    Baetscher, M.5    Schneider, P.6
  • 32
    • 23744476832 scopus 로고    scopus 로고
    • BAFF overexpression is associated with autoantibody production in autoimmune diseases
    • Pers J., Daridon C., Devauchelle V., Jousse S., Saraux A., Jamin C., et al. BAFF overexpression is associated with autoantibody production in autoimmune diseases. Ann N Y Acad Sci 1050 (2005) 34-39
    • (2005) Ann N Y Acad Sci , vol.1050 , pp. 34-39
    • Pers, J.1    Daridon, C.2    Devauchelle, V.3    Jousse, S.4    Saraux, A.5    Jamin, C.6
  • 33
    • 34848912304 scopus 로고    scopus 로고
    • Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy
    • Anolik J.H., Barnard J., Owen T., Zheng B., Kemshetti S., Looney R.J., et al. Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy. Arthritis Rheum 56 (2007) 3044-3056
    • (2007) Arthritis Rheum , vol.56 , pp. 3044-3056
    • Anolik, J.H.1    Barnard, J.2    Owen, T.3    Zheng, B.4    Kemshetti, S.5    Looney, R.J.6
  • 34
    • 34548151122 scopus 로고    scopus 로고
    • B cell depletion therapy in systemic lupus erythematosus: long-term follow-up and predictors of response
    • Ng K.P., Cambridge G., Leandro M.J., Edwards J.C.W., Ehrenstein M., and Isenberg D.A. B cell depletion therapy in systemic lupus erythematosus: long-term follow-up and predictors of response. Ann Rheum Dis 66 (2007) 1259-1262
    • (2007) Ann Rheum Dis , vol.66 , pp. 1259-1262
    • Ng, K.P.1    Cambridge, G.2    Leandro, M.J.3    Edwards, J.C.W.4    Ehrenstein, M.5    Isenberg, D.A.6
  • 36
    • 18944398750 scopus 로고    scopus 로고
    • Short-lived plasmablasts dominate the early spontaneous rheumatoid factor response: differentiation pathways, hypermutating cell types, and affinity maturation outside the germinal center
    • William J., Euler C., and Shlomchik M.J. Short-lived plasmablasts dominate the early spontaneous rheumatoid factor response: differentiation pathways, hypermutating cell types, and affinity maturation outside the germinal center. J Immunol 174 (2005) 6879-6887
    • (2005) J Immunol , vol.174 , pp. 6879-6887
    • William, J.1    Euler, C.2    Shlomchik, M.J.3
  • 38
    • 0036676817 scopus 로고    scopus 로고
    • Efficacy of selective B cell blockade in the treatment of rheumatoid arthritis: evidence for a pathogenetic role of B cells
    • De Vita S., Zaja F., Sacco S., De Candia A., Fanin R., and Ferraccioli G. Efficacy of selective B cell blockade in the treatment of rheumatoid arthritis: evidence for a pathogenetic role of B cells. Arthritis Rheum 46 (2002) 2029-2033
    • (2002) Arthritis Rheum , vol.46 , pp. 2029-2033
    • De Vita, S.1    Zaja, F.2    Sacco, S.3    De Candia, A.4    Fanin, R.5    Ferraccioli, G.6
  • 39
    • 1842554935 scopus 로고    scopus 로고
    • Improvement of refractory rheumatoid arthritis after depletion of B cells
    • Kneitz C., Wilhelm M., and Tony H.P. Improvement of refractory rheumatoid arthritis after depletion of B cells. Scand J Rheumatol 33 (2004) 82-86
    • (2004) Scand J Rheumatol , vol.33 , pp. 82-86
    • Kneitz, C.1    Wilhelm, M.2    Tony, H.P.3
  • 40
    • 33646483031 scopus 로고    scopus 로고
    • The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial
    • Emery P., Fleischmann R., Filipowicz-Sosnowska A., Schechtman J., Szczepanski L., Kavanaugh A., et al. The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Arthritis Rheum 54 (2006) 1390-1400
    • (2006) Arthritis Rheum , vol.54 , pp. 1390-1400
    • Emery, P.1    Fleischmann, R.2    Filipowicz-Sosnowska, A.3    Schechtman, J.4    Szczepanski, L.5    Kavanaugh, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.